CAS: 38428-14-7; Isobutyl 2-Isobutoxyquinoline-1(2H)-Carboxylate

该化合物是有机化合物,其特点是结构复杂,结构复杂,包括一个quinoring环系统.该化合物具有一个碳苯丙酸功能组,表明它是酯,代之以一个2-甲基丙基组和一个2-甲基丙基组.这些烷基组的存在助长了其疏水性,有可能影响其在有机溶剂而不是水中的溶解性.该物质因其生物活动而闻名为quinomity,往往表现出抗微生物或抗震波等特性.该化合物的分子结构表明,它可能参与各种典型的酯化学反应,包括水解和转基因.其具体应用和再活性将取决于其使用环境,特别是在药品或农业化学品中,因为其治疗潜力往往会受到探索.应当观察安全性和处理预防措施,因为所有化学物质都具有潜在的毒性或再活性.

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    专利信息


    专利号:WO-0100609-A1
    优先权日:1999-06-29
    标题:Method for synthesis of n-homocysteine thiolactonyl retinamide
    发明人:KAZIMIR MICHAEL; WILSON RAY E II
    权利人:UNIV BAYLOR; KAZIMIR MICHAEL; WILSON RAY E II
    摘要:The present invention describes methods of synthesis for N-homocysteine thiolactonyl retinamide (thioretinamide), a compound that has anticancer and antiatherogenic properties. The present invention further describes methods for the synthesis of N-homocysteine thiolactonyl retinamido cobalamin (thioretinaco), a compound that has potential anticancer, antineoplastic, antiviral, and antiatherogenic properties.

    专利号:US-2019177392-A1
    优先权日:2014-09-23
    标 题 :Synthesis of glp-1 peptides
    发明人:PENIAS NAVON SHARON; NAVEH SHIRLY; VASILEIOU ZOI; BARLOS KONSTANTINOS
    权利人:NOVETIDE LTD
    摘要:Disclosed are processes for the synthesis of GLP-1 peptides, such as liraglutide and semaglutide, and a process for purifying liraglutide.

    专利号:US-5880295-A
    优先权日:1994-02-16
    标 题 :Process for the preparation of diamine intermediates useful in the synthesis of HIV protease inhibitors
    发明人:KALTENBACH III ROBERT FRANK
    权利人:DU PONT PHARM CO
    摘要:The present invention provides a process for the preparation of compounds of formula (V) below, and analogs thereof, which are useful as intermediates for the synthesis of HIV protease inhibitors, including cyclic ureas. ##STR1##

    专利号:US-6287818-B1
    优先权日:2000-04-25
    标 题 :Method for synthesis of N-homocysteine thiolactonyl retinamido cobalamin and uses thereof
    发明人:KAZIMIR MICHAL; WILSON II F RAY
    权利人:UNIV BAYLOR
    摘要:The present invention describes methods for the synthesis of N-homocysteine thiolactonyl retinamido cobalamin (thioretinaco), a compound that has potential anticancer, antineoplastic, antiviral, and antiatherogenic properties.

    专利号:US-6723843-B2
    优先权日:1996-08-26
    标题:Oligosaccharide synthesis
    发明人:TOTH ISTVAN; DEKANY GYULA; KELLAM BARRY
    权利人:ALCHEMIA PTY LTD
    摘要:The invention provides a system for solid-phase synthesis of oligosaccharides, based on the discovery that a 2-substituted-1,3-dioxocycloalkyl linker group of general formula (I) can be used to couple saccharide groups of both the O-glycoside and N-glycoside type to a polymer support. The invention provides reagents, reagent kits and methods for solid-phase oligosaccharide synthesis.

    专利号:US-7160856-B2
    优先权日:1997-04-16
    标 题 :α-O-linked glycoconjugates, methods of preparation and uses thereof
    发明人:DANISHEFSKY SAMUEL J; SAMES DALIBOR; HINTERMANN SAMUEL; CHEN XIAO TAO; SCHWARZ JACOB B; GLUNZ PETER; RAGUPATHI GOVINDASWAMI; LIVINGSTON PHILIP O; KUDUK SCOTT; WILLIAMS LAWRENCE
    权利人:SLOAN KETTERING INST CANCER
    摘要:The present invention provides novel alpha-O-linked glycoconjugates such as alpha-O-linked glycopeptides, as well convergent methods for synthesis thereof. The general preparative approach is exemplified by the synthesis of the mucin motif commonly found on epithelial tumor cell surfaces. The present invention further provides compositions and methods of treating cancer using the alpha-O-linked glycoconjugates.

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    主要参考文献

    参考标题: Methods, Processes And Intermediates For Preparing Chroman Compounds Procédés, Processus Et Intermédiaires Pour La Préparation De Composés Chromane
    摘要:This Disclosure Describes An Economical And Scalable Method And Process To Synthesize The Calcium Sensing Receptor (Casr) Modulating Agent 2-Methyl-5-((2R,4S)-2-((((R)-1-(Naphthalen-1-Yl)Ethyl)Amino)Methyl)Chroman-4-Yl)Benzoic Acid, Its Intermediates And Pharmaceutically Acceptable Salts Therefor. Uses Of Said Intermediates For Synthesis Of Compounds Which May Be Intermediates To The Synthesis Of 2-Methyl-5-((2R,4S)-2-((((R)-1-(Naphthalen-1-Yl)Ethyl)Amino)Methyl)Chroman-4-Yl)Benzoic Acid Are Also Described Herein.

    合成参考文献


    参考文献:10.1016/j.bmcl.2009.12.078
    摘要:Sathe M, Derveni M, Allen M, Cullen DC. Use of polystyrene-supported 2-isobutoxy-1-isobutoxycarbonyl-1,2-dihydroquinoline for the preparation of a hapten–protein conjugate for antibody development. Bioorganic & Medicinal Chemistry Letters. 2010 Mar;20(5):1792–5. doi: 10.1016/j.bmcl.2009.12.078.
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