专利号:WO-9925385-A1 优先权日:1997-11-17 标 题:A method of increasing nucleic acid synthesis with ultrasound 发明人:UNGER EVAN C; MCCREERY THOMAS; SADEWASSER DAVID 权利人:IMARX PHARMACEUTICAL CORP 摘要:The present invention is directed to a method of increasing nucleic acid synthesis in a cell comprising administering to the cell a therapeutically effective amount of ultrasound for a therapeutically effective time such that said administration of said ultrasound results in said increased nucleic acid synthesis. The nucleic acid sequence may comprise an endogenous sequence or an exogenous sequence.
专利号:US-2020016134-A1 优先权日:2016-02-16 标 题:Compositions and methods for treating substance abuse disorders 发明人:DETKE MICHAEL; GLOFF CAROL; STRAUB JULIE 权利人:EMBERA NEUROTHERAPEUTICS INC 摘要:The present invention is directed to compositions and methods for treating substance abuse disorders and addiction. In particular, this invention is directed to combinations of low doses of a cortisol synthesis inhibitor, such as metyrapone, in combination with low doses of a benzodiazepine, such as oxazepam. The compositions and methods of the present invention include pharmaceutical compositions and methods that are safe and efficacious for treating animals and humans.
摘要:Drugs in Japan, 6(401), 1982 摘要:Journal of the American Pharmaceutical Association, Scientific Edition., 44(152), 1955 摘要:Schafer, E.W. 1972. The acute oral toxicity of 369 pesticidal, pharmaceutical and other chemicals to wild birds. Toxicology and Applied Pharmacology. 21:315-330. 摘要:Schafer, E. W., Jr., W. A. Bowles Jr., and J. Hurlbut. 1983. The acute oral toxicity and repellency and hazard potential of 998 chemicals to one or more species of wild and domestic birds. Archives of Environmental Contamination and Toxicology 12:355-382. 摘要:Schafer, E.W. Jr. and D.J. Cummings. 1972. An evaluation of 148 compounds as avian immobilizing agents. U.S. Fish and Wildlife Service, Special Scientific Report-Wildlife No.150. 30pp. https://www.aphis.usda.gov/ws/nwrc/chem-effects-db/E_SchaferCunningham72.pdf