CAS: 5949-05-3; (S)-3,7-Dimethyloct-6-Enal

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CAS号106-26-3 (Z)-citral | CAS号7540-51-4 (-)-beta-香茅醇 | CAS号5392-40-5 柠檬醛 | CAS号141-27-5 (E)-3,7-二甲基-2,6-辛二烯醛 | CAS号106-24-1 香叶醇; (E)-3,7-二甲... | CAS号106-25-2 橙花醇 | CAS号67392-54-5 N,N-diethyl-N-{... | CAS号40267-53-6 (2E)-N,N-diethy... | CAS号106-23-0 香茅醛 | CAS号617-53-8 2-Butenedioic a... | CAS号141608-97-1 (3S)-3,7-dimeth... | CAS号2111-53-7 (S)-(-)-香茅酸 | CAS号7540-51-4 (-)-beta-香茅醇 | CAS号3564-95-2 (1S,3S,4S)-p-me... | CAS号122517-60-6 Isopulegol | CAS号104870-56-6 (+)-异胡薄荷醇 | CAS号312619-58-2 (4S)-6-Bromo-4-... | CAS号109215-55-6 4,7-dimethyl-1,...

📜柠檬醛置于glucose Dehydrogenase,葡萄糖,Ene Reductase From Gluconobacter Oxydans,还原型辅酶ii(Nadph)四钠盐体系中,化学反应 1.0H,以99%的收率获得产物
参考文献:对映选择性重排与加水结合:由α,β-不饱和醛直接合成对映体纯的饱和羧酸
标题:对映选择性重排与加水结合:由α,β-不饱和醛直接合成对映体纯的饱和羧酸
摘要:描述了一种新型的有机合成方法,该方法可将α,β-不饱和醛直接单锅转化为饱和羧酸.作为唯一的试剂,需要将水完全整合到产品中.该串联过程在理想的原子经济下进行,由两个耦合的氧化还原生物转化组成,而无需外部辅助底物进行辅因子再生.nadph依赖的烯还原酶催化α,β-不饱和醛的cc双键的初始还原,导致形成饱和醛和nadp +.然后将醛中间体氧化为相应的羧酸,从而为下一个催化循环再生nadph.当使用前手性α,β-不饱和醛作为底物时,相应的羧酸可对映体选择性地形成,其对映体选择性的分离度最高可达> 99%ee,如证明的那样,可用于将柠檬酸转化为(S)-香茅酸.
DOI:10.1002/cctc.201300764

专利信息

专利号:US-6423877-B1
优先权日:1999-11-15
标题:Synthesis of pseudopterosin compounds
发明人：COREY ELIAS J
权利人:HARVARD COLLEGE
摘要:The present invention is directed to a new synthetic route to pseudopterosin aglycone (3): n a key intermediate for the synthesis of a group of antiinflammatory natural products including pseudopterosin A (1) and E (2). The pathway of synthesis starts with the abundant and inexpensive (S)-(−)-limonene and its long-known cyclic hydroboration product (4) and leads to the chiral hydroxy ketone (6). Conversion of (6) to (10) followed by a novel aromatic annulation produced (15) which underwent highly diastereoselective cyclization to afford the protected pseudopterosin aglycone (16). The naturally occurring pseudopterosins such as (1) and (2) are readily available from this key intermediate.

专利号:WO-0053313-A2
优先权日:1999-03-09
标 题:Lanthanide catalysts for synthesis of compounds and combinatorial libraries

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优先权日:2020-12-31
标 题 :Process for the asymmetric synthesis of isopiperitenol

专利号:WO-2022144436-A1
优先权日:2020-12-31
标 题 :Process for the asymmetric synthesis of isopiperitenol

专利号:CN-115739187-A
优先权日:2022-10-13
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专利号:CN-113717910-B
优先权日:2021-07-20
标 题:A three-enzyme co-expression recombinant bacteria and its application in the synthesis of (S)-citronellol