CAS: 146724-94-9; (Z)-3,3-Bis(2-Aminoethyl)-1-Hydroxytriaz-1-Ene 2-Oxide

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CAS号111-40-0 二乙烯三胺

📜二乙烯三胺置于氧化亚氮,Sodium Methylate体系中,用 甲醇 用作溶剂,化学反应 72.0H,反应生成3,3-二(氨乙基)-1-羟基-2-羰基-1-三氮烯,双(2-氨基乙基)-N-亚硝胺
参考文献:Competitive Formation Of N-Diazeniumdiolates And N-Nitrosamines Via Anaerobic Reactions Of Polyamines With Nitric Oxide
标题:Competitive Formation Of N-Diazeniumdiolates And N-Nitrosamines Via Anaerobic Reactions Of Polyamines With Nitric Oxide
摘要:Reactions Of Amines With Nitric Oxide (No) At High Pressures Form Diverse No Donor Species,Highly Dependent On The Precursor Structure. While Monoamine Precursors Favor The Formation Of N-Diazeniumdiolates In High Yield,Polyamines Exhibit Competitive Formation Of N-Nitrosamines And Diazeniumdiolates,Resulting In Mixed Products Containing Significant Percentages Of Undesired N-Nitroso Compounds.
Doi:10.1021/ol902282Y

专利信息

专利号:WO-2024172286-A1
优先权日:2023-02-14
标题 :Synthesis of photodegradable iron nitrosyl complex and development of pharmaceutical composition for prevention or treatment of vascular diseases, using same
发明人：CHO JAEHEUNG; LEE JUNYEOP; CHOE JISU
权利人:ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECH; ASAN FOUND; UNIV ULSAN FOUND IND COOP
摘要:The present invention relates to a compound represented by chemical formula 1 or a pharmaceutically acceptable salt thereof, a compound represented by chemical Formula 2 or a pharmaceutically acceptable salt thereof, a preparation method thereof, and uses of the compound represented by chemical formula 2 or a pharmaceutically acceptable salt thereof. The compound represented by chemical formula 2 or a pharmaceutically acceptable salt thereof exhibits the effect of releasing nitric oxide in vivo upon light stimulation, thereby dilating blood vessels.