烯丙基三乙氧基硅烷置于ch3Mgbr体系中,用 Not Given 作为反应溶剂,化学反应生成 烯丙基三甲基硅烷 参考文献:The Reaction Of Mercaptans With Alkenyl Silanes 标题:The Reaction Of Mercaptans With Alkenyl Silanes 摘要: DOI:10.1021/ja01159A007
专利号:WO-2024012791-A1 优先权日:2022-07-11 标题 :Electrochemical synthesis of pyrazolines and pyrazoles 发明人:BÄR ROBIN MAXIMILIAN; FORD MARK JAMES; KALDAS SHERIF JAMES; WALDVOGEL SIEGFRIED; HOFMANN SILJA; LINDEN MARTIN 权利人:BAYER AG 摘要:The present invention relates to an electrochemical process for the synthesis of pyrazolines and pyrazoles of formula (I). The process can be especially used for the synthesis of the herbicide safener mefenpyr-diethyl.
专利号:US-9783549-B2 优先权日:2013-11-04 标题:Macrocyclization reactions and intermediates useful in the synthesis of analogs of halichondrin B 发明人:FANG FRANCIS G; KIM DAE-SHIK; CHOI HYEONG-WOOK; CHASE CHARLES E; LEE JAEMOON 权利人:EISAI R&D MAN CO LTD 摘要:The invention provides methods for the synthesis of eribulin or a pharmaceutically acceptable salt thereof (e.g., eribulin mesylate) through a macrocyclization strategy. The macrocyclization strategy of the present invention involves subjecting a non-macrocyclic intermediate to a carbon-carbon bond-forming reaction (e.g., an olefination reaction (e.g., Homer-Wadsworth-Emmons olefination), Dieckmann reaction, catalytic Ring-Closing Olefin Metathesis, or Nozaki-Hiyama-Kishi reaction) to afford a macrocyclic intermediate. The invention also provides compounds useful as intermediates in the synthesis of eribulin or a pharmaceutically acceptable salt thereof and methods for preparing the same.
专利号:US-2023174477-A1 优先权日:2021-12-03 标题:Methods for synthesis of the tricyclic prostaglandin d2 metabolite methyl ester 发明人:DAI MINGJI; SIMS HUNTER 权利人:PURDUE RESEARCH FOUNDATION 摘要:Methods for the synthesis of a tricyclic-prostaglandin D 2 metabolite methyl ester or a pharmaceutically acceptable salt thereof.
专利号:US-9802909-B2 优先权日:2016-01-27 标 题:Enantioselective process for synthesis of (+)- petromyroxol and its diastereomers 发明人:RAMANA CHEPURI VENKATA; Mullapudi Venkannababu 权利人:COUNCIL SCIENT IND RES 摘要:An enantioselective process for the synthesis of (+)-petromyroxol and its Diastereomers from (3aR,5R,6aR)-2,2-dimethyl-5-((R)-oxiran-2-yl)tetrahydrofuro[2,3-d][1,3]dioxole.
专利号:US-5338865-A 优先权日:1992-03-12 标 题 :Synthesis of halichondrin B and norhalichondrin B 发明人:KISHI YOSHITO; FANG FRANCIS; FORSYTH CRAIG J; SCOLA PAULA M; YOON SUK KYOON 权利人:HARVARD COLLEGE 摘要:Novel chemical compounds that can be used to synthesize halichondrin B and norhalichondrin B, and related derivatives, are described. The synthesis of halichondrin B and norhalichondrin B from these compounds also is described.
专利号:US-2012101271-A1 优先权日:2010-10-22 标题 :Diamine synthesis via catalytic c-h amination of azides 发明人:ZHANG X PETER; LU HONGJIAN 权利人:ZHANG X PETER; LU HONGJIAN 摘要:Selective intramolecular C—H amination via metalloradical activation of azides: synthesis of 1,3-diamines under neutral and nonoxidative conditions. One aspect of the present invention is the synthesis of 1,3-diamines by intramolecular C—H amination of sulfamoyl azides. More specifically, sulfamoyl azides may be selectively aminated via metalloradical activation of azides, preferably with Co(II) porphyrins. In a particularly preferred embodiment, the Co(II) porphyrin is a D 2h -symmetric porphyrin.
参考标题:First Enantioselective Total Synthesis Of The Reported Structure Of (R)-(+)-Orizaterpenyl Benzoate Using An Asymmetric Allylation Of A Prochiral Ketone In A Domino Process 作者:Lutz Tietze,Simon Biller,Thomas Wolfram |发布日期:2010.9 摘要:An Efficient Synthesis Of (R)-Orizaterpenyl Benzoate Using A Multicomponent Domino Allylation Reaction Of A Prochiral Ketone With Allyltrimethyl Silane And The Enantiopure Silyl Ether Of Benzyl Phenyl Carbinol In The Presence Of Catalytic Amounts Of Tfoh Is Described.
合成参考文献
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