CAS: 16533-72-5; Cis-Epoxysuccinic Acid

上下游产品

benzene-1,2-diol maleic acid hydroquinone p-benzoquinone(2R,3S)-dimethyl oxirane-2,3-dicarboxylate meso-epoxy-succinyl chloridemeso-epoxy-succinyl chloride N-(DL-α-Methyl-benzyl)-threo-β-hydroxy-DL-asparaginsaeure DL-threo-β-hydroxyaspartic acid

专利信息

专利号:WO-9213549-A1
优先权日:1991-02-07
标题:Inhibition of cell proliferation by hydrophobic peptides
发明人：HATHAWAY DAVID R; MARCH KEITH L
权利人:RES CORP TECHNOLOGIES INC
摘要:The present invention is directed a method of using certain hydrophobic peptides for the inhibition of cell proliferation, wherein the peptides have the general formula: R-Xaa1-(Xaa)m-Xaac. The subject peptides have 2-7 amino acids such as alanine (Ala), arginine (Arg), cysteine (Cys), isoleucine (Ile), leucine (Leu), lysine (Lys), methionine (Met), norleucine (nLeu), phenylalanine (Phe), proline (Pro), threonine (Thr), tyrosine (Tyr), tryptophan (Trp), or valine (Val). In accordance with the present invention, these peptides are potent inhibitors of cell proliferation as well as inhibitors of the synthesis of two cellular proto-oncogenes. One aspect of the present invention provides for the prevention and treatment of cancer by administration of the subject peptides. A further aspect of the present invention provides for inhibiting cell proliferation using the subject peptides in the treatment and prevention of prostatic hypertrophy, arterial occlusion (restenosis), arteriosclerosis, and smooth muscle cell diseases.

专利号:US-9109084-B1
优先权日:2014-09-18
标题:Synthesis of polyepoxy succinic acid compounds using free radical initiators
发明人：ROSE DAVID JAY; ZAID GENE H; BURGOYNE THOMAS W; BRASHEAR KIM
权利人:JACAM CHEMICAL COMPANY 2013 LLC
摘要:Methods of synthesizing polymers including repeat units of the formula n ncomprise the step of polymerizing repeat units of the formulan n nin the presence of a free radical catalyst, where each R and each M is separately and independently selected from the group consisting of H, C1-C12 straight or branched chain alkyl, aryl, amine, amide, and ester groups, halides, and mixtures thereof, and n ranges from about 2-15.

专利号:US-2009111737-A1
优先权日:1999-05-24
标题:Novel antibacterial agents
发明人：CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
权利人:CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
摘要:This invention relates to novel multibinding compounds (agents) that are antibacterial agents. The multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands in their monovalent (i.e., unlinked) state have the ability to bind to a an enzyme involved in cell wall biosynthesis and metabolism, a precursor used in the synthesis of the bacterial cell wall and/or the bacterial cell surface thereby interfere with the synthesis and/or metabolism of the cell wall. In particular the multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands hasn a ligand domain capable of binding to penicillin binding proteins, a transpeptidase enzyme, a substrate of a transpeptidase enzyme, a beta-lactamase enzyme, pencillinase enzyme, cephalosporinase enzyme, a transglycoslase enzyme, or a transglycosylase enzyme substrate; Preferably, the ligands are selected from the beta lactam or glycopeptide class of antibacterial agents.

专利号:US-4794108-A
优先权日:1984-04-24
标题:1-carboxymethoxy acetidinones and their production
发明人：KISHIMOTO SHOJI; SENDAI MICHIYUKI; OCHIAI MICHIHIKO
权利人:TAKEDA CHEMICAL INDUSTRIES LTD
摘要:A 2-azetidinone derivative having a group of the formula wherein R1 and R2 are the same or different and each represents a hydrogen atom, alkyl, aryl or arylalkyl which may have a substituent at the 1-position and an amino group, at the 3-position, which may be acylated or protected, its salt or ester, and methods of producing the same, (1) a method comprising subjecting a 2-azetidinone derivative having a group of the formula wherein the symbols are as defined above at the 1-position and an amino group at the 3-position, its salt or ester to an acylation or protective-group introduction reaction, and (2) a method comprising reacting a 2-azetidinone derivative having a hydroxy group at the 1-position and an amino group, at the 3-position, which may be acylated or protected, or its salt with a compound of the formula wherein W is a halogen atom; other symbols are as defined above, its salt or ester. The above objective compounds are utilizable as excellent antimicrobial agents or as valuable intermediates for the synthesis of the same.

专利号:CN-110591954-B
优先权日:2019-09-25
标 题:Sphingobacterium and application and method thereof in catalytic synthesis of L (+) -tartaric acid or salt thereof

专利号:CN-1524893-A
优先权日:2003-02-28
标 题:A kind of synthesis of polyepoxysuccinate