CAS: 202402-01-5; 4-Methoxy-N-(4-(Trifluoromethyl)Benzyl)Butanamide
- 英文名称4-Methoxy-N-(4-(Trifluoromethyl)Benzyl)Butanamide
- 中文名称4-甲氧基-N-(4-(三氟甲基)苄基)丁酰胺
- IUPAC名称4-methoxy-N-(4-(trifluoromethyl)benzyl)butanamide
- 其它别名Get-73; Get 73; Get-73; Get73; Gamma Hydroxybutyric Acid Analogue; 4-Methoxy-N-(4-(Trifluoromethyl)Benzyl)Butanamide; Neuroprotective,Anti-Alcohol,Inhibit,γ-Hydroxybutyric Acid,Mglur5,Ghb,Inhibitor,Get73,Get-73,Anxiolytic,Glutamate; Butanamide, 4-Methoxy-N-[[4-(Trifluoromethyl)Phenyl]Methyl]-; 4-Methoxy-N-[[4-(Trifluoromethyl)Phenyl]Methyl]Butanamide; Get73, 10 Mm In Dmso
- CAS编号202402-01-5
- MFCD编号:MFCD31812537
- EINECS号:805-308-6
- FDA UNII编号:U5CLZ223FH
- 分子式:C13H16F3NO2分子量:275.27
- 产品CID: 1027696
- 产品分类Chemistry → Organic Building Blocks → Benzene Compounds
物理性质
MSDS等安全信息
欧盟法规
ECHA物质C&L通报合成工艺路线路线简述
海关参考信息
- 2902300000-甲苯
2905121000-正丙醇
2905130000-正丁醇
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主要参考文献
1. Haass-Koffler CL, Goodyear K, Long VM, Tran HH, Loche A, Cacciaglia R, Swift RM, Leggio L. A Phase I randomized clinical trial testing the safety, tolerability and preliminary pharmacokinetics of the mGluR5 negative allosteric modulator GET 73 following single and repeated doses in healthy volunteers. Eur J Pharm Sci. 2017 Nov 15;109:78-85. doi: 10.1016/j.ejps.2017.07.031. Epub 2017 Aug 1. 2. Haass-Koffler CL, Goodyear K, Long VM, Tran HH, Loche A, Cacciaglia R, Swift RM, Leggio L. Dataset for Phase I randomized clinical trial for safety and tolerability of GET 73 in single and repeated ascending doses including preliminary pharmacokinetic parameters. Data Brief. 2017 Sep 17;15:407-413. doi: 10.1016/j.dib.2017.09.018.合成参考文献
摘要:S55 | ZINC15PHARMA | Pharmaceuticals from ZINC15 | DOI:10.5281/zenodo.3247749
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