CAS: 303-69-5; N,N-Dimethyl-3-Pyrido[3,2-B][1,4]Benzothiazin-10-Ylpropan-1-Amine
该化合物是一种主要用于兽医,特别是其镇静剂和抗乳性能的抗口炎和抗胆碱酯酶剂,属于二苯乙烷的化合物类别,其特点是能够阻塞丙胺H1受体,这有助于减轻过敏反应和运动疾病.丙烯基通常以盐盐的形式施用,提高其溶解性和生物利用率.该物质在按指示使用时表现出相对较低的毒性特征,但谨慎从事,因为具有潜在的副作用,如镇静剂,干嘴和尿液保留.其药理效应可归因于其跨越血液-脑屏障的能力,导致...
- 英文名称N,N-Dimethyl-3-Pyrido[3,2-B][1,4]Benzothiazin-10-Ylpropan-1-Amine
- 中文名称丙硫喷地
- IUPAC名称10H-Pyrido(3,2-b)(1,4)benzothiazine, 10-(3-(dimethylamino)propyl)-
- 其它别名10H-Pyrido[3,2-b][1,4]benzothiazine,10-[3-(dimethylamino)propyl]- (6CI,8CI); 10-(3-Dimethylaminopropyl)-10H-pyrido[3,2-b][1,4]benzothiazine; 2,3-Pyridino-(5',6')-5,6-benzo-4-(3''-dimethylaminopropyl)-1,4-thiazine; Dominal; Largophren; Phrenotropin; Prothipendyl; Timoval; Timovan; Tumovan
- CAS编号303-69-5
- MFCD编号:MFCD00867993
- EINECS号:608-469-9
- FDA UNII编号:5O6VWA87VA
- 分子式:C16H19N3S分子量:285.413
- 产品CID: 1288336
- 产品分类有机原料 → 有机氮化合物
物理性质
MSDS等安全信息
欧盟法规
REACH注册ECHA物质C&L通报REACH预注册上下游产品
CAS号261-96-1 氮杂苯酚噻嗪 | CAS号109-54-6 3-氯-1-(N,N-二甲基)丙胺 | CAS号92316-06-8 2-[(3-硝基-2-吡啶)磺酰基]苯胺 | CAS号91902-18-0 N-[2-(3-nitropy... | CAS号137-07-5 2-氨基苯硫酚 | CAS号6631-37-4 2-苯基氨基吡啶 | CAS号124-40-3 二甲胺 | CAS号109-70-6 1-溴-3-氯丙烷合成工艺路线路线简述
📜2-苯胺基吡啶置于碘,Sulfur,Sodium Amide体系中,化学反应生成 丙硫喷地
参考文献:Schuler,W.A.; Klebe,H.,Justus Liebigs Annalen Der Chemie,1962,Vol. 653,P. 172-180
标题:Schuler,W.A.; Klebe,H.,Justus Liebigs Annalen Der Chemie,1962,Vol. 653,P. 172-180
海关参考信息
- 2933310010-吡啶
2930909099-其他有机硫化合物
2939800000-其他生物碱 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:WO-2025118034-A1
优先权日:2023-12-06
标题 :Compounds active at the serotonergic 5-ht2a receptor
发明人：JORGENSON WILLIAM; TAN JINLONG; WHISH LACHLAN; BANISTER SAMUEL
权利人:Psylo Pty Ltd
摘要:The present disclosure relates to compounds of formula (I), their methods of synthesis, and their use in the treatment of mental illness or central nervous system disorders.
专利号:WO-2023230649-A1
优先权日:2022-05-30
标题:Compounds
发明人：BANISTER SAMUEL; JORGENSEN WILLIAM; TAN JINLONG; WHISH LACHLAN
权利人:Psylo Pty Ltd
摘要:The present disclosure relates to compounds of formula (I), their methods of synthesis, and their use in the treatment of mental illness or central nervous system disorders.
专利号:US-12415804-B2
优先权日:2023-06-28
标题 :Compounds for activating a serotonin receptor
发明人：BANISTER SAMUEL; JORGENSEN WILLIAM; TAN JINLONG; WHISH LACHLAN
权利人:Psylo Pty Ltd
摘要:The present disclosure relates generally to compounds, their methods of synthesis, and their use in the treatment of mental illness or central nervous system disorders.
专利号:US-12428380-B2
优先权日:2023-06-28
标 题 :Compounds
发明人：BANISTER SAMUEL; JORGENSEN WILLIAM; TAN JINLONG; WHISH LACHLAN
权利人:Psylo Pty Ltd
摘要:The present disclosure relates generally to compounds, their methods of synthesis, and their use in the treatment of mental illness or central nervous system disorders.
专利号:US-2025101038-A1
优先权日:2021-12-24
标 题 :Compounds
发明人：BANISTER SAMUEL; JORGENSEN WILLIAM; TAN JINLONG
权利人:Psylo Pty Ltd
摘要:The present disclosure relates generally to compounds, their methods of synthesis, and their use in the treatment of mental illness or central nervous system disorders.
专利号:US-2025163044-A1
优先权日:2021-12-24
标 题:Compounds
发明人：BANISTER SAMUEL; JORGENSEN WILLAM; TAN JINLONG
权利人:Psylo Pty Ltd
摘要:The present disclosure relates generally to compounds, their methods of synthesis, and their use in the treatment of mental illness or central nervous system disorders.
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Caspar AT, Meyer MR, Maurer HH. Blood plasma level determination using an automated LC-MS(n) screening system and electronically stored calibrations exemplified for 22 drugs and two active metabolites often requested in emergency toxicology. Drug Test Anal. 2018 Jul 16. doi: 10.1002/dta.2466. [Epub ahead of print] doi: 10.1002/dta.2319. Epub 2017 Nov 13. doi: 10.1016/j.jpba.2017.07.011. Epub 2017 Jul 12. doi: 10.1016/j.pnpbp.2017.03.002. Epub 2017 Mar 14. Epub 2016 Aug 4.
6: Wahl M, Tipotsch-Maca SM, Vecsei-Marlovits PV. Intraoperative floppy iris syndrome and its association with various concurrent medications, bulbus length, patient age and gender. Graefes Arch Clin Exp Ophthalmol. 2017 Jan;255(1):113-118. doi: 10.1007/s00417-016-3515-7. Epub 2016 Oct 19. doi: 10.1016/j.euroneuro.2016.07.006. Epub 2016 Jul 27. doi: 10.1007/5584_2015_183. doi: 10.2116/analsci.31.961. Review. German. doi: 10.1007/s40211-014-0097-7. Epub 2014 Feb 7. German. doi: 10.1002/14651858.CD007726.pub2. Review. doi: 10.1007/s00508-013-0342-2. Epub 2013 Mar 28. Review.
合成参考文献
参考文献:10.1007/s00216-011-5187-9
摘要:Remane D, Meyer MR, Wissenbach DK, Maurer HH. Ultra high performance liquid chromatographic-tandem mass spectrometric multi-analyte procedure for target screening and quantification in human blood plasma: validation and application for 31 neuroleptics, 28 benzodiazepines, and Z-drugs. Analytical and Bioanalytical Chemistry. 2011 Jul 21;401(4):1341. doi: 10.1007/s00216-011-5187-9.
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