相似化合物
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CAS号75-11-6 二碘甲烷 | CAS号6117-91-5 巴豆醇 | CAS号29555-02-0 2-甲基环丙羧酸 | CAS号74-95-3 二溴甲烷 | CAS号2929-33-1 ethyl (E)-3-(fl... | CAS号71441-77-5 2-甲基环丙烷羧酸甲酯 | CAS号20913-25-1 2-甲基环丙烷-1-羧酸乙酯 | CAS号6142-59-2 2-methylcyclopr... | CAS号594-02-5 1,1-Diiodoethane | CAS号107-18-6 烯丙醇 | CAS号29555-02-0 2-甲基环丙羧酸 | CAS号31950-56-8 4-Bromo-1-pentene2-甲基环丙羧酸置于lithium Aluminium Tetrahydride体系中,用 乙醚 作为反应溶剂,化学反应生成 2-甲基环丙甲醇
参考文献:小环化合物.三十五.甲基取代的环丁基-,环丙基羰基-和烯丙基羰基胺的亚硝酸脱氨基重排的研究1A,B
标题:小环化合物.三十五.甲基取代的环丁基-,环丙基羰基-和烯丙基羰基胺的亚硝酸脱氨基重排的研究1A,B
摘要:已确定在环丙基甲基甲胺,(2-甲基环丙基)-甲胺,2-甲基环丁胺,3-甲基环丁胺,巴豆基甲胺和烯丙基甲基甲胺的亚硝酸脱氨基中形成的醇混合物的组成.这些结果和相应醇在强酸性介质中异构化条件下的行为可以通过假设形成三种不等价的,不对称的,非经典的阳离子中间体来解释,类似于先前为其他小环衍生物的碳正离子反应提出的那些. .
DOI:10.1021/ja01478A028
专利信息
专利号:US-2004053999-A1
优先权日:1997-09-17
标题 :Novel compounds and methods for synthesis and therapy
发明人:BISCHOFBERGER NORBERT W; DAHL TERRENCE C; HITCHCOCK MICHAEL J M; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; MILLS ROGER G; WILLIAMS MATTHEW A
摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.
专利号:US-6225341-B1
优先权日:1995-02-27
标 题:Compounds and methods for synthesis and therapy
发明人:BISCHOFBERGER NORBERT W; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; WILLIAMS MATTHEW A
权利人:GILEAD SCIENCES INC
摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.
专利号:US-7825149-B2
优先权日:2006-01-19
标 题 :Substituted imidazoles
发明人:CHUBB NATHAN ANTHONY LOGAN; COX MARK ROGER; DAUVERGNE JEROME SEBASTIEN; EWIN RICHARD ANDREW; LAURET CHRISTELLE
权利人:PFIZER LTD
摘要:This invention relates to a range of alpha substituted 2-benzyl substituted imidazole compounds and pharmaceutically acceptable salts and solvates thereof, to compositions comprising such compounds, processes for their synthesis and their use as parasiticides.