CAS: 27810-64-6; Isoquinoline-5-Carboxylic Acid

相似化合物

80278-67-7 27655-41-0 76518-57-5

上下游产品

CAS号27655-41-0 5-氰基异喹啉 | CAS号63927-20-8 (3-bromo-benzyl... | CAS号3132-99-8 间溴苯甲醛 | CAS号569-51-7 1,2,3-苯三甲酸 | CAS号16675-59-5 5-异喹啉甲酸甲酯

📜5-氰基异喹啉置于盐酸,水体系中,化学反应 6.0H,以84%的收率获得异喹啉-5-甲酸
参考文献:Isoquinoline-5-Carboxamide Derivative Having Inhibitory Activity For Protein Kinase
标题:Isoquinoline-5-Carboxamide Derivative Having Inhibitory Activity For Protein Kinase
摘要:从包括式(I)的异喹啉-5-羧酰胺衍生物,药用盐,异构体,水合物和溶剂化物的化合物中选择的化合物对于预防或治疗由蛋白激酶异常激活引起的与异常细胞生长相关的疾病是有效的.

专利信息

专利号:US-5846993-A
优先权日:1992-12-22
标题:HIV protease inhibitors
发明人：DRESSMAN BRUCE A; FRITZ JAMES E; KALDOR STEPHEN W; KALISH VINCENT J; REICH SIEGFRIED HEINZ; TATLOCK JOHN H; RODRIGUEZ MICHAEL J
权利人:AGOURON PHARMA
摘要:HIV protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds, as well as pharmaceutical compositions that contain these compounds and optionally other anti-viral agents as active ingredients, are suitable for treating patients or hosts infected with the HIV virus, which is known to cause AIDS.

专利号:US-6271235-B1
优先权日:1992-12-22
标题:HIV protease inhibitors
发明人：DRESSMAN BRUCE A; FRITZ JAMES E; KALDOR STEPHEN W; KALISH VINCENT J; REICH SIEGFRIED HEINZ; RODRIGUEZ MICHAEL J; SHEPHERD TIMOTHY A; TATLOCK JOHN H; JUNGHEIM LOUIS NICKOLAUS
权利人:AGOURON PHARMA
摘要:HIV protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds, as well as pharmaceutical compositions that contain these compounds and optionally other anti-viral agents as active ingredients, are suitable for treating patients or hosts infected with the HIV virus, which is known to cause AIDS.