专利号:EP-3748009-A1 优先权日:2019-06-07 标 题 :Synthesis of (r)-pantolactone acetate 发明人:BEKERLE-BOGNER MYRIA; MEDLOCK JONATHAN ALAN; STEINKELLNER GEORG; STROHMEIER GERNOT; STEINER KERSTIN 权利人:DSM IP ASSETS BV 摘要:The present invention relates to a 2-step process comprising step (1) kinetic resolution of R/S-pantolactone using an enantioselective acetylating enzyme and step (2) racemization of (S)-pantolactone in the presence of at least one specific chemical catalyst leading to highly enriched (R)-pantolactone acetate. Both step (1) and (2) might be carried-out in a one-pot reaction/system.
专利号:US-3983177-A 优先权日:1971-06-24 标 题 :Process for the preparation of unsaturated ketones 发明人:GRARD CHARLES 权利人:RHONE POULENC SA 摘要:Ketones, which are intermediates in the synthesis of vitamin A or perfumes, and have the general formula: R2R3 ¦¦ CCH2CR6O (I) ANGLE ANGLE ANGLE ¦ PARALLEL R1--CH2CHCHC-CH2-C-C-R8 n¦¦¦ R4R5R7 wherein R1 is hydrogen or C1-10 hydrocarbon, R2 and R3 are hydrogen or C1-4 alkyl, R4 and R5 are hydrogen or together form a -CH2-CH2-C(CH3)2- group, R6 and R7 are hydrogen or C1-10 hydrocarbon, or together with the carbon atom to which they are joined form a hydrocarbon ring of up to 10 carbons, or ¦ R6-C-C-R8 ¦ PARALLEL R7O forms a hydrocarbon ring of up to 10 carbons joined through R6 and R8 or R7 and R8, R8 is hydrogen or C1-10 hydrocarbon and n is 0-6, are prepared by reacting an unsaturated halide of formula R2R3 ¦¦ CCH2CCH2X (II) ANGLE ANGLE ANGLE ¦ R1--CH2CHCHC n¦¦ R4R5 wherein X is halogen, with an enol ester of formula R6 ANGLE C=C-R8 (III) ¦ R7OOC-R9 wherein R9 is C1-20 hydrocarbon, in the presence of a metal catalyst.
专利号:US-7696349-B2 优先权日:2003-11-25 标 题 :Method for asymmetric synthesis 发明人:JAEKEL CHRISTOPH; VOLLAND MARTIN; MACKEWITZ THOMAS; PACIELLO ROCCO; BREIT BERNHARD; SEICHE WOLFGANG; WEIS MARTINE; WALOCH CHRISTOPH 权利人:BASF SE 摘要:The present invention relates to a process for asymmetric synthesis in the presence of a chiral catalyst comprising at least one complex of a metal of transition group VIII with ligands capable of dimerization via noncovalent bonds, such catalysts and their use.
专利号:US-2025034074-A1 优先权日:2021-11-25 标题:Process for preparing a cyclic diene 发明人:JACOBY DENIS; CHAPPUIS SIMONE; KELLER FABRICE 权利人:FIRMENICH & CIE 摘要:The present invention relates to the field of organic synthesis and more specifically it concerns a process for preparing compound of formula (I) comprising the reaction of a compound of the formula (II) with a base having a boiling point superior to the boiling point of the compound of formula (I). Moreover, the compound of formula (I) and the compound of formula (II) are also part of the invention.
专利号:US-2024327367-A1 优先权日:2021-07-30 标 题 :Process for preparing a oxacylohexane or oxacylopentane derivative 发明人:DAPSENS PIERRE-YVES; VILCOQ LEA 权利人:FIRMENICH & CIE 摘要:The present invention relates to the field of organic synthesis and, more specifically, it concerns a process for the preparation of a cycloether of formula (I) comprising the cyclisation of compound of formula (II) performed in the presence of heterogenous acidic catalyst.
专利号:US-2009227801-A1 优先权日:2004-10-26 标 题 :Ligands for use in asymmetric hydroformylation 发明人:AHLERS WOLFGANG; EGEN MARTINA; VOLLAND MARTIN; JAKEL CHRISTOPH; HETTCHE FRANK; PACIELLO ROCCO 权利人:BASF AG 摘要:The invention relates to chiral phosphorus chelate compounds, to catalysts comprising such a compound such a compound as the ligand, and to asymmetric synthesis methods in the presence of such a catalyst.