CAS: 15501-33-4; Neopentyl Iodide

上下游产品

2,2-dimethyl-propanol-1 neopentyl tosylate 2,2-dimethylpropylmagnesium chloride methyl iodide2,2-dimethylpropane 1-ethoxy-2,2-dimethyl-propane 2-methyl-2-butylchloride 2,3-dichloro-2-methylbutane

📜新戊烷置于次氯酸叔丁酯,Mercury(II) Iodide体系中,用 1,1,2-三氯三氟乙烷(cfc-113) 用作溶剂,化学反应 8.0H,以28%的收率获得新戊基碘
参考文献:关于叔丁基次碘酸盐的结构
标题:关于叔丁基次碘酸盐的结构
摘要:在donne Trois Methodes De制备de Ce 组成:反应de L'次氯酸盐de T-Butyle Avec L'Iode,Reaction De L'次氯酸盐de L'次氯酸盐de T-Butyle Avec Les Iodures Metalliques和reaction Du T-Butylate De K Avec L'Iode Reactive De L'Hypoiodite De T-Butyle
Doi:10.1021/ja00330A038

专利信息

专利号:US-3647837-A
优先权日:1970-02-09
标 题 :Synthesis of organolead compounds
发明人：WILLIAMS KENNETH C
权利人:ETHYL CORP
摘要:A METHOD OF MAKING ORGANOLEAD COMPOUNDS AND PARTICULARLY THE SYNTHESIS OF TETRANEOPENTYLLEAD AND HEXANEOPENTYLDILEAD FROM AN INORGANIC LEAD (II) SALT, AND THE USE OF SAID LEAD COMPOUNDS FOR DECREASING KNOCK IN INTERNAL COMBUSTION ENGINES.

专利号:US-2023357286-A1
优先权日:2020-07-24
标 题:Ketone synthesis and applications
发明人：KISHI YOSHITO; UMEHARA ATSUSHI
权利人:HARVARD COLLEGE
摘要:Provided are new nickel./zirconium-mediated coupling reactions useful in the synthesis of ketone-containing compounds, e.g., halichondrin natural products and related molecules. A feature of the present disclosure is the use of a nickel(I) catalyst in tandem with a nickel (II) catalyst in the Ni/Zr-mediated coupling reactions. Without wishing to be bound by any particular theory, the nickel (I) catalyst selectively activates the electrophilic coupling partner (i.e., the compound of Formula (A)), and the nickel(ll) catalyst selectively activates the nucleophilic coupling partner (i.e., a thioester of Formula (B)). This dual catalyst system leads to improved coupling efficiency and eliminates the need for a large excess of one of the coupling partners (i.e., a compound of Formula (A) or (B)).

专利号:US-9346851-B2
优先权日:2008-02-22
标 题 :Chemical modification of proteins
发明人：BERNARDES GONCALO; CHALKER JUSTIN; DAVIS BENJAMIN
权利人:BERNARDES GONCALO; CHALKER JUSTIN; DAVIS BENJAMIN; RP SCHERER TECHNOLOGIES LLC
摘要:The invention relates to methods for selectively converting a cysteine residue in a peptide or protein to the dehydroalanine (Dha) residue. The method also works on selenocysteine and substituted cysteine and selenocysteine residues, resulting in the Dha residue which may be converted to any natural or unnatural amino acid residue desired without the alteration of the remainder of the peptide or protein. The invention also allows ligation of a desired peptide at any point rather than at a point where there should be a naturally occurring cysteine, thereby allowing native chemical ligation to be used in the synthesis of peptides that do not contain cysteine. The methodology allows for the synthesis of very large peptides.

专利号:US-4593147-A
优先权日:1984-11-01
标 题:Synthesis of neoalkanes
发明人：BUTTER STEPHEN A; STOLL ILSE
权利人:AIR PROD & CHEM
摘要:Neoalkanes of the formula R1R2R3CCH3 are synthesized by hydrogenation of a neoacid of the formula R1R2R3CCOOH or a neoalcohol of the formula R1R2R3CCH2OH, wherein R1, R2 and R3 are the same or different alkyl of 1-10 carbon atoms, at a temperature of 250 DEG -500 DEG C. over a copper oxide/zinc oxide catalyst.

专利号:US-2005192265-A1
优先权日:2003-03-20
标 题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
发明人：THOMPSON RICHARD C; WILKIE STEPHEN; STACK DOUGLAS R; VANMETER ELDON E; SHI QING; BRITTON THOMAS C; AUDIA JAMES E; REEL JON K; MABRY THOMAS E; DRESSMAN BRUCE A; CWI CYNTHIA L; HENRY STEVEN S; MCDANIEL STACEY L; STUCKY RUSSELL D; PORTER WARREN J
摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions that include a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

专利号:WO-9967219-A1
优先权日:1998-06-22
标 题:Compounds for inhibiting beta-amyloid peptide release and/or its synthesis
发明人：AUDIA JAMES E; PORTER WARREN J; THOMPSON RICHARD C; WILKIE STEPHEN C; STACK DOUGLAS R; SHI QING
权利人:ELAN PHARM INC; LILLY CO ELI; AUDIA JAMES E; PORTER WARREN J; THOMPSON RICHARD C; WILKIE STEPHEN C; STACK DOUGLAS R; SHI QING
摘要:Compounds of formula (I), wherein W is a cyclic group of the type (2); (3); Y is represented by the formula (II); these compounds inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.