CAS: 15074-54-1; 2-Chlorophenyl Phosphorodichloridate

该化合物是一种反应性有机磷磷化合物,主要用作有机合成中的磷酸剂,其主要优点包括对核分裂物具有高度的反应性,使其对磷酸酯和其他衍生物的准备工作具有价值;2氯苯基组的存在增强了其稳定性,同时在受控制的条件下保持了高效的反活动;该化合物在合成农用化学品,药品和阻燃剂方面特别有用;由于对湿度的敏感性,通常在惰性条件下处理;适当储存和处理对于保持其完整性和确保合成应用的一贯性至关重要.

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CAS号95-57-8 邻氯苯酚 | CAS号35535-81-0 Sodium 2-chloro... | CAS号95-57-8 邻氯苯酚 | CAS号95-50-1 邻二氯苯 | CAS号115-85-5 Phosphoric acid... | CAS号72351-28-1 1-[(2-chlorophe...

合成工艺路线路线简述

    📜邻氯苯酚置于calcium Chloride,三氯氧磷体系中,化学反应生成2-氯苯基二氯膦
    参考文献:Zenftman,1958,Vol. 18,P. 361,363
    标题:Zenftman,1958,Vol. 18,P. 361,363

    海关参考信息

    专利信息


    专利号:US-5359016-A
    优先权日:1993-03-29
    标 题 :Process for the synthesis of styrene-isoprene rubber
    发明人:HSU WEN-LIANG; HALASA ADEL F; MATRANA BARRY A
    权利人:GOODYEAR TIRE & RUBBER
    摘要:The subject invention relates to a technique for synthesizing rubbery copolymers of styrene and isoprene. These rubbery copolymers exhibit an excellent combination of properties for utilization in tire tread rubber compounds. By utilizing these styrene-isoprene rubbers in tire treads, tires having improved wet skid resistance can be built without sacrificing rolling resistance or tread wear characteristics. This invention more specifically discloses a process for the synthesis of styrene-isoprene rubbers which comprises copolymerizing isoprene monomer and styrene monomer in an organic solvent in the presence of a catalyst system which is comprised of (a) a lithium initiator and (b) an alkyl tetrahydrofurfuryl ether modifier, wherein the molar ratio of the modifier to the lithitium initiator is within the range of 2:1 to 40:1. The subject invention further discloses a process for the synthesis of styrene-isoprene rubbers which comprises copolymerizing isoprene monomer and styrene monomer in an organic solvent in the presence of a catalyst system which is comprised of (a) a lithium initiator and (b) 2,2-ditetrahydrofurylpropane as a modifier, wherein the molar ratio of the modifier to the lithium initiator is within the range of 1:1 to 40:1.

    专利号:US-7777023-B2
    优先权日:1998-10-23
    标题 :Method for the chemical synthesis of oligonucleotides
    发明人:VARGEESE CHANDRA; SHAFFER CHRISTOPHER; WANG WEIMIN
    权利人:SIRNA THERAPEUTICS INC
    摘要:The present invention features novel compositions, linkers, derivatized solid supports, and methods for the efficient solid phase synthesis of oligonucleotides, including RNA, DNA, RNA-DNA chimeras, and analogs thereof.

    专利号:US-3891594-A
    优先权日:1972-04-07
    标题:Direct synthesis of composite materials
    发明人:TAYLOR LYNN J
    权利人:TAYLOR LYNN J
    摘要:There is disclosed an in situ process for the preparation of a composite material consisting essentially of an organic polymer or copolymer having dispersed therein an inorganic oxide or mixture of oxides, said process comprising the simultaneous or sequential synthesis of the organic polymer from at least one non-polymeric organic precursor and of the inorganic oxide or oxide mixture derived from at least one inorganic-oxide precursor.

    专利号:US-3817911-A
    优先权日:1972-04-07
    标 题 :Direct synthesis of composite materials
    发明人:TAYLOR L
    权利人:TAYLOR L
    摘要:THERE IS DISCLOSED AN IN SITU PROCESS FOR THE PREPARATION OF A COMPOSITE MATERIAL CONSISTING ESSENTIALLY OF AN ORGANIC POLYMER OR COPOLYMER HAVING DISPERSED THEREI AN INORGANIC OXIDE OR MIXTURE OF OXIDES, SAID PROCESS COMPRISING THE SIMULTANEOUS OR SEQUENTIAL SYNTHESIS OF THE ORGANIC POLYMER FROM AT LEAST ONE NON-POLYMERIC ORGANIC PRECUROR AND OF THE INORGANIC OXIDE OR OXIDE MIXTURE DERIVED FROM AT LEAST ONE INORGANIC-OXIDE PRECURSOR.

    专利号:US-3960805-A
    优先权日:1974-04-19
    标 题:Direct synthesis of organic polymer-inorganic oxide composites
    发明人:TAYLOR LYNN JOHNSTON
    权利人:TAYLOR LYNN JOHNSTON
    摘要:There is disclosed an in situ process for the preparation of a composite material consisting essentially of an organic polymer or copolymer having dispersed therein an inorganic oxide or mixture of oxides, said process comprising the simultaneous or sequential synthesis of the organic polymer from at least one non-polymeric organic precursor and of the inorganic oxide or oxide mixture derived from at least one inorganic-oxide precursor.

    专利号:US-5336739-A
    优先权日:1992-04-06
    标题:Alkyl tetrahydrofurfuryl ethers as anionic polymerization modifier in the synthesis of rubbery polymer
    发明人:HSU WEN-LIANG; HALASA ADEL F; MATRANA BARRY A
    权利人:GOODYEAR TIRE & RUBBER
    摘要:It has been unexpectedly discovered that various compounds, such as alkyl tetrahydrofurfuryl ethers, can be used to modify anionic polymerizations of conjugated diene monomers. These modifiers can be used to polymerize isoprene monomer into high 3,4-polyisoprene at excellent polymerization rates. This is in contrast to the modifiers such as tetramethylethylene diamine which are typically used to modify such polymerizations. This invention more specifically discloses a process for the synthesis of 3,4-polyisoprene which comprises polymerizing isoprene monomer in an organic solvent in the presence of a catalyst system which is comprised of (a) a lithium initiator and (b) a modifier which is an alkyltetrahydrofurfuryl ether selected from the group consisting of ethyltetrahydrofurfuryl ether, propyltetrahydrofurfuryl ether, and butyltetrahydrofurfuryl ether. In the practice of this invention, the utilization of ethyltetrahydrofurfuryl ether is highly preferred since its use results in faster polymerization rates and higher vinyl contents in the resultant polymer.

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    合成参考文献


    参考文献:10.1007/978-981-19-9776-1_20
    摘要:Saito-Tarashima N, Minakawa N. Chemistry of Cyclic Dinucleotides and Analogs. 2023. In: Handbook of Chemical Biology of Nucleic Acids.
    参考文献:10.1134/s1068162023080010
    摘要:Makarov DA, Oskolsky IA, Jasko MV, Solyev PN, Vasilyeva BF, Demiankova MV, Efremenkova OV, Kochetkov SN, Alexandrova LA. 5-Alkyloxymethyl Derivatives of 2ʹ-Deoxyuridine Bearing 2,4-Dinitrophenyl and Dansyl Groups: Synthesis and Antibacterial Activity. Russ J Bioorg Chem. 2023 Dec;49(S1):S1–7. doi: 10.1134/s1068162023080010.
    参考文献:10.1134/s1068162025602332
    摘要:Makarov DA, Jasko MV, Karpenko IL, Urbina EV, Popenko VI, Leonova OG, Tkachev YV, Vasilyeva BF, Efremenkova OV, Kochetkov SN, Alexandrova LA. Synthesis and Antibacterial Activity of Ethynyl and Azido Derivatives of N4-Dodecylamino-2′-deoxycytidine. Russ J Bioorg Chem. 2025 Dec;51(6):2710–8. doi: 10.1134/s1068162025602332.
    参考文献:10.1134/s1068162025602411
    摘要:Makarov DA, Jasko MV, Karpenko IL, Tkachev YV, Vasilyeva BF, Efremenkova OV, Kochetkov SN, Alexandrova LA. N4-(ω-Aminoalkyl)- and N4-(ω-Dansylaminoalkyl)-5-methyl-2′-deoxycytidines. Russ J Bioorg Chem. 2025 Dec;51(6):2719–24. doi: 10.1134/s1068162025602411.
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