CAS: 878194-92-4; 4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)Nicotinonitrile
该化合物是一种丙烯酯衍生物,含有一个有硝酸三烯核心功能的丙烯核心,以及一个和的黄酸盐.该化合物主要用作交叉反应的多种中间体,如铃木-米亚乌拉交配,因为它稳定的双甲酸酯组,有利于高效的保冕-碳联结形成.带式硝酸乙烯组增强了核生殖反应的再活动,使其在制药和农用化学合成中具有价值.其晶状固态可以确保易于处理和储存.该产品高纯度和持续性能使其适合于医药化学和材料科学研究的应用.
- 英文名称4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)Nicotinonitrile
- 中文名称4-(4,4,5,5-四甲基-1,3,2-二氧杂硼烷-2-基)烟腈
- IUPAC名称4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-3-carbonitrile
- 其它别名3-氰吡啶-4-硼酸频哪酯; 3-Cyanopyridine-4-Boronic Acid Pinacol Ester
- CAS编号878194-92-4
- MFCD编号:MFCD09037481
- EINECS号:678-955-3
- 分子式:C12H15BN2O2分子量:230.07
- 产品CID: 1886880
- 产品分类有机原料→分子砌块→芳杂环类化合物→吡啶类化合物
相似化合物
1032358-00-1 1032358-02-3 2223033-72-3物理性质
MSDS等安全信息
上下游产品
CAS号100-54-9 3-氰基吡啶 | CAS号76-09-5 频哪醇 | CAS号874290-89-8 3-氰基吡啶-4-硼酸 | CAS号923012-49-1 5H-pyrido[3,4-c... | CAS号923012-52-6 6-chloropyrido[...合成工艺路线路线简述
- 合成目标产物 3-Cyano-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-yl)Pyridine 主要起始原料 3-Cyanopyridine And Pinacol
- 76-09-5 + 874290-89-8 = 878194-92-4
反应条件:1.1 Reagents: Sulfuric Acid Magnesium Salt (1:1) Solvents: Toluene; Overnight,Rt
标题:Synthesis Of Ortho-Cyanopyridylboronic Acids And Esters Toward Cyano-Functionalized Bipyridines
作者:Cailly,Thomas; Fabis,Frederic; Bouillon,Alexandre; Lemaitre,Stephane; Sopkova,Jana; Et Al
参考文献:Synlett 日期:2006 卷标:(1) 页码:53-56]
76-09-5 + 100-54-9 = 878194-92-4
反应条件:1.1 Reagents: Butyllithium,2,2,6,6-Tetramethylpiperidine Solvents: Tetrahydrofuran,Hexane; Rt -> -10 °C; 2 Min,-10 °C; 10 Min,-10 °C; -10 °C -> -78 °C1.2 Reagents: Triisopropyl Borate; 2 Min,-78 °C; 5 Min,-78 °C1.3 Solvents: Tetrahydrofuran; 5 Min,-78 °C; Overnight,-78 °C -> Rt1.4 Reagents: Acetic Acid1.5 2 H,Rt1.6 -
标题:One-Pot Synthesis Of New Aza- And Diaza-Aminophenanthrenes
作者:Rochais,Christophe; Yougnia,Rodrigue; Cailly,Thomas; Sopkova-De Oliveira Santos,Jana; Rault,Sylvain; Et Al
参考文献:Tetrahedron 日期:2011 卷标:67(32) 页码:5806-5810
📜3-氰基吡啶置于2,2,6,6-四甲基哌啶,盐酸,正丁基锂,Magnesium Sulfate体系中,用 四氢呋喃,甲苯 作为反应溶剂,化学反应 12.5H,反应生成 3-氰嘧啶-4-硼酸频哪酯
参考文献:Synthesis Ofortho-Cyanopyridylboronic Acids And Esters Toward Cyano-Functionalized Bipyridines
标题:Synthesis Ofortho-Cyanopyridylboronic Acids And Esters Toward Cyano-Functionalized Bipyridines
摘要:这项工作描述了邻氰基吡啶硼酸和酯的合成.评估了它们与吡啶卤化物在铃木交叉偶联反应中的反应性,结果表明氰基吡啶硼酸酯似乎比其对应的酸更稳定.这些酯使我们能够合成新的氰基双吡啶体系.
DOI:10.1055/s-2005-922772
海关参考信息
- 2905122000-异丙醇
2905143000-叔丁醇
2905310000-1,2-乙二醇
2905320000-1,2-丙二醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
参考标题:Amyloid Targeting Agents And Methods Of Using The Same摘要:Provided Herein Is The Design And Synthesis Of Novel Molecular Rotor Fluorophores Useful For Detection Of Amyloid Or Amyloid Like Proteins. The Fluorophores Are Designed To Exhibit Enhanced Fluorescence Emission Upon Associating With Amyloid Or Amyloid Like Proteins As Compared To Unbound Compound. Also Disclosed Herein Are Methods For Treating Diseases Associated With Amyloid Or Amyloid Like Proteins.
合成参考文献
参考文献:10.1055/s-2005-922772
摘要:Rault S, Cailly T, Fabis F, Bouillon A, Lemaître S, Sopkova J, de Santos O. Synthesis ofortho-Cyanopyridylboronic Acids and Esters toward Cyano-Functionalized Bipyridines. Synlett. 2006;(1):0053–6. doi: 10.1055/s-2005-922772.
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