📜二硫代磷酸二乙酯置于氨体系中,化学反应生成克菌磷 参考文献: Dithiophosphato-Platinum-Complexes For The Treatment Of Cancers[fr] Complexes De Dithiophosphato-Platine Destines Au Traitement De Cancers 标题: Dithiophosphato-Platinum-Complexes For The Treatment Of Cancers[fr] Complexes De Dithiophosphato-Platine Destines Au Traitement De Cancers 摘要:公式组合:(I),(II)或(III):哪一个适合用于肿瘤治疗.
专利信息
专利号:WO-9849181-A1 优先权日:1997-04-30 标题:Novel sulfur transfer reagents for oligonucleotide synthesis 发明人:TANG JIN YAN; ZHANG ZHAODA; NICHOLS ALEXANDRA 权利人:HYBRIDON INC 摘要:The invention relates to the chemical synthesis of oligonucleotides and to chemical entities useful in such synthesis. More particularly, the invention relates to sulfurization of the internucleoside linkages of oligonucleotides. The invention provides new sulfur transfer reagents of formula (1) and processes for their use in sulfurizing oligonucleotides. The sulfur transfer reagents according to the invention are inexpensive to make, stable in storage, and highly efficient in sulfurization. In Formula (1) n = 1 to 4, and wherein R can be the same as or different from R1, and wherein R and R1 are selected from the group consisting of CH¿3?, CH2CH3, tert-butyl, Formula (2), (3), (4), wherein R?2, R3 and R4¿, are selected from the group consisting of Cl, Br, I, CN, NO¿2?, CH3, and CH2CH3, and wherein R?1, R2, R3 and R4¿, taken separately are hydrogen, lower alkyl, electron-withdrawing substituted lower alkyl, lower alkyl- or halo-substituted aryl, or a heterocycle containing nitrogen, oxygen, or sulfur and from 5-8 carbon atoms.
专利号:SU-1735300-A1 优先权日:1990-01-22 标题 :Method for synthesis of s-trimethylsilyl esters of dithio- or tetrathiophosphoric acids