CAS: 10229-10-4; Pent-3-Yn-1-Ol

上下游产品

CAS号927-74-2 3-丁炔-1-醇 | CAS号74-88-4 碘甲烷 | CAS号98689-60-2 pent-3-ynoxymet... | CAS号79322-55-7 tetrahydro-2-[(... | CAS号22377-43-1 3-戊酸甲酯 | CAS号5963-77-9 2-戊炔酸 | CAS号36781-65-4 戊-3-炔酸 | CAS号55314-57-3 2-戊炔酸乙酯 | CAS号1474-33-5 Pentanoic acid,... | CAS号54106-83-1 pent-3-ynyl tri... | CAS号106060-18-8 methanesulfonic... | CAS号22377-43-1 3-戊酸甲酯 | CAS号18719-27-2 3-PENTYNYLBROMIDE | CAS号764-38-5 2-甲巯基吩噻嗪 | CAS号71-41-0 正戊醇 | CAS号763-89-3 甲基-3-戊烯-1-醇 | CAS号132699-38-8 benzoic acid,pe... | CAS号33698-68-9 hepta-1,5-dien-3-one | CAS号3329-88-2 3-Pentyn-1-ol,1... | CAS号326891-18-3 pent-3-ynoxy-di...

2-戊炔酸置于氢氧化钾,Lithium Aluminium Tetrahydride,水体系中,用 乙醚 用作溶剂,化学反应 3.0H,反应生成3-戊炔-1-醇
参考文献:Solvolysis Of 1-Pent-3-Ynyl Triflate. Mechanism Of The Homopropargyl Rearrangement
标题:Solvolysis Of 1-Pent-3-Ynyl Triflate. Mechanism Of The Homopropargyl Rearrangement
摘要:
Doi:10.1021/ja00399A036

专利信息

专利号:US-11912647-B2
优先权日:2020-05-22
标 题:Diversity-oriented synthesis of N,N,O-trisubstituted hydroxylamines from alcohols and amines by N—O bond formation
发明人：CRICH DAVID; HETTIKANKANAMALAGE ASIRI; HILL JARVIS
权利人:UNIV GEORGIA
摘要:In one aspect, the disclosure relates to a method for the direct synthesis of complex N,N,O-trisubstituted hydroxylamines by N—O bond formation. In another aspect, the method can successfully be employed using a wide variety of commercially available alcohols and secondary amines and enables the construction of large fragment-based libraries of trisubstituted hydroxylamines for drug discovery purposes. Also disclosed are N,N,O-trisubstituted hydroxylamines having low basicity, high stability at ambient temperatures, and an inherent lack of reactivity towards acetylating and sulfonylating enzymes that confer mutagenicity on less-substituted hydroxylamines.

专利号:US-3978093-A
优先权日:1971-06-29
标 题:Synthesis of hydroxycyclopenten-1-ones
发明人：BUCHI GEORGE
权利人:HOFFMANN LA ROCHE
摘要:This invention relates to a process for the preparation of 2-alkenyl-4-hydroxy-3-methyl-2-cyclopenten-1-ones from the reaction product of 2,4-pentane dione and a 2-propen-or 2-propyn-1-ol derivative including intermediates therein.

专利号:US-4071542-A
优先权日:1976-04-28
标 题 :Synthesis of hydroxycyclopenten-1-ones
发明人：BUCHI GEORGE
权利人:HOFFMANN LA ROCHE
摘要:This invention relates to a process for the preparation of 2-alkenyl-4-hydroxy-3-methyl-2-cyclopenten-1-ones from the reaction product of 2,4-pentane dione and a 2-propen- or 2-propyn-1-ol derivative including intermediates therein.

专利号:US-5637757-A
优先权日:1995-04-11
标 题 :One-pot synthesis of ring-brominated benzoate compounds
发明人：HILL JOHN E; FAVSTRITSKY NICOLAI A; MAMUZIC RASTKO I; BHATTACHARYA BHABATOSH
权利人:GREAT LAKES CHEMICAL CORP
摘要:A method of preparing tetrabromobenzoate compounds from tetrabromophthalic anhydride by reacting tetrabromophthalic anhydride with alcohol in the presence of a decarboxylation catalyst. The reaction may be carried out in an excess of alcohol, or with a near stoichiometric amount of alcohol by performing the reaction in an inert solvent.

专利号:US-2004053999-A1
优先权日:1997-09-17
标题 :Novel compounds and methods for synthesis and therapy
发明人：BISCHOFBERGER NORBERT W; DAHL TERRENCE C; HITCHCOCK MICHAEL J M; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; MILLS ROGER G; WILLIAMS MATTHEW A
摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.

专利号:US-6225341-B1
优先权日:1995-02-27
标 题:Compounds and methods for synthesis and therapy
发明人：BISCHOFBERGER NORBERT W; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; WILLIAMS MATTHEW A
权利人:GILEAD SCIENCES INC
摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.