欧盟法规
ECHA物质C&L通报上下游产品
Tert-Butyl N-(1-Benzoylpiperidin-4-yl)Carbamate 429677-00-9
N-(1-Benzylpiperidin-4-yl)Formamide 64951-43-5
4-氨基-1-苄基哌啶 4-Amino-1-Benzylpiperidin 50541-93-0
4-叔丁氧羰基氨基哌啶 Tert-Butyl Piperidin-4-Ylcarbamate 73874-95-04-氨基-1-苄基哌啶 以90的收率获得产物1-苄基-4-(Boc-氨基)哌啶
参考文献:Chem. Pharm. Bull. 2001,49(6),788-790
标题:Chem. Pharm. Bull. 2001,49(6),788-790
海关参考信息
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2905122000-异丙醇
2905143000-叔丁醇
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专利信息
专利号:WO-2024132278-A1
优先权日:2022-12-20
标题:Synthesis, pharmacology and use of new water-soluble and selective fms-like tyrosine kinase 3 (flt3) inhibitors
发明人:MAHBOOBI SAVOSH; WIRTH LUKAS; PONGARTZ HERWIG; SELLMER ANDREAS
权利人:UNIV REGENSBURG
摘要:The present application relates to compounds of formula (I) for inhibiting FLT3. The present application further relates to a composition, preferably pharmaceutical composition, comprising a compound or a pharmaceutically acceptable salt thereof and comprising a pharmaceutically acceptable excipient and/or carrier. The present application also relates to a compound or composition for use in medicine. The present application also relates to a compound or composition for use in a method of preventing or treating cancer, preferably blood cancer, more preferably leukemia, even more preferably acute myeloid leukemia (AML). Furthermore, the present application relates to a method of preparing a compound.
专利号:US-6469172-B2
优先权日:2000-03-08
标题:Process for the preparation of chemical compounds
发明人:MALIGRES PETER E; LEE JAEMOON
权利人:MERCK & CO INC
摘要:An improved and efficient synthesis for the preparation of 2-amino-6-[(4-aminopiperidin-1-yl]methyl]pyridine, an intermediate compound in the preparation of muscarinic M3 receptor antagonists, includes as a final step the removal of trimethylacetyl and an amino protecting group from 2-trimethylacetyl-amino-6-[(4-protected aminopiperidin-1-yl)methyl]pyridine.
专利号:EP-4389223-A1
优先权日:2022-12-20
标 题 :Synthesis, pharmacology and use of new water-soluble and selective fms-like tyrosine kinase 3 (flt3) inhibitors
专利号:US-6649627-B1
优先权日:1998-06-18
标 题 :Phenoxylpropanolamines, method for the production thereof and pharmaceutical compositions containing the same
发明人:CECCHI ROBERTO; CROCI TIZIANO; GUZZI UMBERTO; MARSAULT ERIC
权利人:SANOFI SYNTHELABO
摘要:The invention concerns compounds of formula (Ia)whereinR1a represents hydrogen, an -S(O)z -(C1-C4)Alk group, a -CO(C1-C4)Alk group, an -NHSO2-(C1-C4)Alk group, an NCHl (C1-C4) Alk group, a 2-furyl group or a halogen;R2 represents hydrogen or a (C1-C4)Alk group, a (C1-C4) alkoxyl group, a halogen, -COOH, -COO(C1-C4)Alk, -CN, -CONR3R4, -NO2, -SO2NH2, -NHSO2(C1-C4)Alk;m and n are independently 0, 1 or 2;R3 and R4 independently represent hydrogen or a (C1-C4)Alk group;Z is 1 or 2and their salts or solvates, the pharmaceutical compositions that contain them, the process for their preparation, and intermediate synthesis products.