CAS: 2210-79-9; 2-((O-Tolyloxy)Methyl)Oxirane

上下游产品

CAS号95-48-7 邻甲酚 | CAS号106-89-8 环氧氯丙烷 | CAS号25772-91-2 1-chloro-3-(2-m... | CAS号4549-72-8 sodium,2-methyl... | CAS号584-08-7 碳酸钾 | CAS号110-89-4 六氢吡啶 | CAS号3132-64-7 环氧溴丙烷 | CAS号25772-91-2 1-chloro-3-(2-m... | CAS号59-47-2 3-(2-甲基苯氧基)-1,2-丙烷二醇 | CAS号39144-34-8 1-甲氧基-3-(2-甲基苯氧... | CAS号122-60-1 环氧丙基苯基醚 | CAS号95-48-7 邻甲酚 | CAS号108-95-2 苯酚 | CAS号101693-39-4 (2R)-2-[(2-METH... | CAS号206126-37-6 (2R)-3-tolyloxy...

1-Chloro-3-(2-Methylphenoxy)Propan-2-Ol置于sodium Hydride体系中,用 正己烷,乙酸乙酯 用作溶剂,化学反应 0.08H,以231 Mg的收率获得邻甲苯缩水甘油醚
参考文献:[14C]-标记的脂肪族和芳香族醇缩水甘油醚和甘油醚的合成
标题:[14C]-标记的脂肪族和芳香族醇缩水甘油醚和甘油醚的合成
摘要:[14C]-标记的缩水甘油醚和相应的甘油醚的合成描述了单官能化合物 1-十二醇和邻甲酚和双官能化合物 4,4'-二羟基-3,3',5,5'-四甲基联苯和 1,6-己二醇.该合成基于醇与 [u-14C]-表氯醇 (1) 之间的反应.使用氢氧化钠将芳香族化合物转化为相应的缩水甘油醚,使用氯化锡 (Iv) 作为催化剂将脂肪族化合物转化为相应的缩水甘油醚.因此,放射性标记的缩水甘油醚的收率在 50-80% 之间,化学纯度 >92%,放射化学纯度 >95%.缩水甘油醚的比活性对于单官能化合物约为 0.2 Mci/mmol,对于双官能化合物约为 0.4 Mci/mmol.
Doi:10.1002/(Sici)1099-1344(200002)43:2<147::Aid-Jlcr301>3.0.Co;2-H

专利信息

专利号:US-10968308-B2
优先权日:2017-11-07
标 题 :Preparation method of epoxy compound having alkoxysilyl group, epoxy compound having alkoxysilyl group, composition comprising the same, and use thereof
发明人：CHUN HYUN AEE; KIM YUN JU; PARK SOOK YEON; PARK SU JIN
权利人:KOREA INST IND TECH
摘要:Provided are a preparation method of an epoxy compound having an alkoxysilyl group in which an increase in the epoxy equivalent weight (EEW) of the epoxy compound is minimized because alkoxysilylation occurs through a simple one-step reaction using a hydroxyl group formed during the synthesis of the epoxy compound, an epoxy compound having an alkoxysilyl group prepared by the method, a composition comprising the same, and a use thereof. The method includes the reaction of an epoxy compound having a hydroxyl group with an isocyanate alkoxysilane in the presence of amine-based base catalyst, wherein the epoxy compound having an alkoxysilyl group has a mole ratio of [epoxide group]:[alkoxysilyl group] of n:1 ranging from 2:1 to 10:1, and an EEW increase of the epoxy compound having an alkoxysilyl group is less than 260/n. The epoxy compound has good physical properties when being cured.

专利号:US-9790398-B2
优先权日:2013-02-08
标 题 :Synthesis of polyurethane polymers via copper azide-alkyne click chemistry for coatings, adhesives, sealants and elastomer applications
发明人：CARTER NEIL; MARTIN IAN; COWARD ALEXANDER; GATRELL MARK; BYRNE MICHAEL; CULLEN JOHN E; CORMACK PETER
权利人:SIKA TECH AG
摘要:The present application is directed at the reaction product of an azide compound having two or more azide groups attached thereto and an alkyne compound having two or more alkyne groups attached thereto, wherein the azide and alkyne groups react in a 1,3-dipolar cyclo addition to form 1,4-disubstituted triazols and wherein the azide or alkyne compound or both include —O—(Câ•?O)—NR— functional groups. The reaction products can be used as coatings, such as for flat roofs, sealants, adhesives and in elastomer applications. Methods for producing the reaction products as well as substrates including a coating of the reaction product are also disclosed.

专利号:US-11326018-B2
优先权日:2016-08-19
标 题:Process for the synthesis of polyoxazolidinone compounds
发明人：WEBER ANNA; RANGHEARD CLAUDINE; KESSLER MICHAEL; LEITNER WALTER; Gürtler Christoph; KOOPMANS CARSTEN; MÃœLLER THOMAS ERNST
权利人:COVESTRO DEUTSCHLAND AG
摘要:A method for the production of polyoxazolidinone compounds, comprising the step of reacting an isocyanate compound (A) with an epoxide compound (B) in the presence of a catalyst (C), wherein the isocyanate compound (A) comprises a isocyanate compound (A 1 ) wherein the a isocyanate compound (A1) comprising at least two isocyanate groups (I 1 ≥2), preferred two isocyanate groups (I 1 =2), wherein the epoxide compound (B) comprises a epoxide compound (B 1 ) and an epoxide compound (B 2 ), wherein the epoxide compound (B 2 ) is different from the epoxide compound (B 1 ) wherein the epoxide compound (B 1 ) comprising at least two terminal epoxide groups (F1≥2), preferred two terminal epoxide groups (F 1 =2), linked together by a linking group (L1) and the epoxide compound (B 2 ) comprising at least two terminal epoxide groups (F 2 ≥2)), preferred two terminal epoxide groups (F 2 =2), linked together by a linking group (L 2 ), wherein the linking group (L 2 ) comprises acyclic and covalent bonds to each other free of conjugated multiple bonds within the main chain, wherein the epoxide compound (B 2 ) is present in the epoxide compounds B 1 and B 2 , in an amount of ≥0.01 mol-% to <10 mol-%, preferred 1-9 mol-% more preferred 3-8 mol-% based on the molar ratio the terminal epoxide groups in the epoxide compound (B 1 ) and of the sum of the terminal epoxide groups in the epoxide compound (B 1 ) and terminal epoxide groups in the epoxide compound (B 2 ).

专利号:US-11905228-B2
优先权日:2017-07-11
标 题 :Salts of diaminoacetals and diaminoketals and their synthesis, and their transformations to diaminoacetals and diaminoketals
发明人：KOSINSKI SZYMON; PASTINE STEFAN J; BHATT ULHAS
权利人:ADITYA BIRLA CHEMICALS USA INC
摘要:This application relates, in part, to novel salts represented by the following structure of Formula (1): n n n n n n n n n n wherein R 1a is selected from the group consisting of hydrogen and optionally substituted alkyl (e.g., unsubstituted C 1-6 alkyl, e.g., —CH 3 ); R 1b is optionally substituted alkyl (e.g., unsubstituted C 1-6 alkyl, e.g., —CH 3 ); each occurrence of R 2 and R 3 is independently selected from the group consisting of hydrogen, optionally substituted alkyl, optionally substituted cycloalkyl, and optionally substituted aryl; R 2 and R 3 can combine with each other to form optionally substituted cycloalkyl; each m and n is independently an integer ranging from 1 to 20 (e.g., m and n is independently an integer ranging from 1 to 5); and each of Q 1⊖ and Q 2⊖ is independently a counterion (e.g., each of Q 1⊖ and Q 2⊖ is independently a counterion selected from the group consisting of chloride, bromide, fluoride, iodide, acetate, carboxylate, hydrogen sulfate, nitrate, and phenolate, and sulfonate, e.g., chloride), and methods of making the same.

专利号:US-3953604-A
优先权日:1972-01-14
标 题:1-(2-Substituted-chromonyloxy)-2-hydroxy-3-(substituted phenoxy)propanes
发明人：WARREN BRIAN THOMAS; SPICER JOHN WILLIAM
权利人:MILES LAB
摘要:Definitions: in the following Formulae I, II and IV, R 1 represents hydrogen, alkyl of 1 to 4 carbon atoms, or a nontoxic cation, while each of R 2 , R 3 , R 4 , R 5 , and R 6 symbolizes hydrogen, alkyl of 1 to 4 carbon atoms, alkoxy of 1 to 4 carbon atoms, carboxy, carbalkoxy of 1 to 4 carbon atoms, trihalomethyl, halogen, nitro or cyano. n Certain 1-(2-substituted-chromon-yloxy)-2-hydroxy-3-(substituted-phenoxy)propanes (Formula I), ##SPC1## n can be synthesized from intermediate bis-(substituted-phenoxy)propanes (Formula II), ##SPC2## n by condensation with diethyl oxalate in the presence of sodium ethoxide followed by cyclization with a mixture of glacial acetic acid and concentrated sulfuric or a mixture of concentrated hydrochloric acid and a lower alcohol containing up to 4 carbon atoms. n The bis-(substituted-phenoxy)propane intermediates (Formula II) are prepared by reacting a dihydroxyacetophenone (Formula III), ##SPC3## n with a (substituted-phenyl)glycidyl ether (Formula IV), ##SPC4## n in an organic solvent in the presence of a catalyst. n The 1-(2-substituted-chromon-yloxy)-2-hydroxy-3-(substituted-phenoxy)propanes (Formula I) are useful in the treatment of allergic conditions in mammals. The bis-(substituted-phenoxy)propanes (Formula II) are useful as intermediates in the synthesis of the latter compounds. Methods of preparing compounds having Formulae I and II are described. Methods of treating allergic conditions in mammals utilizing compounds of Formula I are also disclosed.

专利号:EP-3143060-B1
优先权日:2014-05-12
标题 :Catalysts for the synthesis of oxazolidinone compounds