CAS: 3670-68-6; 3-Piperidin-1-Yl-1-(4-Propoxyphenyl)Propan-1-One

英文名称3-Piperidin-1-Yl-1-(4-Propoxyphenyl)Propan-1-One
中文名称丙哌卡因
IUPAC名称3-Piperidino-4'-propoxypropiophenone
其它别名Propiophenone,3-piperidino-4'-propoxy- (6CI,8CI); 1-Piperidino-3-p-propoxyphenylpropan-3-one; 3-Piperidino-4'-propoxypropiophenone; Exotancain; Ophthafalicain; Propip°Caine
CAS编号3670-68-6
MFCD编号:MFCD00699374
FDA UNII编号:U09698V56W
分子式:C17H25NO2分子量:275.389
产品CID: 1376280
产品分类有机原料 → 有机氧化合物

相似结构搜索
产品信息参考;
InChIKey: STHAHFPLLHRRRO-UHFFFAOYSA-N
1S/C17H25NO2/c1-2-14-20-16-8-6-15(7-9-16)17(19)10-13-18-11-4-3-5-12-18/h6-9H,2-5,10-14H2,1H3
计算化学: 氢键受体数3.0氢键供体数*可旋转键数7.0

物理性质

沸点411.4 °C at 760mmHg
闪点202.6 °C
密度1.027g/cm3
PSA:29.54
LogP:3.472
折射率1.52
外观形态固体-粉末
储存条件Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

MSDS等安全信息

上下游产品

CAS号80919-63-7 3-chloro-1-(4-p... | CAS号50-00-0 甲醛 | CAS号6091-44-7 哌啶盐酸盐 | CAS号5736-86-7 4'-丙氧基乙酰苯

合成工艺路线路线简述

📜3-Chloro-1-(4-Propoxy-Phenyl)-Propan-1-One置于甲醇,Potassium Acetate体系中,化学反应生成丙哌卡因
参考文献:Profft Et Al.,Journal Fur Praktische Chemie (Leipzig 1954),1954,Vol. <4> 1,P. 57,75
标题:Profft Et Al.,Journal Fur Praktische Chemie (Leipzig 1954),1954,Vol. <4> 1,P. 57,75

海关参考信息

2902600000-乙苯
2905121000-正丙醇
2912110000-甲醛
2912120000-乙醛
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

专利信息

专利号:CN-109180606-A
优先权日:2018-09-30
标题 :Synthesis of a class of optically active Î²-amino ketones

专利号:US-7993390-B2
优先权日:2002-02-08
标题:Implantable or insertable medical device resistant to microbial growth and biofilm formation
发明人：MILLER KATHLEEN M; BUCAY-COUTO WEENNA; LI JIANMIN
权利人:BOSTON SCIENT SCIMED INC
摘要:Disclosed are implantable or insertable medical devices that provide resistance to microbial growth on and in the environment of the device and resistance to microbial adhesion and biofilm formation on the device. In particular, the invention discloses implantable or insertable medical devices that comprise at least one biocompatible matrix polymer region, an antimicrobial agent for providing resistance to microbial growth and/or a microbial adhesion/biofilm synthesis inhibitor for inhibiting the attachment of microbes and the synthesis and accumulation of biofilm on the surface of the medical device. Also disclosed are methods of manufacturing such devices under conditions that substantially prevent preferential partitioning of any of said bioactive agents to a surface of the biocompatible matrix polymer and substantially prevent chemical modification of said bioactive agents.

专利号:CN-109180606-B
优先权日:2018-09-30
标题 :Synthesis method of beta-aminoketone with optical activity

其他信息查阅

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品牌试剂参考报价(招募中)

实用工具

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

主要参考文献

1. Schmidt AC. Solid-state characterization of falicaine hydrochloride and isomorphic dyclonine hydrochloride. Part IV. Crystal polymorphism of local anaesthetic drugs. Eur J Pharm Sci. 2005 Jul-Aug;25(4-5):407-16. doi: 10.1016/j.ejps.2005.04.001.

合成参考文献

摘要:Arzneimittel-Forschung. Drug Research., 5(559), 1955 []
摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198
摘要:KUSTNER W. [Falicain, a new surface anesthetic in otorhinolaryngology]. Z Arztl Fortbild (Jena). 1954 Jan 15;48(2):67.
参考文献:10.1002/ardp.19542870302
摘要:BRAUNIGER H, RAUDONAT HW. [Quantitative determination of cleavage products of 3-piperidino-4'-propoxypropiophenone (falicain)]. Arch Pharm Ber Dtsch Pharm Ges. 1954;287(3):109–16. doi: 10.1002/ardp.19542870302.
摘要:BRAUNIGER H, RAUDONAT HW. [Paper electrophoresis of the solutions of beta-piperidinethyl-p-propoxyphenylketone (falicain)]. Pharm Zentralhalle Dtschl. 1954 Apr;93(4):136–8.