CAS: 15753-50-1; Cis-Cyclohexane-1,2-Diyldimethanol

该化合物是一种手性二醇,其特征是环氧乙烷脊椎,其相对配置为两个氢氧基组(1R,2S),这种立体化学具有独特的反应性和选择性,使其作为不对称合成和手电筒设计的一个构件具有价值,其硬性环乙烷结构增强了热和化学稳定性,而氢氧基组则提供了衍生的功能处理器.该化合物在准备需要精确立体控制的光活性聚合物,药品和专门材料方面特别有用.其高纯度和定义明确的配置确保了先进应用的再生性.该产品通常作为具有一贯的批次质量的白晶状固体供应.

英文名称Cis-Cyclohexane-1,2-Diyldimethanol
中文名称顺-1,2-环己基二甲醇
IUPAC名称((1R,2S)-cyclohexane-1,2-diyl)dimethanol
其它别名1,2-Cyclohexanedimethanol,cis- (8CI); (1R,2S)-rel-1,2-Cyclohexanedimethanol; (cis-2-Hydroxymethylcyclohexyl)methanol; 1,2-cis-Cyclohexanedimethanol; cis-1,2-Bis(hydroxymethyl)cyclohexane; cis-1,2-Cyclohexanedimethanol; cis-[2-(Hydroxymethyl)cyclohexane]methanol
CAS编号15753-50-1
MFCD编号:MFCD00062987
EINECS号:239-843-6
FDA UNII编号:ALJ6CW3JCQ
分子式:C8H16O2
分子量:144.21
产品CID: 787092
产品分类Chemistry → Organic Building Blocks → Aliphatic Cyclic Hydrocarbons | Alcohols

相似结构搜索
产品信息参考;;;;
InChIKey: XDODWINGEHBYRT-UHFFFAOYNA-N
InChI=1S/C8H16O2/c9-5-7-3-1-2-4-8(7)6-10/h7-10H,1-6H2/t7-,8+…
计算化学: 氢键受体数2.0氢键供体数2.0可旋转键数2.0

物理性质

熔点43-45 °C(文献)
沸点270.1±8.0 °C at 760 mmHg
闪点129.0±13.0 °C
密度1.0±0.1 g/cm3
pKa:14.75±0.10(预测)
PSA:40.46
LogP:0.53
折射率1.471
蒸汽压0.0±1.2 mmHg at 25°C
溶解性Chloroform (Slightly, Sonicated), Methanol (Slightly)
敏感性按规定使用不会分解，避氧化剂
外观形态白色至类白色固体
储存条件密封, 常温干燥保存
产品应用该化合物用于合成9-{[(Z)-2(氢氧甲基)环己基]甲酸甲酯.

MSDS等安全信息

危险类别急性毒性类别4(经口)
特定目标器官毒性 - 单次接触类别3
皮肤腐蚀/刺激类别2
严重眼刺激类别2A
警示词Warning
危险描述H302 |吞咽有害.
H335 |可能引起呼吸道刺激.
H315 |造成皮肤刺激.
H319 |造成严重眼刺激.
防范说明P280-P305+P351+P338-
UN编号NONH for all modes of transport
危险品标志Xn
安全声明24/25
WGK Germany3

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

合成工艺路线路线简述

海关参考信息

2905121000-正丙醇
2905399002-1,4-丁二醇
2905141000-异丁醇
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

专利信息

专利号:WO-2012002913-A1
优先权日:2010-07-02
标题:Process of forming a cyclic imide
发明人：HONG SOON HYEOK; ZHANG JIAN; MUTHAIAH SENTHILKUMAR; GHOSH SUBHASH CHANDRA
权利人:UNIV NANYANG TECH; HONG SOON HYEOK; ZHANG JIAN; MUTHAIAH SENTHILKUMAR; GHOSH SUBHASH CHANDRA
摘要:A process is provided for the synthesis of a cyclic imide. A primary amine and a diol compound are contacted in the presence of a Ruthenium (II) complex. The Ruthenium (II) catalyst includes at least one of an alicyclic ligand, an aromatic ligand, an arylalicyclic ligand, an arylaliphatic ligand and a phosphine ligand.

专利号:WO-9855085-A1
优先权日:1997-06-04
标题:Pharmaceutical compositions and methods
发明人：BROWN DAVID A; KHORLIN ALEXANDER A; LESIAK KRYSTYNA; REN WU YUN
权利人:CODON PHARMACEUTICALS INC; BROWN DAVID A; KHORLIN ALEXANDER A; LESIAK KRYSTYNA; REN WU YUN
摘要:Disclosed are methods and compositions for regulating the melanin content of mammalian melanocytes; regulating pigmentation in mammalian skin, hair, wool or fur; treating or preventing various skin and proliferative disorders; increasing the differentiation of mammalian neuronal cells for purposes of treating neurodegenerative diseases or nerve damage; and stimulating cellular nitric oxide (NO) synthesis, cyclic guanosine monophosphate levels (cGMP), and protein kinase G (PKG) activity for purposes of treating diseases mediated by deficiencies in the NO/cGMP/PKG signal transduction pathway; by administration of various compounds, including alcohols, diols and/or triols and their analogues.

专利号:RU-2126794-C1
优先权日:1992-03-11
标题 :Amino-derivatives of oxo- or hydroxy-substituted hydrazines, method of their synthesis and pharmaceutical compositions for inhibition of retrovirus protease