CAS: 7035-03-2; 2-(2-Methoxyphenyl)Acetonitrile

上下游产品

2-(2-methoxyphenyl)acetamide o-Methoxybenzyl bromide potassium cyanide 2-ethoxycarbonyl-2-hydroxy-2-(2-methoxylphenyl)-acetonitrile 1-(6-hydroxy-2,3-dihydro-benzofuran-5-yl)-2-(2-methoxy-phenyl)-ethanone 2-(2-methoxyphenyl)-1-(2,4,6-trihydroxyphenyl)ethanone 6-(2-methoxy-phenyl)-pteridine-2,4,7-triamine ethyl (2-methoxyphenyl)acetate

(2-甲氧基苯基)乙醛置于氨,碘体系中,化学反应 1.0H,以73%的收率获得产物邻甲氧基苯乙腈
参考文献:在无金属氰化物条件下通过 Wittig 反应从醛中一锅法制备 C1-同系化脂肪腈
标题:在无金属氰化物条件下通过 Wittig 反应从醛中一锅法制备 C1-同系化脂肪腈
摘要:通过用(甲氧基甲基)三苯基鏻叶立德处理芳香族和脂肪族醛,然后用 Ptsoh(ts = 对甲苯磺酰基)水解所得甲基乙烯基醚并用分子碘处理,实现了获得 C1 同系脂肪腈的一锅法和氨水在无金属氰化物条件下.使用本方法成功地获得了新戊基型腈,这些方法不能通过将新戊醇转化为甲苯磺酸盐并用金属氰化物处理的常规方法获得.
DOI:10.1002/ejoc.201700277

专利信息

专利号:US-7238823-B2
优先权日:2005-06-30
标 题 :Platinum complexes with mononitrile-containing ligands
发明人：XIAO ZEJUN; HAUSHEER FREDERICK H; PETLURU PAVANKUMAR
权利人:BIONUMERIK PHARMACEUTICALS INC
摘要:Disclosed herein are novel platinum-based complexes possessing one nitrile substituent group (mononitrile) covalently-bonded to the platinum, one or more nitrogen donor ligands capable of forming hydrogen bonds with the bases in DNA or RNA and leaving groups (i.e., L 1 and L 2 ) which can be hydrolyzed in vivo to active species, which can then form coordinate adducts with DNA or RNA at the Guanine or Adenine bases thereof. Also disclosed herein are the reaction schemes for the synthesis of said platinum complexes, as well as methods of treatment of various types of cancer by the administration of a pharmaceutically-effective dose of said novel platinum complexes.

专利号:US-7569606-B2
优先权日:2006-01-26
标 题 :Platinum complexes with mononitrile-containing ligands
发明人：XIAO ZEJUN; HAUSHEER FREDERICK H; PETLURU PAVANKUMAR
权利人:BIONUMERIK PHARMACEUTICALS INC
摘要:Disclosed herein are novel platinum-based complexes possessing one nitrile substituent group (mononitrile) covalently-bonded to the platinum, one or more nitrogen donor ligands capable of forming hydrogen bonds with the bases in DNA or RNA and leaving groups (i.e., L 1 and L 2 )which can be hydrolyzed iii vivo to active species, which can then form coordinate adducts with DNA or RNA at the Guanine or Adenine bases thereof. Also disclosed herein are the reaction schemes for the synthesis of said platinum complexes, as well as methods of treatment of various types of cancer by the administration of a pharmaceutically-effective dose of said novel platinum complexes.

专利号:US-2011296543-A1
优先权日:2006-06-01
标题:Nucleic acids and proteins and methods for making and using them
发明人：CHANG HWAI; MATHUR ERIC J; CAYOUETTE MICHELLE; ROBERTSON DAN E; HUGENHOLTZ PHILIP; WARNECKE FALK; LEADBETTER JARED R; IVANOVA NATALIA; LUGINBUHL PETER; HUTCHISON DON
权利人:CHANG HWAI; MATHUR ERIC J; CAYOUETTE MICHELLE; ROBERTSON DAN E; HUGENHOLTZ PHILIP; WARNECKE FALK; LEADBETTER JARED R; IVANOVA NATALIA; LUGINBUHL PETER; HUTCHISON DON; UNIV CALIFORNIA; CALIFORNIA INST OF TECHN; VERENIUM CORP
摘要:The invention provides polypeptides, including enzymes, structural proteins and binding proteins, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. Polypeptides, including enzymes and antibodies, and nucleic acids of the invention can be used in industrial, experimental, food and feed processing, nutritional and pharmaceutical applications, e.g., for food and feed supplements, colorants, neutraceuticals, cosmetic and pharmaceutical needs. Polypeptides of the invention can be used in food processing, brewing, bath additives, alcohol production, peptide synthesis, enantioselectivity, hide preparation in the leather industry, waste management and animal degradation, silver recovery in the photographic industry, medical treatment, silk degumming, biofilm degradation, biomass conversion to a biofuel (e.g., a bioethanol, biomethanol, biopropanol or biobutanol, a biodiesel, etc.), biodefense, antimicrobial agents and disinfectants, personal care and cosmetics, biotech reagents, in corn wet milling and pharmaceuticals such as digestive aids and anti-inflammatory (anti-phlogistic) agents.

专利号:CN-117700332-A
优先权日:2023-12-12
标 题:Synthesis method of venlafaxine hydrochloride

专利号:EP-1888511-A1
优先权日:2005-05-05
标 题 :A methacrylate-bound photoisomerizable chromophore, methods for its synthesis and of its intermediates

专利号:WO-2006117791-A1
优先权日:2005-05-05
标题 :A methacrylate-bound photoisomerizable chromophore, methods for its synthesis and of its intermediates