CAS: 127979-74-2; 2-(Trifluoromethoxy)Benzamide

该化合物是一种有机化合物,其特点是在正硫位置上存在一种苯胺功能组,代之以三氟甲基苯氧组;该化合物的特点是,一种苯环与一个碳基(氨)组捆绑在一起,以及一种三氟甲基苯氧组,由三氢原子由氟氧原子取代;三氟甲基苯氧替代具有独特的电子和消毒特性,使该化合物在各种应用中,包括在制药和农用化学中具有潜在用途;氟基原子的存在增强了该化合物的脂性及代谢性稳定性,这可能会影响其生物活动;此外,该化合物可能由于具有很强的C-F联系而表现出有趣的热和化学稳定性.该化合物的溶性和再活性因溶剂和条件而不同,因此其溶剂和再活性可能因溶剂和物质条件而不同,从而成为合成有机化学和材料科学的一个主题.

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benzamide bis(trifluoromethyl)peroxide N-[3',5'-dimethyl-2-(5-methylbenzoxazol-2-yl)biphenyl-4-yl]-2-trifluoromethoxybenzamide

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    专利号:EP-4630405-A1
    优先权日:2022-12-06
    标题 :Process for the synthesis of substituted tetrahydrofuran modulators of sodium channels

    专利号:WO-2024123815-A1
    优先权日:2022-12-06
    标 题:Process for the synthesis of substituted tetrahydrofuran modulators of sodium channels

    专利号:US-8372971-B2
    优先权日:2004-08-25
    标 题:Heterocyclic compounds and methods of use
    发明人：WRASIDLO WOLFGANG; DNEPROVSKAIA ELENA
    权利人:TARGEGEN INC; WRASIDLO WOLFGANG; DNEPROVSKAIA ELENA
    摘要:Heterocyclic compounds derived from benzotriazine, triazines, triazoles and oxadiazoles are disclosed. The methods of synthesis and of use of such heterocyclic compounds are also provided.

    专利号:WO-2012014127-A1
    优先权日:2010-07-30
    标 题:5-lipoxygenase inhibitors
    发明人：VERMA ASHWANI KUMAR; MALHOTRA SANJAY; GHORPADE SATISH MADHAV; DAWANGE MAHESH BALASAHEB; RAY ABHIJIT; GUPTA SUMAN; SRIVASTAVA PUNIT; DASTIDAR SUNANDA GHOSH
    权利人:RANBAXY LAB LTD; VERMA ASHWANI KUMAR; MALHOTRA SANJAY; GHORPADE SATISH MADHAV; DAWANGE MAHESH BALASAHEB; RAY ABHIJIT; GUPTA SUMAN; SRIVASTAVA PUNIT; DASTIDAR SUNANDA GHOSH
    摘要:The present invention relates to sulfonamides derivatives as 5-lipoxygenase (5-LO) inhibitors and a process for their synthesis. The present invention also relates to pharmacological compositions containing these sulfonamides derivatives, as well as methods of treating bronchial asthma, chronic obstructive pulmonary disease, rheumatoid arthritis, multiple sclerosis, Type I diabetes, psoriasis, allograft rejection, inflammatory bowel disease, ulcerative colitis, acne, atherosclerosis, cancer, pruritis, allergic rhinitis and other inflammatory and/or autoimmune disorders.

    专利号:CN-105237460-B
    优先权日:2015-10-29
    标 题:One-step synthesis method of 2-acyl substituted isoindoline-1-one compounds

    专利号:CN-105237460-A
    优先权日:2015-10-29
    标题:One-step synthesis method of 2-acyl substituted isoindoline-1-one compounds

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    摘要:Yerien, D. E.; Barata-Vallejo, S.; Postigo, A., Science of Synthesis: Modern Strategies in Organofluorine Chemistry , (2024) 1, 9.
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