CAS: 506-48-9; Octacosanoic Acid

该化合物是一种长链饱和脂肪酸,含有分子式C28H56O2,其特征为直链结构,由28个碳原子组成,一端有一个碳原子和碳酸功能组.该化合物一般是白色的,在室内温度下是蜡状的固体,由于长期的疏水碳链,在水中无法溶解,但在乙醇和氯仿等有机溶剂中是溶解的.八氧酸自然存在于各种植物油和动物脂肪中,特别是在某些植物的种子中.它用于生产表面活性剂,乳化剂和各种工业应用中的润滑剂.此外,由于它具有发酵性,它有可能在化妆工业中应用.它的高熔点和稳定性使它适合用于高温应用.

结构式图片

相似化合物

1002-84-2 112-37-8 112-85-6

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

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CAS号557-61-9 1-二十八烷醇 | CAS号1611-56-9 11-溴十一醇 | CAS号55682-92-3 甲基二十八酸酯

合成工艺路线路线简述

    📜二十八烷醇 反应生成 二十八酸
    参考文献:Synthesis Of Long-Chain Fatty Acid Derivatives As A Novel Anti-Alzheimer's Agent
    标题:Synthesis Of Long-Chain Fatty Acid Derivatives As A Novel Anti-Alzheimer's Agent
    摘要:In Order To Develop New Drugs For Alzheimer'S Disease,We Prepared 17 Fatty Acid Derivatives With Different Chain Lengths And Different Numbers And Positions Of Double Bonds By Using Wittig Reaction And Stereospecific Hydrogenation Of Triple Bonds As Key Reactions. Among Them,(4Z,15Z)-octadecadienoic Acid (10) And (23Z,34Z)-Heptatriacontadienoic Acid (16) Showed The Most Potent Neurite Outgrowth Activities On A Beta(25-35)-Treated Rat Cortical Neurons,Which Activities Were Comparable To That Of A Positive Control,Ngf. Both Fatty Acids 10 And 16 Possess Two (Z)-Double Bonds At The N-3 And N-14 Positions,Which Might Be Important For The Neurite Outgrowth Activity. (C) 2013 Elsevier Ltd. All Rights Reserved.
    DOI:10.1016/j.Bmcl.2013.12.008

    海关参考信息

    专利信息


    专利号:US-9643915-B2
    优先权日:2013-03-15
    标题:Methods for the synthesis of sphingomyelins and dihydrosphingomyelins
    发明人:ONICIU DANIELA CARMEN; HECKHOFF STEFAN; OSWALD BENOIT; REBMANN PETER; PEER ANDREAS; GONZALEZ MIGUEL; SAUTER PATRIK
    权利人:CERENIS THERAPEUTICS HOLDING SA
    摘要:The present invention includes methods for the synthesis of sphingomyelins and dihydrosphingomyelins. The present invention also includes methods for the synthesis of sphingosines and dihydrosphingosines. The present invention further includes methods for the synthesis of ceramides and dihydroceramides.

    专利号:US-9708354-B2
    优先权日:2013-03-15
    标 题:Methods for the synthesis of sphingomyelins and dihydrosphingomyelins
    发明人:ONICIU DANIELA CARMEN; HECKHOFF STEFAN; OSWALD BENOIT; REBMANN PETER; PEER ANDREAS; GONZALEZ MIGUEL; SAUTER PATRIK
    权利人:CERENIS THERAPEUTICS HOLDING SA
    摘要:The present invention includes methods for the synthesis of sphingomyelins and dihydrosphingomyelins. The present invention also includes methods for the synthesis of sphingosines and dihydrosphingosines. The present invention further includes methods for the synthesis of ceramides and dihydroceramides.

    专利号:US-12018313-B2
    优先权日:2016-12-28
    标题:Methods, apparatuses, and systems for microorganism strain analysis of complex heterogeneous communities with tracer analytics, determination of functional relationships and interactions thereof, and synthesis of microbial ensembles
    发明人:EMBREE MALLORY
    权利人:NATIVE MICROBIALS INC
    摘要:Methods, apparatuses, and systems for microorganism strain analysis of complex heterogeneous communities with tracer analytics, determination of functional relationships and interactions thereof, and synthesis of microbial ensembles, including dosed microbial ensembles and inoculative microbial ensembles, are disclosed.

    专利号:US-10604479-B2
    优先权日:2013-11-18
    标 题:Continuous process for the one-pot synthesis of metal salts and metal complexes
    发明人:LEONARDI GIULIANO; GASPERONI GIOVANNI
    权利人:VOLARE & CONNECTING LLC; LEONARDI GIULIANO; NOVUS INT INC
    摘要:A continuous process is described for the one-pot synthesis of compounds, such as metal salts and metal complexes, as well as optionally for the protection of the compounds thus obtained by coating and/or impregnation with suitable compounds.

    专利号:US-11583842-B2
    优先权日:2019-07-24
    标题 :Zwitterionic catalysts for (trans)esterification: application in fluoroindole-derivatives and biodiesel synthesis
    发明人:YEUNG YING-YEUNG; LAM YING-PONG; KE ZHIHAI; WANG XINYAN; TAN FEI; NG WING-HIN; TSE YING-LUNG STEVE
    权利人:UNIV HONG KONG CHINESE
    摘要:An amide/iminium zwitterion catalyst has a catalyst pocket size that promotes transesterification and dehydrative esterification. The amide/iminium zwitterions are easily prepared by reacting aziridines with aminopyridines. The reaction can be applied a wide variety of esterification processes including the large-scale synthesis of biodiesel. The amide/iminium zwitterions allow the avoidance of strongly basic or acidic condition and avoidance of metal contamination in the products. Reactions are carried out at ambient or only modestly elevated temperatures. The amide/iminium zwitterion catalyst is easily recycled and reactions proceed in high to quantitative yields.

    专利号:US-11981938-B2
    优先权日:2017-10-05
    标 题 :Microorganisms and methods for the fermentation of cannabinoids
    发明人:SZAMECZ BELA KRISZTIAN; VARSZEGI SZILVIA; NEMETH ATTILA; SZABO LORAND; KUMAR ABHINAV
    权利人:ELESZTO GENETIKA INC
    摘要:Disclosed herein are microorganism and methods that can be used for the synthesis of cannabigerolic acid (CBGA) and cannabinoids. The methods disclosed can be used to produce CBGA, Δ9-tetrahydrocannabinolic acid (THCA), cannabidiolic acid (CBDA), cannabichromenic acid (CBCA), Δ9-tetrahydrocannabinol (THC), cannabidiol (CBD), cannabichromene (CBC). Enzymes useful for the synthesis of CBGA and cannabinoids, include but are not limited to acyl activating enzyme (AAE1), polyketide synthase (PKS), olivetolic acid cyclase (OAC), prenyltransferase (PT), THCA synthase (THCAS), CBDA synthase (CBDAS), CBCA synthase (CBCAS), HMG-Co reductase (HMG1), and/or farnesyl pyrophosphate synthetase (ERG20). The microorganisms can also have one or more genes disrupted, such as gene that that controls beta oxidation of long chain fatty acids.

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Anggarani M, Lin YY, Fang SA, Wu HP, Wu CC, Jane WN, Roscoe TJ, Domergue F, Hsing YC. Morphology and chemical composition of Taiwan oil millet (Eccoilopus formosanus) epicuticular wax. Planta. 2024 Mar 11;259(4):89. doi: 10.1007/s00425-024-04352-y. 35(24):6025-6029. doi: 10.1080/14786419.2020.1815737. Epub 2020 Sep 16.
    13:7199-7211. doi: 10.2147/OTT.S245663.
    4: Ahmed SA, Rahman AA, Elsayed KNM, Abd El-Mageed HR, Mohamed HS, Ahmed SA. Cytotoxic activity, molecular docking, pharmacokinetic properties and quantum mechanics calculations of the brown macroalga Cystoseira trinodis compounds. J Biomol Struct Dyn. 2021 Jul;39(11):3855-3873. doi: 10.1080/07391102.2020.1774418. Epub 2020 Jun 11.

    合成参考文献


    参考文献:10.1002/tcm.10001
    摘要:Gámez R, Rodeiro I, Fernández I, Acosta PC. Preliminary evaluation of the cytotoxic and genotoxic potential of D-003: Mixture of very long chain fatty acids. Teratog Carcinog Mutagen. 2002;22(3):175–81. doi: 10.1002/tcm.10001.
    参考文献:10.1177/1934578x0900401126
    摘要:Radulović N, Blagojević P, Palić R. Composition of Diethyl Ether Flower Extracts of Lonicera fragrantissima Lindl. & Paxton (Caprifoliaceae). Natural Product Communications. 2009 Nov;4(11). doi: 10.1177/1934578x0900401126.
    参考文献:10.1093/jxb/erq002
    摘要:Ebert B, Zöller D, Erban A, Fehrle I, Hartmann J, Niehl A, Kopka J, Fisahn J. Metabolic profiling of Arabidopsis thaliana epidermal cells. J Exp Bot. 2010 Mar;61(5):1321–35.
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