CAS: 16110-10-4; Acetaminophen Glucuronide

上下游产品

O1-(4-amino-phenyl)-β-D-glucopyranuronic acidO1-(4-amino-phenyl)-β-D-glucopyranuronic acid acetic anhydride 4-acetaminophenol UDP-glucuronic acid uronatemethyl 4-(acetamido)phenyl 2,3,4-tri-O-acetyl-β-D-glucopyranosiduronate

📜3,4,6-三邻乙酰基-Alpha-D-吡喃葡萄糖 1,2-(原酸甲酯)置于水体系中,用 四氢呋喃,甲醇,二氯甲烷 用作溶剂,化学反应 20.5H,反应生成对乙酰氨基酚葡糖苷酸
参考文献:Preparation And Characterisation Of Solid State Forms Of Paracetamol-O-Glucuronide
标题:Preparation And Characterisation Of Solid State Forms Of Paracetamol-O-Glucuronide
摘要:The Synthesis And Crystallisation Of The Pharmaceutically Important Metabolite,Paracetamol-O-Glucuronide,Is Described. Hydrated And Anhydrous Forms Of The Target Molecule Have Been Characterised By Pxrd,Dsc And Tga. In Addition,A Methanol Solvate Has Been Analysed,Including Single Crystal Analysis,Which Represents The First Structure Solution For This System. (C) 2011 Elsevier Ltd. All Rights Reserved.
Doi:10.1016/j.Carres.2011.12.018

专利信息

专利号:US-2006131160-A1
优先权日:2002-11-26
标题:Method of preparing dendrons and dendrimers with heterocyclic substructures of imino-ethers and derivatives using non-standard means and microwaves
发明人：MARRERO TERRERO ALMA L; CONTRERAS ALARCON ORESTES R
权利人:CNIC CT NAC INVESTIGACIONES
摘要:Dendrons and dendrimers are prepared by synthetic procedures under microwaves starting from heterocyclic substructures of C2 and C4 substituted iminoethers or from their boronic, sulfonic and phosphoric derivatives, or from their N-substituted derivatives, cyclic and acyclics, their products of hydrolysis or the transformations of them in other pentagonal nitrogenated heterocycles with incorporation in some cases, of structural units of chromogenic or fluorogenic glucuronides in their cavities or in the dendrimeric surface, in dependence of the functionality of the outlying groups. Starting from different reactions of the iminoetheres with carboxylic acids, anhydrides, esters, bases, aldehydes, alkyl halides, amines, isocyanates, aromatic thiols, by pyrolysis or hydrolysis, in sequences of selected reactions, alternated and iteratives, with the use of procedures and non classic methods of synthesis under microwaves at power between 30 and 300 Watt at 2450 MHz, to achieve the formation of basic substructures for the construction of dendrons, arms or ramifications of dendritic structures of different generations, from G0 to G4, by a convergent strategy, in presence or absence of solvents and/or polymeric or mineral solid supports.

专利号:AU-2003281910-A1
优先权日:2002-11-26
标 题 :Procedure for synthesis of dendrons and dendrimers under microwaves