4-溴-2,3-二氯苯胺 反应生成 2,3-二氯溴苯 参考文献:Hurtley,Journal Of The Chemical Society,1901,Vol. 79,P. 1303 标题:Hurtley,Journal Of The Chemical Society,1901,Vol. 79,P. 1303
专利号:US-2006111438-A1 优先权日:2004-10-21 标 题:Asymmetric synthesis of substituted dihydrobenzofurans 发明人:GONTCHAROV ALEXANDER V; KHAFIZOVA GULNAZ; POTOSKI JOHN R; YU QING; SHAW CHIA-CHENG; STACK GARY P; ZHOU DAHUI 权利人:WYETH CORP 摘要:The present invention concerns production of a compound of the formula n n nor a pharmaceutically acceptable salt thereof by a process which utilizes the cyclization of a compound of the formula: n n nwhere Ar, Y, R 1 , R y , R 2 , and m are as defined herein.
专利号:AU-2005299884-A1 优先权日:2004-10-21 标 题 :Asymmetric synthesis of substituted dihydrobenzofurans
专利号:JP-2008517919-A 优先权日:2004-10-21 标题 :Asymmetric synthesis of substituted dihydrobenzofurans.
专利号:US-9850204-B2 优先权日:2008-12-16 标 题:Triple reuptake inhibitors and methods of their use 发明人:SHAO LIMING; WANG FENGJIANG; MALCOLM SCOTT C; HEWITT MICHAEL C 权利人:SUNOVION PHARMACEUTICALS INC 摘要:Provided herein are bicyclic compounds and methods of synthesis thereof. The compounds provided herein are useful for the treatment, prevention, and/or management of various neurological disorders. Compounds provided herein inhibit reuptake of endogenous monoamines, such as dopamine, serotonin and norepinephrine (e.g., from the synaptic cleft) and modulate one or more monoamine transporter. Pharmaceutical formulations containing the compounds are also provided.
专利号:EP-1802597-A1 优先权日:2004-10-21 标题:Asymmetric synthesis of substituted dihydrobenzofurans
专利号:WO-2006047228-A1 优先权日:2004-10-21 标题 :Asymmetric synthesis of substituted dihydrobenzofurans
[参考文献]: M Arivazhagan, Et Al. Pcm/td-Dft Analysis Of 1-Bromo-2,3-Dichlorobenzene--A Combined Study Of Experimental (Ft-Ir And Ft-Raman) And Theoretical Calculations. Spectrochim Acta A Mol Biomol Spectrosc. 2013 Mar 15:105:497-508.
合成参考文献
参考文献:10.1007/978-3-642-90675-6_8 参考文献:10.1007/978-3-030-18252-6_5 摘要:Fleming I, Williams D. 2D-Nuclear Magnetic Resonance Spectra. 2019. In: Spectroscopic Methods in Organic Chemistry. 参考文献:10.1055/s-0040-1719851 摘要:Lim HN, Hong WP, Shin I. 1,4-Azaborines: Origin, Modern Synthesis, and Applications as Optoelectronic Materials. Synthesis. 2021 Nov 04;54(03):570–88. doi: 10.1055/s-0040-1719851. 参考文献:10.1007/978-3-662-33911-4_2