CAS: 5632-15-5; 2-(Bromomethyl)Quinoline

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CAS号1780-17-2 2-喹啉基甲醇 | CAS号91-63-4 2-甲基喹啉 | CAS号94-36-0 过氧化苯甲酰 | CAS号4377-41-7 2-(氯甲基)喹啉 | CAS号5470-96-2 2-喹啉甲醛 | CAS号613-53-6 2-三溴甲基喹啉 | CAS号19575-07-6 喹啉-2-羧酸甲酯 | CAS号63430-79-5 1,2,3,4-四氢喹啉-2-羧酸甲酯 | CAS号53867-81-5 2-(二溴甲基)喹啉 | CAS号107813-50-3 2-[(4-nitrophen... | CAS号5760-20-3 2-喹啉甲胺 | CAS号4377-41-7 2-(氯甲基)喹啉 | CAS号14068-28-1 2-(喹啉-2-基)乙腈 | CAS号284477-00-5 2-(喹啉-2-基)乙酸 | CAS号93-10-7 喹哪啶酸 | CAS号5100-57-2 2-(喹啉-2-基)乙酸乙酯 | CAS号123761-12-6 3-(2-喹啉基)-DL-丙氨酸 | CAS号136694-18-3 3-(3-(叔丁基硫基)-1-... | CAS号136668-42-3 喹夫拉朋

过氧化苯甲酰置于n-溴代丁二酰亚胺(Nbs),氢溴酸体系中,用 四氯化碳 作为反应溶剂,以12.6%的收率获得产物2-溴甲基喹啉
参考文献:Amino Acid Analogs As Cck Antagonists
标题:Amino Acid Analogs As Cck Antagonists
摘要:揭示了作为肥胖,胃酸过多,胃泌素依赖性肿瘤治疗剂或抗精神病药物的新型非天然二肽类化合物.此外,这些化合物还是抗焦虑剂和抗溃疡剂.这些化合物是用于预防慢性治疗或使用尼古丁,安定,酒精,可卡因,咖啡因和阿片类药物戒断反应的药物.这些化合物还可用于治疗和/或预防恐慌发作.还公开了使用这些二肽类化合物的药物组合物和治疗方法,以及用于制备它们的过程和在制备中有用的新型中间体.该发明的另一个特点是使用这些化合物制备诊断组合物.

专利信息

专利号:US-6723853-B2
优先权日:2001-08-27
标 题 :Intermediates and methods of preparation of intermediates in the enantiomeric synthesis of (20R)homocamptothecins and the enantiomeric synthesis of (20R)homocamptothecins
发明人：CURRAN DENNIS P; GABARDA ANA E
权利人:UNIV PITTSBURGH
摘要:A method of synthesizing a compound having the formula: n from a compound having the formula: n wherein R 1 is hydrogen, fluorine, chlorine or SiR 5 R 6 R 7 , wherein R 5 , R 6 , and R 7 are independently the same or different an alkyl group or an aryl group, R 2 is an alkyl group, R 3 is a protecting group, R 4 is an alkyl group, an allyl group, a propargyl group —CO 2 H, or a benzyl group, R 8 is —CO 2 R 10 , wherein R 10 is an alkyl group or an aryl group, X 1 is OH and X 2 is H, includes the step of exposing compound (III) to at least one of an organic acid or an inorganic acid. A compound has the general formula (III).

专利号:US-2003073840-A1
优先权日:2001-08-27
标 题 :Intermediates and methods of preparation of intermediates in the enantiomeric synthesis of (20R)homocamptothecins and the enantiomeric synthesis of (20R)homocamptothecins

专利号:WO-03018559-A2
优先权日:2001-08-27
标 题 :Intermediates and preparation thereof for the enantioselective synthesis of (20r) homocamptothecins

专利号:RU-2037481-C1
优先权日:1989-10-27
标 题:Derivatives of substituted benzoylbenzene-, biphenyl or 2-oxazolealkanoic acid or their pharmacologically acceptable salts, and a method of their synthesis

专利号:US-5919797-A
优先权日:1996-04-24
标题:Halogenated naphthyl methoxy piperidines for mapping serotonin transporter sites
发明人：GOODMAN MARK M; FARAJ BAHJAT
权利人:UNIV EMORY
摘要:Halogenated naphthyl methoxy piperidines having a strong affinity for the serotonin transporter are disclosed. Those compounds can be labeled with positron-emitting and/or gamma emitting halogen isotopes by a late step synthesis that maximizes the useable lifeterm of the label. The labeled compounds are useful for localizing serotonin transporter sites by positron emission tomography and/or single photon emission computed tomography.