CAS: 76568-02-0; Flosequinan

相似化合物

76561-14-3 591781-26-9 2169907-32-6

上下游产品

CAS号154639-75-5 1-[4-fluoro-2-(... | CAS号77-78-1 硫酸二甲酯 | CAS号76561-14-3 7-fluoro-3-meth... | CAS号122-51-0 原甲酸三乙酯 | CAS号321-50-6 7-氟-2H-3,1-苯并噁嗪... | CAS号2252-51-9 2-氯-4-氟苯甲酸 | CAS号128992-62-1 4-氟-2-(甲基氨基)苯甲酸 | CAS号97927-92-9 7-fluoro-2-meth...

📜1-(4-Fluoro-2-Methylaminophenyl)-2-Methylsulfinylethanone置于sodium Hydroxide,甲酸,乙酸酐体系中,用 水,甲苯 作为反应溶剂,化学反应生成 氟司喹南
参考文献:Process For The Preparation Of 1-Methyl-3-Methylthio-4-Quinolone And The
标题:Process For The Preparation Of 1-Methyl-3-Methylthio-4-Quinolone And The
摘要:一种制备化合物i的过程,其中n=0,1或2,包括将化合物ii环化的步骤,其中n=0,1或2.环化可以在有机或无机碱的存在下或在40-160摄氏度范围内热处理的条件下进行.化合物ii及其某些类似物被披露为心血管药物.

专利信息

专利号:US-10925977-B2
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
发明人：YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S
权利人:YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S; CEIL POINT LLC; UNIV TEXAS
摘要:Novel methods of synthesis of chelator-targeting ligand conjugates, compositions comprising such conjugates, and therapeutic and diagnostic applications of such conjugates are disclosed. The compositions include chelator-targeting ligand conjugates optionally chelated to one or more metal ions. Methods of synthesizing these compositions in high purity are also presented. Also disclosed are methods of imaging, treating and diagnosing disease in a subject using these novel compositions, such as methods of imaging a tumor within a subject and methods of diagnosing myocardial ischemia.

专利号:US-6730790-B2
优先权日:2002-03-01
标 题:Chlorinated heterocyclic compounds and methods of synthesis
发明人：KWIATKOWSKI STEFAN; GOLINSKI MIROSLAW
权利人:R T ALAMO VENTURES I LLC
摘要:Compositions of the present invention comprise chlorinated heterocyclic compounds, including racemic monochloroflosequinan, purified enantiomers of monochloroflosequinan and the sulfone derivative of monochloroflosequinan. The methods of the present invention comprise the synthesis of racemic monochloroflosequinan and derivatives thereof, including the sulfone derivative. Intermediates in the synthesis are also provided. The methods further comprise the synthesis of enantiomers of monochloroflosequinan.

专利号:US-7034040-B2
优先权日:2002-03-01
标题:Fluorinated heterocyclic compounds and methods of synthesis
发明人：KWIATKOWSKI STEFAN; GOLINSKI MIROSLAW
权利人:R T ALAMO VENTURES I
摘要:Compositions of the present invention comprise fluorinated heterocyclic compounds, including monofluoroflosequinan and difluoroflosequinan. The methods of the present invention comprise the synthesis of monofluoroflosequinan and difluoroflosequinan.

专利号:US-7045627-B2
优先权日:2002-03-01
标题:Dichlorinated heterocyclic compounds and methods of synthesis
发明人：KWIATKOWSKI STEFAN; GOLINSKI MIROSLAW
权利人:R T ALAMO VENTURES I LLC
摘要:Compositions of the present invention comprise dichlorinated heterocyclic compounds, including dichloroflosequinan. The methods of the present invention also comprise the synthesis of dichloroflosequinan.

专利号:US-6872831-B2
优先权日:2002-03-01
标题:Carboxylated heterocyclic compounds and methods of synthesis
发明人：KWIATKOWSKI STEFAN; GOLINSKI MIROSLAW
权利人:R T ALAMO VENTURES I LLC
摘要:Compositions of the present invention comprise carboxylated heterocyclic compounds, including carboxyflosequinan. The methods of the present invention also comprise the synthesis of carboxyflosequinan.

专利号:US-7084275-B2
优先权日:2001-10-25
标题 :Stereospecific enrichment of heterocyclic enantiomers
发明人：KWIATKOWSKI STEFAN; GOLINSKI MIROSLAW; KUPPER JOSEPH
权利人:R T ALAMO VENTURES I LLC
摘要:The present invention describes methods for the stereoselective synthesis of heterocyclic enantiomers. The methods of the present invention incorporate the stereo-preferred oxidation of quinolone thiomethyl intermediates by optically active camphor based oxaziridines to provide R(+) or S(−) quinolone methylsulfinyl derivatives.