CAS: 50868-73-0; 2-Methoxy-6-Methylaniline

该化合物是一种芳香的含汞,其特点是,一种甲基氧基(-OCH3)和甲基(-CH3)同时附于苯环,并附于一个苯环;甲氧基组位于与氨基组(-NH2)相对的正方位,而甲基组处于元值位置;该化合物一般是无色的,可粉黄的黄色液体或固体,视其纯度和温度而定;在乙醇和醚等有机溶剂中溶解,但由于其湿性芳性结构而在水中溶解性有限.2-Methoxy-6-甲基碘线用于各种用途,包括作为染料,药物和农用化学品合成的中间体.然而,必须谨慎地处理该物质,因为芳酸氨可能会对健康造成危害,包括潜在的致癌效应.在实验室或工业环境中与该化合物合作时,应当注意适当的安全措施.

结构式图片

欧盟法规

ECHA物质C&L通报

上下游产品

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合成工艺路线路线简述

    间甲基苯甲醚置于盐酸,二硫化碳,氯磺酸,Sodium Hydroxide,氯仿,五氯化磷,硫酸,硝酸,Tin(Ll) Chloride体系中,化学反应生成 2-甲氧基-6-甲基苯胺
    参考文献:Haworth; Lapworth,Journal Of The Chemical Society,1923,Vol. 123,P. 2989
    标题:Haworth; Lapworth,Journal Of The Chemical Society,1923,Vol. 123,P. 2989

    海关参考信息

    专利信息


    专利号:US-4806687-A
    优先权日:1986-04-02
    标题 :Catalytic hydrodesulfurization of ortho-aminobenzylsulfides
    发明人:BALTHAZOR TERRY M; TREMONT SAMUEL J
    权利人:MONSANTO CO
    摘要:Ortho-alkylanilines are prepared by catalytic hydrodesulfurization of ortho-aminobenzyl sulfides using a cobalt-molybdenum oxide catalyst. For example, 2-methyl-6-trifluoromethylaniline is prepared by catalytic hydrodesulfurization of 3-trifluoromethyl-2-aminobenzyl sulfides. The substituted anilines prepared by the method of this invention are useful as intermediates in the synthesis of compounds shown to have herbicidal activity.

    专利号:EP-0051792-A1
    优先权日:1980-11-08
    标 题 :Derivatives of hydroxamic-acid esters, process for their preparation and their use as herbicides
    发明人:FUEHRER WOLFGANG DR; STETTER JOERG DR; EUE LUDWIG DR; SCHMIDT ROBERT RUDOLF DR
    权利人:BAYER AG
    摘要:Hydroxamic acid derivatives of the formula in which Y represents oxygen or sulfur, R¹ represents hydrogen, alkyl or alkoxy, R² represents hydrogen, alkyl, alkoxy or halogen, R³ represents hydrogen, alkyl, alkoxy or halogen, R < 4> represents hydrogen or alkyl, R <5> represents alkyl, alkenyl, alkynyl or alkoxyalkyl, R <6> represents hydrogen, alkyl, alkenyl, alkynyl or alkoxyalkyl or R <4> and R <5> together represent one Alkylene chain, or R 5 and R 6 together represent an alkylene chain, provided Y is oxygen and Z is halogen, a process for their preparation and their use as herbicides. N-phenylglycine derivatives of the formula in which Y, R¹, R², R³, R <4>, R <5> and R <6> have the meanings given above, several processes for their preparation and their use as intermediates for the synthesis of the substances of formula (I).

    专利号:US-2013178413-A1
    优先权日:2010-09-21
    标题 :Hcv ns3 protease inhibitors
    发明人:MCCAULEY JOHN A; LIVERTON NIGEL J; RUDD MICHAEL T; GILBERT KEVIN F; FERRARA MARCO; SUMMA VINCENZO; CRESCENZI BENEDETTA
    权利人:MCCAULEY JOHN A; LIVERTON NIGEL J; RUDD MICHAEL T; GILBERT KEVIN F; FERRARA MARCO; SUMMA VINCENZO; CRESCENZI BENEDETTA
    摘要:The present invention relates to macrocyclic compounds of formula I that are useful as inhibitors of the hepatitis C virus (HCV) NS3 protease, their synthesis, and their use for treating or preventing HCV infections.
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    主要参考文献

    [参考文献]: Jana Sopková-De Oliveira Santos, Et Al. 7-Methoxy-1H-Indazole, A New Inhibitor Of Neuronal Nitric Oxide Synthase. Acta Crystallogr C. 2002 Nov;58(Pt 11):O688-90.

    合成参考文献


    参考文献:10.1007/s12010-023-04771-9
    摘要:Wei L, Fan L, Yang C, Jin M, Osei R. Analysis of Bioactive Compounds Produced by Bacillus mojavensis ZA1 and Their Antagonistic Effect on Colletotrichum coccodes by GC-MS. Appl Biochem Biotechnol. 2024 Aug;196(8):4914–33. doi: 10.1007/s12010-023-04771-9.
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