专利号:US-8445715-B2 优先权日:2007-07-02 标 题 :Method of synthesizing fenofibrate 发明人:LUCAS BEATRICE 权利人:LUCAS BEATRICE; SYNKEM 摘要:A novel process for the synthesis of fenofibrate, includes reacting a metal salt of fenofibric acid with an isopropyl halide, in a solvent system composed of a mixture of dimethyl sulfoxide and a C 2 -C 4 alkyl acetate. The process can be used on an industrial scale and makes it possible to obtain a fenofibrate of a quality in accordance with the Pharmacopoeia without the need for purification by recrystallization.
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专利号:JP-5442603-B2 优先权日:2007-07-02 标 题:A new synthesis of fenofibrate
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