CAS: 64536-78-3; (1,5-Cyclooctadiene)(Pyridine)(Tricyclohexylphosphine)-Iridium(I) Hexafluorophosphate

该化合物是一种定义明确的(I)复合物,广泛用于同质催化和有机金属研究.其主要优点包括在惰性条件下高度稳定性和催化应用的多功能性,特别是在氢化和C-H活性反应中.三环己二酚的存在会增加...

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合成工艺路线路线简述

  • 合成目标产物 (1,5-Cyclooctadiene)(Pyridine)(Tricyclohexylphosphine)Iridium(I) Hexafluorophosphate 主要起始原料 Bis(Pyridine)(1,5-Cyclooctadiene)Iridium(I) Hexafluorophosphate, 99% And Tricyclohexyl Phosphine
  • (文献来源)合成步骤主要原料 Bis(Pyridine)(1,5-Cyclooctadiene)Iridium(I) Hexafluorophosphate, 99% 和 Tricyclohexyl Phosphine
(1,5-Cyclooctadiene)Bis(Pyridine)Iridium(I) Hexafluorophosphate,三环己基膦 以 甲醇作为反应溶剂,反应 1.0H,以79%的收率获得crabtree'S Catalyst
参考文献:铱(I)N-杂环卡宾(Nhc)/膦催化剂用于轻度和化学选择性加氢工艺
标题:铱(I)N-杂环卡宾(Nhc)/膦催化剂用于轻度和化学选择性加氢工艺
摘要:已经通过使用铱(I)催化剂建立了烯烃的定向化学选择性加氢,该催化剂具有可调节的nhc /膦配体组合.该选择性还原过程已在多种溶剂(包括更环境可接受的介质)中得到证明,还允许进一步提高氢化选择性.
Doi:10.1002/Chem.201504825

专利信息


专利号:WO-2023039068-A1
优先权日:2021-09-08
标题:Compositions and methods for synthesis of peptide nucleic acid intermediates
发明人:COULL JAMES M; GILDEA BRIAN D
权利人:NEUBASE THERAPEUTICS INC
摘要:The present disclosure provides intermediates for the synthesis of peptide nucleic acid (PNA) backbones and monomers, such as cyclic intermediates, and methods of making the same.

专利号:WO-2024054871-A1
优先权日:2022-09-07
标题:Methods of producing 2,3,5,6-alkyl-1,4-benzoquinones
发明人:TANG XIUBO; FU GUOLIANG; SHU LIANHE; GIANNOUSIS PETER; CHEN ZHONGJING; SUN BAOQUAN; WU GUOKA; GU JIANCAI
权利人:PTC THERAPEUTICS INC
摘要:The application discloses methods useful for the synthesis of certain 2,3,5,6-alkyl-1,4-benzoquinone compounds, including 2,3,5-trimethyl-6-nonylcyclohexa-2,5-diene-1,4-dione, and synthetic intermediates for the production thereof.

专利号:WO-2024126692-A1
优先权日:2022-12-15
标题 :Peracid promoters in the iridium-catalyzed hydrosilylation synthesis of haloalkylorganosilanes
发明人:SCHOLZ HENRIK; KROKE EDWIN; KRAUSHAAR KONSTANTIN; GLATZER HOLGER JÜRGEN; LEWIS KENRICK MARTIN; WAGNER ROLAND
权利人:MOMENTIVE PERFORMANCE MAT GMBH
摘要:The present invention is directed at a process for producing a compound of Formula (I): (R1)y(R2O)3-ySiCH2CHR3CR4R5X comprising reacting (a) an olefinic halide; (b) an alkoxysilane; (c) a catalytically effective amount of iridium-containing catalyst; and (d) a reaction-promoting effective amount of a peroxycarboxylic acid to produce the product of Formula (I).

专利号:US-11584754-B2
优先权日:2016-06-08
标 题 :Derivatives of thailanstatin A, methods of treatment and methods of synthesis thereof
发明人:NICOLAOU KYRIACOS C; RHOADES DEREK; KUMAR SOUNDARAPANDIAN M; PATTANAYAK MANAS R; LAMANI MANJUNATH
权利人:UNIV RICE WILLIAM M
摘要:In one aspect, the present disclosure provides analogs of thailanstatin of the formula wherein the variables are as defined herein. In another aspect, the present disclosure also provides methods of preparing the compounds disclosed herein. In another aspect, the present disclosure also provides pharmaceutical compositions and methods of use of the compounds disclosed herein.

专利号:US-2025051298-A1
优先权日:2023-08-09
标 题:Continuous flow chemistry for synthesis of cannabinoids
发明人:RAMIREZ GIOVANNI A; TESFATSION TESFAY T; CRUCES IVAN; HELLMANN ADAM J; RAY KYLE P; CRUCES WESTLEY
权利人:COLORADO CHROMATOGRAPHY LLC
摘要:Continuous flow chemistry processes are disclosed herein. The continuous flow processes can be used to produce tetrahydrocannabinol from a cannabidiol starting material. The continuous flow processes can also be used to produce hexahydrocannabinol from a tetrahydrocannabinol starting material. Multiple flow chemistry reactor systems can be combined to produce hexahydrocannabinol from a cannabidiol starting material. The continuous flow processes can be used to produce the desired products at kilogram scales within minutes.

专利号:EP-4634196-A1
优先权日:2022-12-15
标题 :Peracid promoters in the iridium-catalyzed hydrosilylation synthesis of haloalkylorganosilanes
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合成参考文献


参考文献:10.1134/s1066362210010212
摘要:Shevchenko VP, Nagaev IY, Myasoedov NF. Hydrogen isotope labeling of PTC124. Radiochemistry. 2010 Feb;52(1):95–8. doi: 10.1134/s1066362210010212.
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