CAS: 15110-17-5; Diethyl (3,3-Diethoxypropyl)Phosphonate

该化合物是有机磷化合物,其特点是磷的功能组群,该物质一般是无色的,淡黄色液体,以相对低的挥发性而著称;其特点是磷酸盐,它有助于其反应和在各种化学工艺中的潜在应用,包括作为有机合成的试剂; 乙氧基组的存在提高了其在有机溶剂中的溶解性,使其在配方和化学反应中有用; 此外,二乙基(3,3-三-二氧丙基丙基)磷可展示生物活动,这需要谨慎处理潜在的毒性;其化学结构允许水解的可能性,导致二乙基磷酸和其他副产品在某些条件下释放;与许多有机磷化合物一样,在实验室或工业环境中与该物质合作时,必须考虑安全数据和管制准则.

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3699-67-0 2327-69-7 7203-67-0

上下游产品

3-chloro-1,1-diethoxy-propane sodium diethyl phosphite triethyl phosphite 3-bromopropinaldehyde diethyl acetaldiethyl (3-oxopropyl)phosphonate (3-Benzylamino-3-cyano-1-methyl-propyl)-phosphonic acid diethyl ester diethyl 3-(N-(benzyloxy)-2-phenylacetamido)propylphosphonate diethyl 3-(N-(benzyloxy)-4-phenylbutanamido)propylphosphonate

合成工艺路线路线简述

    📜3-氯丙醛二乙醇缩醛,Sodium Diethyl Phosphite 以 N,N-二甲基甲酰胺 用作溶剂,化学反应生成(3,3-二乙氧基丙基)磷酸二乙酯
    参考文献:Normant,H.; Sturtz,G.,Comptes Rendus Hebdomadaires Des Seances De L'Academie Des Sciences,1961,Vol. 253,P. 2366-2368
    标题:Normant,H.; Sturtz,G.,Comptes Rendus Hebdomadaires Des Seances De L'Academie Des Sciences,1961,Vol. 253,P. 2366-2368

    海关参考信息

    专利信息


    专利号:US-4145510-A
    优先权日:1976-06-21
    标 题:5-Substituted phosphonate hydantoins and derivatives thereof
    发明人:HALL LUTHER A R; GORDON DAVID A
    权利人:CIBA GEIGY CORP
    摘要:Hydantoins of the formula wherein R1 is hydrogen or alkyl of 1 to 8 carbon atoms, R2 is R3 is alkyl of 1 to 8 carbon atoms, and X is a straight or branched chain alkylene of 1 to 4 carbon atoms or a straight or branched chain alkylene of 3 to 6 carbon atoms containing an internal carbamido group; or R1 and R2 together are Y where Y is a straight or branched chain alkylene of 4 to 8 carbon atoms having a pendant ARE PREPARED BY REACTING FIRST alpha , beta -UNSATURATED ALDEHYDES OR KETONES WITH ALKYL PHOSPHITES TO FORM A PHOSPHONATE ALDEHYDE OR KETONE FOLLOWED BY A CLASSICAL Bucherer hydantoin synthesis.

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    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1021/jm00177a018
    摘要:Cates LA, Jones GS, Good DJ, Tsai HY, Li VS, Caron N, Tu SC, Kimball AP. Cyclophosphamide potentiation and aldehyde oxidase inhibition by phosphorylated aldehydes and acetals. J Med Chem. 1980 Mar;23(3):300–4. doi: 10.1021/jm00177a018.
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