CAS: 13067-19-1; N-(Benzo[d][1,3]Dioxol-5-yl)Acetamide

上下游产品

3,4-亚甲二氧基苯胺 Benzo[1,3]Dioxolo-5-Ylamine 14268-66-7
1,2-亚甲基双氧-4-硝基苯 5-Nitro-1,3-Benzodioxole 2620-44-2

📜胡椒环乙酮肟置于ca(Bis(Triflimide))2,Tert-Butylammonium Hexafluorophosphate(V)体系中,用 乙二醇二甲醚,1,2-二氯乙烷 用作溶剂,以78%的收率获得3,4-亚甲基二氧基乙酰苯胺
参考文献:轻度钙催化贝克曼重排
标题:轻度钙催化贝克曼重排
摘要:已经实现了轻度钙催化的贝克曼重排,这消除了与转化相关的更传统的苛刻反应条件.已表明该催化剂体系对与天然产物合成和药物化学有关的多种官能团具有耐受性,并且还研究了该反应的合成效用.进行了初步的机械研究,以了解传入亲核试剂的性质,并描述了可能的反应途径.
Doi:10.1039/c7Cc09491D

专利信息

专利号:US-2003180804-A1
优先权日:2001-10-29
标题:Solid phase synthesis of chemical libraries
发明人：PRYOR KENT E; LEWIS RONALD D; BROWN JASON W
权利人:CORVAS INT INC
摘要:The present invention provides compounds and compound libraries that are useful as protease modulators. The compounds and compound libraries are preferably made using the methods of the present invention which utilize peptide synthesis and combinatorial chemistry methods on a solid phase.

专利号:US-5342947-A
优先权日:1992-10-09
标 题:Preparation of water soluble camptothecin derivatives
发明人：LACKEY Karen; STERNBACH DANIEL D
权利人:GLAXO INC
摘要:The present invention relates to the synthesis of water soluble, camptothecin derivatives of formula (I), (I) wherein: n represents the integer 1 or 2; R1 represents independently, hydrogen, lower alkyl, (C3-7)cycloalkyl, (C3-7)cycloalkyl lower alkyl, lower alkenyl, hydroxy lower alkyl, lower alkoxy lower alkyl; and R2 represents hydrogen and the pharmaceutically acceptable salts thereof.