CAS: 571-58-4; 1,4-Dimethylnaphthalene

该化合物是氯化萘家族的有机化合物,其特点是其结构,由1和4位置上的两个甲基组组成,其结构为氯化萘脊椎,在1和4位置上有两组.该化合物一般无色,在室内温度下无色,不粉黄液体或固体,具有典型的芳香味,在水中相对不溶解,但在乙醇和乙醇等有机溶剂中可溶解. 1,4-二甲基甲二烷因其稳定性和对氧化的耐受性而闻名,因此在各种应用中有用,包括作为一种溶剂和其他有机化合物的合成.此外,还研究了其在染料生产中和某些工业工艺中的潜在用途.安全考虑因素包括其潜在的刺激效应和避免接触的适当处理的必要性.

结构式图片

相似化合物

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欧盟法规

统一分类与标签ECHA物质ECHA物质工作场所安全标识要求C&L通报REACH预注册废弃物危险特性清单

上下游产品

CAS号4705-93-5 1,4-Epoxynaphth... | CAS号42409-86-9 1,2-bis-(4-meth... | CAS号5261-50-7 1-氯甲基-4-甲基萘 | CAS号83731-53-7 r,t-1,4-dimethy... | CAS号35461-84-8 1,4-dimethylnap... | CAS号97585-87-0 (4-methylnaphth... | CAS号18801-77-9 5-METHYL-2-FURY... | CAS号118-92-3 邻氨基苯甲酸 | CAS号90-12-0 1-甲基萘 | CAS号605-70-9 1,4-萘二甲酸 | CAS号33738-48-6 4-甲基-1-萘醛 | CAS号49675-07-2 acetic acid-(4-... | CAS号35461-84-8 1,4-dimethylnap... | CAS号4488-40-8 4-甲基-1-萘甲酸 | CAS号14108-89-5 5,8-dimethyl-1,... | CAS号14108-88-4 Naphthalene,1,2... | CAS号2717-33-1 5,8-dimethyl-1,... | CAS号87-87-6 四氯氢醌 | CAS号112740-50-8 2,3,5,6-tetrach...

合成工艺路线路线简述

    📜山道年置于锌体系中,化学反应生成 1,4-二甲基萘
    参考文献:Cannizzaro; Carnelutti,Gazzetta Chimica Italiana,1882,Vol. 12,P. 414
    标题:Cannizzaro; Carnelutti,Gazzetta Chimica Italiana,1882,Vol. 12,P. 414

    海关参考信息

    专利信息


    专利号:US-2003162992-A1
    优先权日:2001-12-14
    标 题 :Preparation of intermediates useful in the synthesis of antiviral nucleosides
    发明人:WATANABE KYOICHI A; DU JINFA
    摘要:The present invention is an efficient process for the manufacture of α-acyloxyacetaldehyde, a key intermediate in the synthesis of 1,3-oxathiolane and 1,3-dioxolane nucleosides.

    专利号:US-4460786-A
    优先权日:1980-07-10
    标题 :Process for the selective addition of a compound having an activated carbon atom onto a substituted conjugated diene
    发明人:MOREL DIDIER
    权利人:RHONE POULENC IND
    摘要:The selective addition of a compound having an activated carbon atom onto the carbon atom in the 4-position of a buta-1,3-diene carrying a hydrocarbon substituent on the carbon atom in the 2-position is achieved by reacting the compound having the activated carbon atom with the buta-1,3-diene carrying the hydrocarbon substituent in water or in an aqueous-alcoholic mixture in the presence of a catalyst which consists of at least one water-soluble phosphine and at least one rhodium compound, the catalyst being in solution in the water or aqueous alcoholic mixture. The products obtained are useful as precursors of intermediates for the synthesis of vitamins and perfumes.

    专利号:US-8957260-B2
    优先权日:2011-02-07
    标题 :Process for the oxidation of mesitol
    发明人:WEYRAUCH JAN PHILIPP; WEIS MARTINE; TELES JOAQUIM HENRIQUE; EBEL KLAUS; DEGLMANN PETER
    权利人:WEIS MARTINE; TELES JOAQUIM HENRIQUE; EBEL KLAUS; DEGLMANN PETER; WEYRAUCH VIVIEN ELLINOR; WEYRAUCH GUNHILD; BASF SE
    摘要:The invention relates to a process for the oxidation of mesitol with singlet oxygen, which is released from hydrogen peroxide, this release taking place in the presence of a bismuth compound as catalyst. In the process, 2,4,6-trimethylquinol is formed in high yield and selectivity as product, which can be used in further reactions for the synthesis of vitamins and in particular of vitamin A and vitamin E.

    专利号:US-4594460-A
    优先权日:1984-03-22
    标题:Process for selective C-alkylation of phenols
    发明人:MIGNANI GERARD; MOREL DIDIER
    权利人:RHONE POULENC SANTE
    摘要:Substituted phenols of formula ##STR1## in which R 1 is in an ortho or para position relative to the phenol function and denotes ##STR2## R 2 denotes an acyclic radical optionally substituted by alkyl, hydroxy, alkoxycarbonyl, cyano or formyl, or a phenyl or naphthyl radical, and R denotes hydrogen or 1 to 4 substituents chosen from halogen, OH optionally in the form of ether or ester, alkyl, NO 2 , CHO optionally in the form of acetal, CH 3 CO--, C 6 H 5 CO--, NH 2 , alkylamino, dialkylamino or alkoxycarbonyl, it being understood that 2 symbols R may form with the phenyl nucleus a condensed aromatic ring, which comprises reacting a butadiene of formula ##STR3## with a phenol for formula ##STR4## in water in the presence of a rhodium-based catalyst, a water-soluble phosphine and optionally an inorganic or organic base. The products of formula (I) are intermediates for the synthesis of vitamin E, antioxidants, perfumes or insecticides.

    专利号:US-4950368-A
    优先权日:1989-04-10
    标 题 :Method for paired electrochemical synthesis with simultaneous production of ethylene glycol
    发明人:WEINBERG NORMAN L; GENDERS JOHN D; MAZUR DUANE J
    权利人:ELECTROSYNTHESIS CO INC; SKA ASS
    摘要:Paired electrochemical synthesis reactions in which ethylene glycol is formed at the cathode of a membrane divided cell at high concentrations and current efficiencies, up to 99 percent. Simultaneously, a compatible process is also conducted at the anode of the same electrochemical cell by reacting indirectly generated anode products with organic substrates to form secondary products, such as polybasic acids. The process is especially advantageous in that such secondary products, where appropriate can be further reacted with the ethylene glycol prepared from the catholyte of the same cell to form useful tertiary products, especially polyesters like polyethylene terephthalate. Mole ratios of ethylene glycol and polybasic acid can be controlled through selective use of regeneratable redox reactant.

    专利号:US-7973109-B2
    优先权日:2007-03-29
    标 题 :Crosslinked type layered metal phosphonate compound, production process therefor, non-crosslinked type layered metal phosphonate compound, production process therefor, as well as stock solution
    发明人:OGATA SHIN-ICHI; FUKUSHIMA YOSHIAKI; KAWASUMI MASAYA
    权利人:TOYOTA CHUO KENKYUSHO KK
    摘要:A process for producing a crosslinked type or non-crosslinked type layered metal phosphonate compound including a reaction step of reacting two or more members selected from organic diphosphonic acids or monophosphonic acids, or derivatives thereof having predetermined conditions and a metal source capable of forming an ion of a hexacoordinate metal atom as a central atom (M) of a metal oxide octahedron upon reaction under the presence of a sulfuric acid catalyst, a crosslinked or non-crosslinked metal phosphonate compound obtained by the process, as well as a stock solution used for the synthesis of the crosslinked or non-crosslinked type layered metal phosphonate compound described above.

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: A A Toropov, Et Al. Qspr Modeling Of Octanol/water Partition Coefficient For Vitamins By Optimal Descriptors Calculated With Smiles. Eur J Med Chem. 2008 Apr;43(4):714-40.
    [参考文献]: A Kilanowicz, Et Al. Disposition And Metabolism Of 1,4-Dimethylnaphthalene In Rat. Int J Occup Med Environ Health. 2000;13(4):325-34.
    [参考文献]: Anne Tndervik, Et Al. Ralstonia Sp. U2 Naphthalene Dioxygenase And Comamonas Sp. Js765 Nitrobenzene Dioxygenase Show Differences In Activity Towards Methylated Naphthalenes. J Biosci Bioeng. 2012 Feb;113(2):173-8.
    [参考文献]: D E Hibbs, Et Al. An Aqueous Concentration Model For Riverine Spills. J Hazard Mater. 1999 Jan 1;64(1):37-53.
    [参考文献]: D S Malament, Et Al. Inhibition Of Dmba Carcinogenesis Of Hamster Buccal Pouch By Phenanthrene And Dimethylnaphthalene. Carcinogenesis. 1981;2(8):723-9.

    合成参考文献


    摘要:Toyota, S.; Iwanaga, T., Science of Synthesis, (2010) 45, 774.
    摘要:Toyota, S.; Iwanaga, T., Science of Synthesis, (2010) 45, 761.
    摘要:Dai, X.; Shi, F., Science of Synthesis: Catalytic Reduction in Organic Synthesis, (2017) 1, 143.
    参考文献:10.1007/s11103-010-9607-6
    摘要:Campbell MA, Gleichsner A, Alsbury R, Horvath D, Suttle J. The sprout inhibitors chlorpropham and 1,4-dimethylnaphthalene elicit different transcriptional profiles and do not suppress growth through a prolongation of the dormant state. Plant Mol Biol. 2010 May;73(1-2):181–9. doi: 10.1007/s11103-010-9607-6.
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