CAS: 1204-06-4; 3-(1H-Indol-3-yl)Acrylic Acid

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CAS号110110-37-7 3-(1H-indol-3-y... | CAS号487-89-8 3-吲哚甲醛 | CAS号141-82-2 丙二酸 | CAS号19626-93-8 (E)-methyl 3-(1... | CAS号22948-94-3 N-乙酰基吲哚-3-羧甲醛 | CAS号576-15-8 1-乙酰吲哚 | CAS号87894-44-8 ethyl (E)-3-(1-... | CAS号110110-44-6 cis-3-(β-carbet... | CAS号830-96-6 3-吲哚丙酸(IPA)

Methyl 3-(1H-Indol-3-yl)-Acrylate置于lithium Hydroxide,盐酸体系中,用 水,二乙二醇 用作溶剂,化学反应 0.25H,反应生成3-吲哚丙烯酸
参考文献:Polymer-Assisted Solution-Phase Synthesis Under Combined Ultrasound And Microwave Irradiation: Preparation Of α,β-Unsaturated Esters And Carboxylic Acids,Key Intermediates Of Novel Sigma Ligands
标题:Polymer-Assisted Solution-Phase Synthesis Under Combined Ultrasound And Microwave Irradiation: Preparation Of α,β-Unsaturated Esters And Carboxylic Acids,Key Intermediates Of Novel Sigma Ligands
摘要:The Optimal Conditions To Prepare,-Unsaturated Methyl Esters Via Wittig Reaction Combining Polymer-Assisted Solution-Phase Synthesis (Pasps) Methodology And Simultaneous Ultrasound And Microwave Irradiation Were Established. The Effects Of Temperature,Solvent,And Irradiation Time Were Discussed. Results Clearly Indicated The Superiority Of Combined Ultrasound And Microwave-Assisted Procedure Over Microwave-Assisted Methodology. Moreover,An Efficient Pasps Procedure To Prepare,-Unsaturated Carboxylic Acids Via Tandem Wittig Olefination And Hydrolysis Reaction Was Developed Under Combined Ultrasound And Microwave Irradiation. Generally,A Good Conversion Of Aldehydes To Acids Was Observed. The Optimized Protocols Allowed Us To Quickly Prepare A Small Collection Of Either,-Unsaturated Esters Or Carboxylic Acids,Key Intermediates For The Drug-Discovery Process Of New Sigma Ligands.
Doi:10.1080/00397910902738112

专利信息

专利号:US-6051686-A
优先权日:1992-07-14
标题 :Analogs of parathyroid hormone and parathyroid hormone related peptide: synthesis and use for the treatment of osteoporosis
发明人：KRSTENANSKY JOHN L; NESTOR JR JOHN J; HO TERESA H; VICKERY BRIAN H; BACH CHINH T
权利人:SYNTEX INC
摘要:Synthetic polypeptide analogs of parathyroid hormone PTH, parathyroid hormone related peptide PTHrp, and of the physiologically active truncated homologs and analogs of PTH and PTHrp, in which amino acid residues (22-31) form an amphipathic alpha -helix, said residues (22-31) selected from hydrophilic amino acids (Haa) and lipophilic amino acids (Laa) ordered in the sequence: Haa(Laa Laa Haa Haa)2 Laa and their pharmaceutically acceptable salts are useful for the prophylaxis and treatment of ostoporosis in mammals. Processes for the production of the polypeptides via solid phase and recombinant methods are provided.

专利号:US-5004690-A
优先权日:1983-06-28
标 题 :Ascorbic acid intermediates and process enzymes
发明人：LIGHT DAVID R; RASTETTER WILLIAM H
权利人:GENENTECH INC
摘要:A process for the preparation of 2-keto-L-gulonic acid (2-KLG) from 2,5-diketo-D-gluconic acid (2,5-DKG) using a DNA sequence encoding 2,5-DKG reductase. The 2-KLG is a precursor for the synthesis of ascorbic acid (Vitamin C).

专利号:US-4758514-A
优先权日:1983-06-28
标题:Ascorbic acid intermediates and process enzymes
发明人：LIGHT DAVID R; RASTETTER WILLIAM H
权利人:GENENTECH INC
摘要:2-keto-L-gluonic acid (2-KLG) is prepared from 2,5-diketo-D-gluconic acid (2,5-DKG) using a microorganism containing the enzyme 2,5-DKG reductase produced by an expression plasmid encoding a gene for the enzyme. The product, 2-KLG is a precursor for the synthesis of ascorbic acid (vitamin C).

专利号:HU-202277-B
优先权日:1982-12-24
标题:Process for producing dna sequences and plasmids comprising such sequences, as well as their use for synthesis of interferon

专利号:CN-114026247-B
优先权日:2019-04-26
标 题 :Genes for the synthesis of high molecular weight copolymers

专利号:KR-20160099510-A
优先权日:2016-08-01
标 题:HELICOBACTER PYLORI α-1,3 FUCOSYLTRANSFERASE GENE AND PROTEIN WITH IMPROVED SOLUBLE PROTEIN EXPRESSION AND ACTIVITY, AND THEREOF APPLICATION FOR SYNTHESIS OF α-1,3 FUCOSYLOLIGOSACCHARIDE