CAS: 23470-00-0; 2-Palmitoylglycerol

该化合物是一种甘蓝醇,其特点是含有一种棕榈酸(C16:0)链,在甘油主干骨的第二碳中被浸泡.该化合物是一种单酰甘油醇,因其在各种生物过程中的作用而引人注目,包括作为合成其他脂类的前体和作为信号分子的作用.它通常是在室内温度下一种白色到白色的固体,在乙醇和氯仿等有机溶剂中可溶解,但水溶性有限. 2-帕利基甘油对营养,新陈代谢和细胞研究很感兴趣,因为其可能对细胞功能产生影响,并参与脂类代谢.此外,它可能在食品和化妆品工业中作为乳化剂或稳定剂的应用.与许多脂质一样,其特性可能受到温度和其他物质存在等因素的影响.

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10567-21-2 60562-16-5 17598-94-6

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CAS号56599-87-2 (2-phenyl-1,3-d... | CAS号101036-66-2 2-(palmitoyloxy... | CAS号57-10-3 棕榈酸 | CAS号56-81-5 甘油 | CAS号555-44-2 (三)棕榈酸甘油酯 | CAS号112-39-0 棕榈酸甲酯 | CAS号150-46-9 硼酸三乙酯 | CAS号13460-50-9 偏硼酸 | CAS号10588-87-1 Hexadecanoic ac... | CAS号142-91-6 棕榈酸异丙酯 | CAS号3331-34-8 1-油酰基-2-棕榈酰基-rac-甘油 | CAS号1716-07-0 1,3-二油酸-2-棕榈酸甘油三酯 | CAS号1487-51-0 1-Palmitoyl-3-O... | CAS号22128-35-4 1-O-benzyl-2-O-...

合成工艺路线路线简述

    📜三棕榈酸甘油酯置于thermomyces Lanuginosa Lipase体系中,用 乙醇 用作溶剂,化学反应 24.0H,以8%的收率获得2-单棕榈酸甘油
    参考文献:Monomyristin 和 Monopalmitin 衍生物:作为潜在的抗菌和抗真菌剂的合成和评价
    标题:Monomyristin 和 Monopalmitin 衍生物:作为潜在的抗菌和抗真菌剂的合成和评价
    摘要:在目前的工作中,以市售的肉豆蔻酸和棕榈酸为原料,成功地制备了单酰基甘油衍生物,即 1-单肉豆蔻素,2-单肉豆蔻素和 2-单棕榈酸.1-单肉豆蔻碱化合物是通过肉豆蔻酸乙酯和1,2-O-异亚丙基甘油之间的酯交换反应制备的,该反应是用丙酮保护甘油得到的,然后使用amberlyst-15脱保护.另一方面,2-单酰基甘油衍生物是在疏毛嗜热丝孢菌脂肪酶存在下通过甘油三酯的酶水解制备的.使用傅里叶变换红外 (Ftir) 分光光度计,气相或液相色谱-质谱仪 (Gc-Ms 或 Lc-Ms) 分析合成产物,以及质子和碳核磁共振(1H-和 13C-NMR)光谱仪.发现单肉豆蔻酸具有很高的抗菌和抗真菌活性,而 2-单棕榈酸则完全没有任何活性.与阳性对照相比,1-单肉豆蔻素化合物对金黄色葡萄球菌和聚集放线菌显示出更高的抗菌活性,并且对白色念珠菌具有更高的抗真菌活性.同时,2-Monoryristin 对大肠杆菌表现
    Doi:10.3390/molecules23123141

    海关参考信息

    专利信息


    专利号:US-2025282701-A1
    优先权日:2022-04-22
    标 题:A process for the direct conversion of sugar to value added products
    发明人：MARIMUTHU BANU; SREEKANTAN SREEJITH; KIRALI ARUN ARUNIMA BALACHANDRAN
    权利人:COUNCIL SCIENT IND RES
    摘要:An efficient one step, one pot process of synthesis of value-added products such as diols, monools and/or acids, preferably 1,2-PG from sugars/polysachhrides is disclosed. The process is catalyzed by a bimetallic catalyst supported on alumina and the catalyst is recyclable. The process of synthesis of the catalyst is a simple process and it converts a high % of the substrates to the desired polyols under mild conditions.

    专利号:US-2022370393-A1
    优先权日:2019-10-16
    标 题 :Method and composition for increasing muscle protein synthesis
    发明人：BELLAMINE AOUATEF; GLAB STANISLAW; DURKEE SHANE
    权利人:CAPSUGEL BELGIUM NV
    摘要:A method and composition for increasing muscle protein synthesis in mammals is disclosed. In one embodiment, the mammals are administered a protein building composition comprising at an amino acid derivative including L-carnitine and a nitrogenous organic acid including creatine. In a particular embodiment, the creatine is in an acid resistant capsule delivery form. The ratio of L-carnitine to creatine can be from about 10:1 to about 1:1. The protein building composition can be administered in a monolithic enteric capsule.

    专利号:US-2022370392-A1
    优先权日:2019-10-16
    标 题:Method and Composition for Increasing Muscle Protein Synthesis
    发明人：BELLAMINE AOUATEF; GLAB STANISLAW; DURKEE SHANE
    权利人:BELLAMINE AOUATEF; CAPSUGEL BELGIUM NV
    摘要:A method and composition for increasing muscle protein synthesis in mammals is disclosed. In one embodiment, the mammals are administered a protein building composition comprising at an amino acid component including L-carnitine and a nitrogenous organic acid including creatine. In a particular embodiment, the creatine is in a solution with L-carnitine. The ratio of L-carnitine to creatine can be from about 10:1 to about 1:1. The protein building z composition can be administered in a monolithic enteric capsule.

    专利号:EP-1414419-B1
    优先权日:2001-07-26
    标题:Pharmaceutical formulations comprising a cortisol synthesis inhibitor
    发明人：LJUSBERG BARBRO HELENA; HYLEN SUSANNE VERONICA; FYGE ASA HELEN
    权利人:CORTENDO AB
    摘要:The present invention relates to pharmaceutical compositions comprising ketoconazole or a derivative thereof, one or more low melting point lipid excipients and a sufficient quantity of one or more high melting point lipid excipients to provide a liquid and a solid phase within said composition after heating to 35° C. for 18 hours more particularly to pharmaceutical compositions comprising ketoconazole or a derivative thereof and a lipid excipient, at least 85% by weight of said lipid excipient consisting or one or more low melting point lipids and 1-15% by weight of said lipid excipient consisting of one or more high melting point lipids, polymeric excipients are also described as are the use of these formulations in the treatment of metabolic syndrome and related conditions.

    专利号:CN-117286195-A
    优先权日:2023-10-09
    标题:Application of a native moss in the synthesis of D-lyxose

    专利号:DE-202024104723-U1
    优先权日:2024-08-21
    标题:System for the synthesis of Curcuma Aromatica Salisb. extract and characterization of the properties of the extract

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    主要参考文献

    [参考文献]: Natalia Murataeva, Et Al. Where'S My Entourage The Curious Case Of 2-Oleoylglycerol, 2-Linolenoylglycerol, And 2-Palmitoylglycerol. Pharmacol Res. 2016 Aug;110:173-180.

    合成参考文献


    参考文献:10.1111/nmo.13961
    摘要:Bashashati M, Leishman E, Bradshaw H, Sigaroodi S, Tatro E, Bright T, McCallum R, Sarosiek I. Plasma endocannabinoids and cannabimimetic fatty acid derivatives are altered in gastroparesis: A sex- and subtype-dependent observation. Neurogastroenterol Motil. 2021 Jan;33(1):e13961.
    参考文献:10.1096/fasebj.11.1.9034165
    摘要:Ghosh S, Strum JC, Bell RM. Lipid biochemistry: functions of glycerolipids and sphingolipids in cellular signaling. FASEB J. 1997 Jan;11(1):45–50. doi: 10.1096/fasebj.11.1.9034165.
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