CAS: 515-25-3; Betonicine
该化合物是典型的藻类结构特征,通常包括杂环框架内的氮原子.乙酮有其潜在的药理特性,包括抗炎和止痛效应,尽管其具体的行动和治疗应用机制仍在调查之中.该物质通常以晶体形式出现,并可能表现出各种有机溶剂中的溶性.其生物活动引起了对草药和植物化学学的兴趣,促进了对其功效和安全的研究.与许多藻类一样,乙酮的效应可能因剂量和个人反应而不同,因此需要仔细考虑其使用.
- 英文名称Betonicine
- 中文名称左旋水苏碱
- IUPAC名称(2S,4R)-4-hydroxy-1,1-dimethylpyrrolidin-1-ium-2-carboxylate
- 其它别名Trans-2-Carboxy-4-Hydroxy-1,1-Dimethylpyrrolidinium Hydroxide, Inner Salt; (2S,4R)-4-Hydroxy-2-Carboxylato-1,1-Dimethylpyrrolidin-1-Ium; 4-Hydroxy-1,1-Dimethylpyrrolidinium-2-Carboxylate; 4-Hydroxy-Stachydrine; Pyrrolidinium, 2-Carboxy-4-Hydroxy-1,1-Dimethyl-, Inner Salt, (2S,4S)-
- CAS编号515-25-3
- MFCD编号:MFCD00063554
- EINECS号:208-195-6
- FDA UNII编号:FBA654632Q
- 分子式:C7H13NO3分子量:159.18
- 产品CID: 1505038
- 产品分类天然产物 → 生物碱
物理性质
- 熔点246-248°C
- 沸点284.67°C (粗估)
- 闪点 °C
- 密度1.2013 (粗估)
- PH:D20 -34.2° (c = 1.0)
- PSA:60.36
- LogP:-4.240 (est)
- 折射率1.4760 (估算)
- 外观形态固体-粉末
- 储存条件Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
- 产品应用在草药,香料和豆类中可以找到乙酸,这使乙酸成为食用这些食品的潜在生物标志.乙酸主要在尿液中找到.该化合物属于被称为I-ALPHA-AMINO酸的有机化合物类别.
MSDS等安全信息
上下游产品
4-hydroxyproline methyl iodide diazomethane 4R-4-hydroxyproline合成工艺路线路线简述
- 合成目标产物 Betonicine 主要起始原料 L-Hydroxyproline
- (文献来源)合成步骤主要原料 L-Hydroxyproline
海关参考信息
- 2905122000-异丙醇
2905399002-1,4-丁二醇
2912110000-甲醛
2912120000-乙醛 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-11612556-B2
优先权日:2014-12-16
标 题:Peptidic compounds, compositions comprising them and uses of said compounds, in particular cosmetic uses
发明人：PESCHARD OLIVIER; DOUCET ANNE; LEROUX RICHARD; MONDON PHILIPPE
权利人:SEDERMA SA
摘要:The peptidic compound comprises at least an aminoacid which is lysine, ornithine, diaminopropionic acid or diaminobutyric acid or a derivative of these aminoacids, on which a carboxylic acid is grafted via a peptidic bound on the nitrogen of the lateral chain, said carboxylic acid comprising a (poly)cycle or (poly)heterocycle. Preferably, the grafted carboxylic acid is an aminoacid or a derivative, in particular selected from, a proline, a hydroxyproline or pyroglutamic acid.The peptidic compound can stimulate the synthesis of the main molecules constituting the extracellular matrix of the skin, especially collagen 1 and 4 and elastin. It can be used for topical cosmetic treatment such as a global anti-aging treatment, or for specific activities, including anti-wrinkles, moisturizing, to improve the mechanical properties of the skin, firmness/tone/elasticity/flexibility, to increase density and volume of the skin, improve skin radiance, for a restructuring effect and/or to fight stretch marks.
专利号:WO-2007107319-A1
优先权日:2006-03-17
标题:Isolation, structure determination, synthesis and bioactivity of damipipecolin and damituricin
发明人：AIELLO ANNA; GIORDANO ANTONELLA; FATTORUSSO ERNESTO; MENNA MARIALUISA; SCHROEDER HEINZ C; MUELLER WERNER E G
权利人:BIOTECMARIN GMBH; AIELLO ANNA; GIORDANO ANTONELLA; FATTORUSSO ERNESTO; MENNA MARIALUISA; SCHROEDER HEINZ C; MUELLER WERNER E G
摘要:Two new bromopyrrole alkaloids, compounds (1) and (2), have been isolated from the Mediterranean sponge Axinella damicÏ…rnis, and their structure established through spectroscopic methods. Compounds (1) and (2 )display a modulating effect of the serotonin receptor activity and neuroprotective activity in vitro.
专利号:CN-1299419-A
优先权日:1998-03-13
标题:Compositions and method for enhanced synthesis of nucleic acid molecules
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Bashir A, Hoffmann T, Kempf B, Xie X, Smits SHJ, Bremer E. Plant-derived compatible solutes proline betaine and betonicine confer enhanced osmotic and temperature stress tolerance to Bacillus subtilis. Microbiology (Reading). 2014 Oct;160(Pt 10):2283-2294. doi: 10.1099/mic.0.079665-0. Epub 2014 Jul 10. 59(17):9410-6. doi: 10.1021/jf2014815. Epub 2011 Aug 12. 103(2):333-346. doi: 10.1111/mmi.13561. Epub 2016 Nov 11. 23(18):10933. doi: 10.3390/ijms231810933.
5: Ares AM, Martín MT, Tapia JA, González-Porto AV, Higes M, Martín-Hernández R, Bernal J. Differentiation of bee pollen samples according to the betaines and other quaternary ammonium related compounds content by using a canonical discriminant analysis. Food Res Int. 2022 Oct;160:111698. doi: 10.1016/j.foodres.2022.111698. Epub 2022 Jul 20. 28(7):2964. doi: 10.3390/molecules28072964.
7: Ahmed AF, Dai CF, Kuo YH, Sheu JH. The Invasive Anemone Condylactis sp. of the Coral Reef as a Source of Sulfur- and Nitrogen-Containing Metabolites and Cytotoxic 5,8-Epidioxy Steroids. Metabolites. 2023 Mar 7;13(3):392. doi: 10.3390/metabo13030392.
合成参考文献
参考文献:10.2116/analsci.17.103
摘要:Nishimura N, Zhang J, Abo M, Okubo A, Yamazaki S. Application of capillary electrophoresis to the simultaneous determination of betaines in plants. Anal Sci. 2001 Jan;17(1):103–6. doi: 10.2116/analsci.17.103.
参考文献:10.1038/ncb3255
摘要:Lin R, Elf S, Shan C, Kang HB, Ji Q, Zhou L, Hitosugi T, Zhang L, Zhang S, Seo JH, Xie J, Tucker M, Gu TL, Sudderth J, Jiang L, Mitsche M, DeBerardinis RJ, Wu S, Li Y, Mao H, Chen PR, Wang D, Chen GZ, Hurwitz SJ, Lonial S, Arellano ML, Khoury HJ, Khuri FR, Lee BH, Lei Q, Brat DJ, Ye K, Boggon TJ, He C, Kang S, Fan J, Chen J. 6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling. Nat Cell Biol. 2015 Nov;17(11):1484–96.
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