CAS: 50458-77-0; Isoquinoline-3-Carboxamide

相似化合物

26947-41-1 132833-03-5 1628557-04-9

上下游产品

CAS号663170-97-6 5-(2-(diethoxym... | CAS号6624-49-3 异喹啉-3-甲酸 | CAS号27104-73-0 异喹啉-3-羧酸甲酯 | CAS号103890-70-6 2-(二乙氧基甲基)苯甲醛 | CAS号35822-58-3 2-溴苯甲醛二乙缩醛 | CAS号50458-79-2 3-异喹啉甲酸乙酯 | CAS号67123-97-1 1,2,3,4-四氢异喹啉-3-羧酸 | CAS号57060-86-3 1,2,3,4-四氢异喹啉-3-羧酸甲酯 | CAS号26947-41-1 3-氰基异喹啉 | CAS号25475-67-6 3-氨基异喹啉

📜1,2,3,4-四氢异喹啉-3-羧酸甲酯置于palladium On Activated Charcoal,氨体系中,用 Xylene 作为反应溶剂,化学反应生成 3-异喹啉羧酰胺
参考文献:Langry,Kevin C.,Organic Preparations And Procedures International,1994,Vol. 26,# 4,P. 429-438
标题:Langry,Kevin C.,Organic Preparations And Procedures International,1994,Vol. 26,# 4,P. 429-438

专利信息

专利号:US-7501407-B2
优先权日:2001-12-20
标题 :Pyrimidine A2B selective antagonist compounds, their synthesis and use
发明人：CASTELHANO ARLINDO; MCKIBBEN BRYAN; STEINIG ARNO; COLLINGTON ERIC
权利人:OSI PHARM INC
摘要:The subject invention provides compounds having the structure: n nwherein R 1 is substituted or unsubstituted phenyl or a 5-6 membered heterocyclic or heteroaromatic ring containing from 1 to 5 heteroatoms; R 2 is hydrogen, or a substituted or unsubstituted alkyl, —C(O)-alkyl, —C(O)—O-alkyl, alkoxy, cycloalkyl, alkenyl, monocyclic or bicyclic aryl, heteroaryl or heterocyclic moiety; R 3 is hydrogen, or a substituted or unsubstituted alkyl, —C(O)-alkyl, —C(O)—O-alkyl, alkoxy, cycloalkyl, alkenyl, monocyclic or bicyclic aryl, heteroaryl or heterocyclic moiety, or R 2 and R 3 are joined to form a heterocyclic ring; wherein the dashed line represents a second bond which may be present or absent, and when present R 3 is oxygen; R 4 and R 5 are each independently substituted or unsubstituted alkyl, —C(O)-alkyl, —C(O)—O-alkyl, alkoxy, cycloalkyl, alkenyl, monocyclic or bicyclic aryl, heteroaryl or heterocyclic moiety, or R 4 NR 5 together form a substituted or unsubstituted monocyclic or bicyclic, heterocyclic or heteroaryl moiety containing from 1 to 6 heteroatoms;n R 12 is hydrogen, alkyl, halogen or cyano; and n is 0, 1, 2, 3 or 4, or an enantiomer, or a specific tautomer, or a pharmaceutically acceptable salt thereof and a method for treating a disease associated with the A 2b adenosine receptor by administering a therapeutically effective amount of the compounds of the invention.

专利号:CN-111116461-A
优先权日:2019-12-26
标 题:Palladium-catalyzed o-toluidine amide gamma-C- (sp)3) Synthesis method of H sulfur/selenium ether compound

专利号:CN-111116461-B
优先权日:2019-12-26
标题 :Palladium-catalyzed o-toluidine amide gamma-C- (sp)3) Synthesis method of H sulfur/selenium ether compound

专利号:MX-PA04005862-A
优先权日:2001-12-20
标 题 :SELECTED ANTAGONIST COMPOUNDS OF PYRIMIDINE A2B, ITS SYNTHESIS AND USE.