CAS: 3482-57-3; (2S,3R,4S,5S,6R)-2-(((2R,3S,4R,5R,6S)-4,5-Dihydroxy-2-(Hydroxymethyl)-6-(4-Nitrophenoxy)Tetrahydro-2H-Pyran-3-yl)Oxy)-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-3,4,5-Triol

该化合物是一种甘蓝化合物,其特点是有硝基苯基组和两组甘蓝相色体,其典型的颜色是硝基酸组的黄色,该化合物还能够影响其溶解性和再活性,可溶于水和甲醇等极地溶剂,使其在各种生物化学应用中有用.该分子中的甘蓝结合在某些条件下有助于其稳定性和对水解的耐受性,尽管在生物系统中可以发生酶裂变.该化合物经常用于酶分析,特别是用于研究甘蓝活动,因为硝基营养酚的释放可以很容易地监测光谱学学.此外,其结构特征使它在碳水化合物化学和生物化学过程中成为一种有价值的工具,用于推进甘蓝糖酶反应过程.

结构式图片

上下游产品

CAS号69948-03-4 对硝基苯基β-D-芹菜素七乙酸酯 | CAS号2106-10-7 α-D-氟代吡喃葡萄糖 | CAS号2492-87-7 4-硝基苯基-β-D-吡喃葡萄糖苷 | CAS号5328-50-7 Altropyranose, ... | CAS号133-99-3 D(+)-纤维二糖 | CAS号83-87-4 α,β-D-五乙酸葡萄糖 | CAS号5987-78-0 对硝基苯基 2,3,4,6-O... | CAS号100-02-7 对硝基苯酚 | CAS号604-69-3 β-D-葡萄糖五乙酸酯 | CAS号106927-48-4 4-硝基苯基-β-D-纤维三糖苷 | CAS号129411-62-7 P-硝基苯基 B-D-纤维四糖苷 | CAS号100-02-7 对硝基苯酚 | CAS号133-99-3 D(+)-纤维二糖 | CAS号3767-28-0 4-硝基苯-Α-D-葡吡喃糖苷 | CAS号492-62-6 α-D-葡萄糖 | CAS号619-08-9 2-氯-4-硝基酚 | CAS号6401-81-6 α-D-Glcp-(1->4)... | CAS号2492-87-7 4-硝基苯基-β-D-吡喃葡萄糖苷 | CAS号42935-24-0 4-氨基苯基-Β-D-吡喃纤维二糖苷

合成工艺路线路线简述

    Hepta-O-Acetyl-β-Maltosyl Chloride置于sodium Methylate体系中,用 甲醇,六甲基磷酰三胺 用作溶剂,化学反应 6.0H,反应生成对硝基苯基麦芽糖苷
    参考文献:Apparu,Maecel; Blanc-Muesser,Michele; Defaye,Jacques,Canadian Journal Of Chemistry,1981,Vol. 59,P. 314-320
    标题:Apparu,Maecel; Blanc-Muesser,Michele; Defaye,Jacques,Canadian Journal Of Chemistry,1981,Vol. 59,P. 314-320

    海关参考信息

    专利信息


    专利号:WO-2024103123-A1
    优先权日:2022-11-17
    标题 :The synthesis of omapatrilat
    发明人:VITALE ROMINA; MARTIN VINCENT ALEXANDRE; FABER WIJNAND; SOMMER ROMAN
    权利人:ENDOTHELIUM SCANNING NANOTECHNOLOGY LTD
    摘要:Described herein are improved methods of making Compound 1 (4S,7S,10aS)-4-((S)-2- mercapto-3-phenylpropanamido)-5-oxooctahydro-7H-pyrido[2,1-b][1,3]thiazepine-7-carboxylic acid, or Omapatrilat, and purified Omapatrilat obtained from the improved methods.

    专利号:WO-8404041-A1
    优先权日:1983-04-14
    标 题 :Colon-specific drug delivery system
    发明人:FRIEND DAVID ROBERT; CHANG GEORGE WASHINGTON
    权利人:UNIV CALIFORNIA
    摘要:A colon-specific drug delivery system based on the use of a synthetic drug glycoside prodrug composition which, when ingested by a mammal, undergoes reaction with glycosidases produced by colonic microflora to release a free drug capable of being absorbed to or absorbed by the colonic mucosa. Synthesis of synthetic drug glycosides useful in the present drug delivery system is illustrated in figure 1. In that figure, 'a' is Ag2CO3, molecular sieve, CCl4; 'b' is 0.01 N NaOH, MeOH; and 'c' is betaglucosidase; the numerals 3, 4, 23, 14, 15, 1 and 2 denote compounds 3, 4, 23, 14, 15, 1 and 2 respectively; the letter R means radical and the letters Ac mean acetyl. The other letters, e.g., O, H, F and Br denote the chemical elements oxygen, hydrogen, fluorine and bromine, respectively.

    专利号:EP-4619408-A1
    优先权日:2022-11-17
    标题 :The synthesis of omapatrilat

    专利号:RU-2238974-C2
    优先权日:2001-09-06
    标题:Dna fragment of mycelial fungus penicillium verruculosum encoding synthesis of secretable endoglucanase iii and group of penicillium canescens strains producing penicillium verruculosum endoglucanase iii constructed by methods of transformation and genetic engineering based on this dna fragment
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    主要参考文献

    参考标题:Synthesis Of Complex Oligosaccharides By Using A Mutated (1,3)--D-Glucan Endohydrolase From Barley
    作者:Jon K. Fairweather,Maria Hrmova,Simon J. Rutten,Geoffrey B. Fincher,Hugues Driguez |发布日期:2003.6.6
    摘要:Complex Oligosaccharides With Newly Formed (1,3)-Beta-Glycosidic Linkages Were Obtained In Good To Excellent Yields When Substituted Or Unsubstituted Alpha-Laminaribiosyl Fluorides, Acting As Donors, Were Condensed Onto Mono- And Disaccharide Beta-D-Hexopyranoside Acceptors By Using A (1,3)-Beta-D-Glycosynthase. These Linear And Branched (1,3)-Beta-Linked Oligosaccharides Could Prove To Be Important

    合成参考文献


    参考文献:10.1080/00021369.1991.10870897|10.1271/bbb1961.55.1959
    摘要:Haga K, Kitaoka M, Kashiwagi Y, Sasaki T, Taniguchi H. Purification and Properties of a Xylanase fromCellvibrio gilvusThat Hydrolyzesp-Nitrophenyl Cellooligosaccharides. Agricultural and Biological Chemistry. 1991 Aug;55(8):1959–67. doi: 10.1080/00021369.1991.10870897.
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