CAS: 120912-37-0; 5-Isocyanato-2,3-Dihydro-1H-Indene

上下游产品

bis(trichloromethyl) carbonate indan-5-amine 4-[1-(2-dimethylaminoethyl)-3-(indan-5-yl)ureidomethyl] benzoic acid benzyl ester 4-{[(2,3-dihydro-1H-inden-5-yl)amin°Carbonyl]amino}benzenesulfonamide 1-(benzyloxy)-3-(2,3-dihydro-1H-inden-5-yl)urea 1-(benzyloxy)-3,5,6,7-tetrahydroindeno[5,6-d]imidazol-2(1H)-one

📜5-氨基茚旦 反应生成5-茚满基异氰酯酯
参考文献:Wang,Chia-Lin J.;Wuonola,Mark A.
标题:Wang,Chia-Lin J.;Wuonola,Mark A.

专利信息

专利号:US-8076332-B2
优先权日:2006-12-26
标 题:N- (2-aminophenyl) benzamide derivative having urea structure
发明人：MOGI HIROYUKI; TAJIMA HISASHI; MISHINA NORIKO; YAMAZAKI YUSUKE; YONEDA SHINJI; WATANABE KATSUHIKO; FUJIKAWA JUNKO; YAMAMOTO MINORU
权利人:MOGI HIROYUKI; TAJIMA HISASHI; MISHINA NORIKO; YAMAZAKI YUSUKE; YONEDA SHINJI; WATANABE KATSUHIKO; FUJIKAWA JUNKO; YAMAMOTO MINORU; SANTEN PHARMACEUTICAL CO LTD
摘要:The present invention relates to a study on the synthesis of a novel N-(2-aminophenyl)benzamide derivative having an urea structure and represented by the general formula (1); and the utilization of a pharmacological effect of the derivative. A compound represented by the general formula (1) or a salt thereof has an effect of cellular morphological change on trabecular meshwork cells and is effective in the prevention and/or treatment of a disease considered to be related to intraocular pressure. In the formula, R 1 and R 2 represent a hydrogen atom, a lower alkyl group, or the like; R 3 represents a hydroxy group, a lower alkoxy group, a lower cycloalkyloxy group, an aryloxy group, or the like; R 4 and R 5 represent a halogen atom, a lower alkyl group, a hydroxy group, a lower alkoxy group, or the like; X represents a lower alkylene group or the like; Y represents a single bond, a lower alkylene group, or the like; l and m represent 0, 1, 2, or the like.

专利号:US-9833457-B2
优先权日:2008-01-25
标题:Tricyclic compounds as modulators of TNF-α synthesis and as PDE4 inhibitors
发明人：MJALLI ADNAN M M; GADDAM BAPU; POLISETTI DHARMA RAO; KOSTURA MATTHEW J; GUZEL MUSTAFA
权利人:VTV THERAPEUTICS LLC
摘要:The present invention relates to chemical compounds of Formula (I) are as herein defined, pharmaceutical compositions, and methods of use in the treatment of conditions or disorders mediated by TNF-α or by PDE4, including but not limited to psoriatic arthritis.

专利号:US-10822377-B2
优先权日:2015-03-04
标 题:Substituted urea depsipeptide analogs as activators of the ClpP endopeptidase
发明人：LEE RICHARD E; ZHAO YING; JIUYU LIU
权利人:ST JUDE CHILDRENS RES HOSPITAL
摘要:In one aspect, the invention relates to substituted urea depsipeptide analogs, derivatives thereof, and related compounds, which are useful as activators the ClpP endopeptidease; synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating infectious disease using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

专利号:MX-2010007768-A
优先权日:2008-01-25
标题 :TRICICLIC COMPOUNDS AS MODULATORS OF THE SYNTHESIS OF THE ALFA TUMOR NECROSIS FACTOR AND AS INHIBITORS OF PHOSPHODIESTERASE 4.

专利号:WO-2009094528-A1
优先权日:2008-01-25
标 题:TRICYCLIC COMPOUNDS AS MODULATORS OF TNF-α SYNTHESIS AND AS PDE4 INHIBITORS

专利号:US-2012172381-A1
优先权日:2008-01-25
标题 :Tricyclic Compounds as Modulators of TNF-alpha Synthesis and as PDE4 Inhibitors