CAS: 136033-55-1; (2S,3R,4S,5S,6R)-2-((2-((2S,5R)-5-((2Ar,3R,4R,5As,7R,9R,11Ar)-4,7-Dihydroxy-2A,5A,8,8-Tetramethyl-9-(((2S,3R,4S,5R)-3,4,5-Trihydroxytetrahydro-2H-Pyran-2-yl)Oxy)Hexadecahydrocyclopenta[a]Cyclopropa[e]Phenanthren-3-yl)-5-Methyltetrahydrofuran-2-yl)Propan-2

该化合物是一种生物活性沙邦素化合物,产自传统药草Astragalus membranaceus,在结构上与Astragaloside IV相似,但由于其独特的淋阳性模式,该化合物具有不同的药理特性.该化合物因其潜在的...

英文名称(2S,3R,4S,5S,6R)-2-((2-((2S,5R)-5-((2Ar,3R,4R,5As,7R,9R,11Ar)-4,7-Dihydroxy-2A,5A,8,8-Tetramethyl-9-(((2S,3R,4S,5R)-3,4,5-Trihydroxytetrahydro-2H-Pyran-2-yl)Oxy)Hexadecahydrocyclopenta[a]Cyclopropa[e]Phenanthren-3-yl)-5-Methyltetrahydrofuran-2-yl)Propan-2
中文名称异黄芪皂苷IV
IUPAC名称(2S,3R,4S,5S,6R)-2-((2-((2S,5R)-5-((2aR,3R,4R,5aS,7R,9R,11aR)-4,7-dihydroxy-2a,5a,8,8-tetramethyl-9-(((2S,3R,4S,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)tetradecahydro-1H,12H-cyclopenta[a]cyclopropa[e]phenanthren-3-yl)-5-methyltetrahydrofuran-2-yl)propan-2-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
其它别名Isoastragaloside Iv; β-D-Glucopyranoside, (3β,6α,16β,20R,24S)-20,24-Epoxy-6,16-Dihydroxy-3-(β-D-Xylopyranosyloxy)-9,19-Cyclolanostan-25-Yl; Inhibit,Inhibitor,Isoastragaloside Iv; Isoastragaloside Iv, 10 Mm In Dmso
CAS编号136033-55-1
MFCD编号:MFCD32694028
分子式:C41H68O14
分子量:784.98
产品CID: 561756
产品分类有机原料 → 脂质和类脂质分子 → 类固醇和类固醇衍生物

相似结构搜索
InChIKey: MSSYPWFHLFBMMP-BWAXJHDDSA-N
InChI=1S/C41H68O14/c1-35(2)24(53-33-29(49)26(46)21(45)17-51-33)9-11-41-18-40(41)13-12-37(5)32(20(44)15-38(37,6)23(40)14-19(43)31(35)41)39(7)…
计算化学: 氢键受体数14.0氢键供体数9.0可旋转键数7.0

MSDS等安全信息

警示词Danger
危险描述H301+H311+H331-
防范说明P261-P264-P270-P271-P280-P301+P310+P330-P302+P352+P312-P361+P364-P403+P233-P405-P501-

合成工艺路线路线简述

在 Sodium Methylate体系中,用甲醇用作溶剂,化学反应 18.0H,以30 Mg的收率获得异黄芪皂苷iv
参考文献:环己烯醇糖苷的合成途径
标题:环己烯醇糖苷的合成途径
摘要:第一种有效的合成方法是对四种类型的环戊烷糖苷,环黄芪醇25-O进行合成.3-O ; 3,6-O-Bis;已经建立了3,25-O-双糖苷,其特征在于ppy介导的,浓度控制的乙酰化和au(i)催化的yu糖基化.通过综合研究,首次确定了环黄芪醇中四个oh的反应序列,并发现了高效去除大的新戊酰基保护基的绕线策略.
Doi:10.1021/acs.Joc.7B00080