专利号:US-7078406-B2 优先权日:2001-10-09 标 题 :Substituted diphenyloxazoles, the synthesis thereof, and the use thereof as fluorescence probes 发明人:CARVER JR THEODORE E; RINKER JAMES M 权利人:JOHNSON & JOHNSON PHARM RES 摘要:The present invention is directed to a compound of Formula I: n nwherein A, R 1 , and R 2 are defined herein. The present invention is also directed to compositions comprising compounds of Formula I, methods of using compounds of Formula I, and methods of making compounds of Formula I.
专利号:US-5512577-A 优先权日:1994-06-02 标 题:Bicyclic hexahydroaporphine and 1-benzyloctahydroisoquinoline therapeutic compositions and processes for utilizing said compositions 发明人:ROCHE VICTORIA F; OHIA S EDET; ROCHE EDWARD B 权利人:UNIV CREIGHTON 摘要:The invention relates to the method of synthesis of bicyclic hexahydroaporphine compounds which may provide improved therapy for diseases characterized by an increase in intraocular pressure. More specifically, the present invention relates to the preparation of agents which may provide for improved treatment of patients with glaucoma or ocular hypertension. The present invention describes the intraocular pressure lowering capabilities of several of the bicyclic hexahydroaporphine structures.
专利号:MX-PA04003451-A 优先权日:2001-10-09 标 题:SUBSTITUTED DIFENYLOXAZOLS, THE SYNTHESIS OF THE SAME AND THE USE OF THE SAME AS FLUORESCENCE DETECTORS.
专利号:US-2007148246-A1 优先权日:2005-08-11 标题:Nucleic Acid-Based Matrixes 发明人:LUO DAN; LI YOUGEN 权利人:LUO DAN; LI YOUGEN 摘要:Various nucleic acid-based matrixes are provided, comprising nucleic acid monomers as building blocks, as well as nucleic acids encoding proteins, so as to produce novel biomaterials. Methods of utilizing such biomaterials include delivery of biologically active agents, cell and tissue culture, and cell-free protein synthesis.
专利号:US-2014315720-A1 优先权日:2012-10-24 标 题 :Polysaccharide ester microspheres and methods and articles relating thereto 发明人:FALLON DENIS G; GARRETT THOMAS S; KIZER LAWTON E; ZAZZARA KAREN L; COMBS MICHAEL T; JOHNSON RICHARD K; DEHART GARY 权利人:CELANESE ACETATE LLC 摘要:A method for producing a polysaccharide ester microsphere may include forming a polysaccharide ester product from a polysaccharide synthesis, wherein the polysaccharide ester product comprises a polysaccharide ester and a solvent; diluting the polysaccharide ester product, thereby yielding a polysaccharide ester dope; and forming a plurality of polysaccharide ester microspheres from the polysaccharide ester dope. Suitable polysaccharides may include, but are not limited to, starch, cellulose, hemicellulose, algenates, chitosan, and any combination thereof. Esters thereof may be organic esters (e.g., acetate and the like), inorganic esters (e.g., sulfonates and the like), or combinations thereof. Further, the solids conent of the polysaccharide ester dope, in some instances, may be greater than about 16 wt %.
专利号:US-8486621-B2 优先权日:2005-08-11 标题 :Nucleic acid-based matrixes 发明人:LUO DAN; UM SOONG HO 权利人:LUO DAN; UM SOONG HO; CORNELL RES FOUNDATION INC 摘要:Various nucleic acid-based matrixes are provided, comprising nucleic acid monomers as building blocks, as well as nucleic acids encoding proteins, so as to produce novel biomaterials. Methods of utilizing such biomaterials include cell-free protein synthesis.
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