CAS: 1620-75-3; 6-Methylpicolinonitrile

相似化合物

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上下游产品

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2,6-二甲基吡啶置于亚硝酸特丁酯,N-羟基邻苯二甲酰亚胺,Palladium Diacetate体系中,用 乙腈 用作溶剂,化学反应 24.0H,以54%的收率获得6-甲基-2-吡啶腈
参考文献:钯(II)催化将甲基芳烃直接转化为芳族腈
标题:钯(II)催化将甲基芳烃直接转化为芳族腈
摘要:从甲基到腈:使用pd(oac)2和n-羟基邻苯二甲酰亚胺(nhpi)作为催化剂,亚硝酸叔丁酯作为氮源,开发了一种温和的氨氧化方法,该方法将甲基芳烃直接转化为芳族腈.氧化剂.
Doi:10.1002/anie.201305731

专利信息

专利号:WO-2013056547-A1
优先权日:2011-10-22
标题 :Synthesis of a group of hydantoin derivatives and use thereof
发明人：CHEN DEGUI
权利人:CHEN DEGUI
摘要:Provided in the present invention are the pharmaceutical composition, synthesis procedure and medicinal use of a group of HYDANTOIN derivatives. Since these compounds have an inhibiting effect on an androgen receptor, the compounds can be used to treat prostate cancer and other diseases and physiological disorders related to androgen receptor activity.

专利号:US-8772301-B2
优先权日:2009-12-18
标题 :Compounds for treating disorders mediated by metabotropic glutamate receptor 5, and methods of use thereof
发明人：HARDY LARRY WENDELL; HEFFERNAN MICHELE L R; WU FRANK XINHE; SPEAR KERRY L; SARASWAT LAKSHMI D
权利人:HARDY LARRY WENDELL; HEFFERNAN MICHELE L R; WU FRANK XINHE; SPEAR KERRY L; SARASWAT LAKSHMI D; SUNOVION PHARMACEUTICALS INC
摘要:Provided herein are compounds and methods of synthesis thereof. The compounds set forth herein are useful for the treatment, prevention, and/or management of various disorders, such as neurological disorders, neurodegenerative disorders, neuropsychiatric disorders, disorders of cognition, learning or memory, gastrointestinal disorders, lower urinary tract disorder, and cancer. Compounds set forth herein modulate the activity of metabotropic glutamate receptor 5 (mGluR5) in the central nervous system or the periphery. Pharmaceutical formulations containing the compounds and their methods of use are also provided herein.

专利号:WO-2023114200-A2
优先权日:2021-12-14
标题 :Methods for the synthesis of complement factor d inhibitors and intermediates thereof

专利号:WO-2023114198-A2
优先权日:2021-12-15
标题 :Methods for the synthesis of complement factor d inhibitors