CAS: 42719-32-4; (2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-Yl (1R,2R,4As,6As,6Br,8Ar,9R,10S,12Ar,12Br,14Bs)-1,10-Dihydroxy-9-(Hydroxymethyl)-1,2,6A,6B,9,12A-Hexamethyl-1,3,4,5,6,6A,6B,7,8,8A,9,10,11,12,12A,12B,13,14B-Octadecahydropicene-4A(2
该化合物是源于自然来源的生物活性胶质化合物,以其潜在的药理应用而著称,它具有显著的结构特性,其特点是独特的糖碱和甘蔗成分,有助于其生物活动.研究表明, Peduncloside II可能拥有抗炎,抗氧化剂或...
- 英文名称(2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-Yl (1R,2R,4As,6As,6Br,8Ar,9R,10S,12Ar,12Br,14Bs)-1,10-Dihydroxy-9-(Hydroxymethyl)-1,2,6A,6B,9,12A-Hexamethyl-1,3,4,5,6,6A,6B,7,8,8A,9,10,11,12,12A,12B,13,14B-Octadecahydropicene-4A(2
- 中文名称具栖冬青苷
- IUPAC名称(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl (1R,2R,4aS,6aS,6bR,8aR,9R,10S,12aR,12bR,14bS)-1,10-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicene-4a(2H)-carboxylate
- 其它别名(2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-Yl (1R,2R,4As,6As,6Br,8Ar,9R,10S,12Ar,12Br,14Bs)-1,10-Dihydroxy-9-(Hydroxymethyl)-1,2,6A,6B,9,12A-Hexamethyl-1,3,4,5,6,6A,6B,7,8,8A,9,10,11,12,12A,12B,13,14B-Octadeca
- CAS编号42719-32-4
- MFCD编号:MFCD01632712
- 分子式:C36H58O10分子量:650.85
- 产品CID: 1439526
- 产品分类生物化工 → 中草药成分
物理性质
合成工艺路线路线简述
📜Ilexoside Xxxiv置于吡啶体系中,用 1,4-二氧六环 作为反应溶剂,化学反应 5.0H,以12 Mg的收率获得产物具栖冬青苷
参考文献:圆叶冬青叶中的三萜和三萜糖苷
标题:圆叶冬青叶中的三萜和三萜糖苷
摘要:摘要 从圆叶冬青的新鲜叶片中分离出两种新的三萜类异黄酮酸 A 和 B 和七种新的皂苷 Xxxiii-Xxxix 以及已知的皂苷罗通皂苷,并根据化学和物理化学证据阐明了它们的结构. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Ilexolic Acid A 和 B 的结构分别被阐明为 3β,19α,21β,23-Tetrahydroxyurs-12-En-28-Oic Acid 和 3β,19α-Dihydroxyolean-12-Ene-18,23-Dioic Acid.ilexoside Xxxiii 是 23-Oxosiaresinolic Acid 的 3-O-葡糖苷酸,Ilexoside Xxxiv 是 Pedunculoside
DOI:10.1016/0031-9422(93)85114-7
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Zhao W, Pang L, Xu D, Zhang N. LC-MS/MS Determination and Pharmacokinetic Study of Pedunculoside in Rat Plasma after Oral Administration of Pedunculoside and Ilex rotunda Extract. Molecules. 2015 May 19;20(5):9084-98. doi: 10.3390/molecules20059084.
2: Liu C, Shen YJ, Tu QB, Zhao YR, Guo H, Wang J, Zhang L, Shi HW, Sun Y. Pedunculoside, a novel triterpene saponin extracted from Ilex rotunda, ameliorates high-fat diet induced hyperlipidemia in rats. Biomed Pharmacother. 2018 May;101:608-616. doi: 10.1016/j.biopha.2018.02.131. Epub 2018 Mar 22. doi: 10.1371/journal.pone.0101761. eCollection 2014.
4: Wang C, Chao Z, Sun W, Wu X, Ito Y. Enrichment and purification of pedunculoside and syringin from the barks of Ilex rotunda with macroporous resins. J Liq Chromatogr Relat Technol. 2014 Feb 1;37(4):572-587.
合成参考文献
参考文献:10.1016/s0031-9422(00)97768-9
摘要:Nakatani M, Miyazaki Y, Iwashita T, Naoki H, Hase T. Triterpenes from Ilex rotunda fruits. Phytochemistry. 1989;28(5):1479–82. doi: 10.1016/s0031-9422(00)97768-9.
参考文献:10.1021/np50123a012
摘要:Heinzmann BM, Schenkel EP. Saponins from Ilex dumosa. J. Nat. Prod. 1995 Sep;58(9):1419–22. doi: 10.1021/np50123a012.
参考文献:10.1016/j.fitote.2018.07.005
摘要:Yang B, Li H, Ruan Q, Tong Y, Liu Z, Xuan S, Jin J, Zhao Z. Rapid profiling and pharmacokinetic studies of multiple potential bioactive triterpenoids in rat plasma using UPLC/Q-TOF-MS/MS after oral administration of Ilicis Rotundae Cortex extract. Fitoterapia. 2018 Sep;129():210–9. doi: 10.1016/j.fitote.2018.07.005.
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