CAS: 21543-49-7; 2-Chloro-5-Hydroxymethylpyridine

相似化合物

23100-12-1 49608-01-7 5326-23-8

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CAS号73781-91-6 6-氯烟酸甲酯 | CAS号49608-01-7 6-氯烟酸乙酯 | CAS号5326-23-8 6-氯烟酸 | CAS号70258-18-3 2-氯-5-氯甲基吡啶 | CAS号5006-66-6 6-羟基烟酸 | CAS号58757-38-3 6-氯吡啶-3-羰酰氯 | CAS号1603-41-4 2-氨基-5-甲基吡啶 | CAS号3510-66-5 2-溴-5-甲基吡啶 | CAS号85320-79-2 5-氯烟酰氯 | CAS号234109-28-5 2-((6-氯吡啶-3-基)氧基)乙酸 | CAS号39891-09-3 2-氯-5-吡啶乙腈 | CAS号221146-31-2 1-(6-氯-3-嘧啶)-N,... | CAS号1322622-11-6 2-N,N-dimethyla... | CAS号748796-38-5 (6-(1H-吡唑-1-基)吡... | CAS号70258-18-3 2-氯-5-氯甲基吡啶 | CAS号73781-91-6 6-氯烟酸甲酯 | CAS号132951-11-2 2-chloro-5-(oxa... | CAS号159153-42-1 2-chloro-5-(2-n... | CAS号101990-45-8 2-溴-5-(溴甲基)吡啶 | CAS号159153-39-6 3-(6-氯代-吡啶-3-基)...

6-溴烟酸置于sodium Tetrahydroborate,三氯氧磷体系中,化学反应生成2-氯-5-羟甲基吡啶
参考文献:Substituted Dipyridylethenes And-Ethynes And Key Pyridine Building Blocks
标题:Substituted Dipyridylethenes And-Ethynes And Key Pyridine Building Blocks
摘要:合成了多种新的2,5-二取代吡啶.通过还原烟酸3,氨基二甲基吡啶6的水解或5-溴吡啶12和14与丁基锂在dmf中的反应,得到了2-取代的5-醛基吡啶8,15A-B.双吡啶乙烯16A-B,E通过wadsworth-Emmons反应与吡啶基膦酸酯7合成,或者通过mcmurry反应将醛偶联形成烯烃16C-D.在双吡啶乙烯16A-D的c=c双键溴化后,经过1,2-双吡啶-1,2-二溴乙烷17A-D的消除,得到了双吡啶乙炔18A-D.
Doi:10.1055/s-1994-25411

专利信息

专利号:US-7919627-B2
优先权日:2005-05-02
标题:Processes for the preparation of hydroxylamines
发明人：TANG DATONG; QIU YAO-LING; KIM HEEJIN; OR YAT SUN; WANG ZHE
权利人:ENANTA PHARM INC
摘要:The present invention relates generally to novel methods for the synthesis of O-(6-pyrazol-1-yl-pyridin-3-ylmethyl)-hydroxylamine which is an essential reagent in the synthesis of one of the bridged erythromycin derivatives and their respective pharmaceutically acceptable salts in PCT Application WO 03/097659 A1. In particular, the present invention relates to processes and intermediates for the preparation of a compound of formula (Ia):

专利号:US-4285969-A
优先权日:1979-03-09
标 题:Pyrethroids
发明人：GALLI REMO; GOZZO FRANCO; PALLA OTTORINO; LONGONI ANGELO
权利人:MONTEDISON SPA
摘要:The present invention concerns new pyrethroids having a high insecticidal activity. More particularly, this invention relates to novel esters of 2,2-dimethyl-cyclopropanecarboxylic acids substituted in the 3 position; the preparation of said novel esters; the use of said novel esters as insecticides and to insecticidal compositions containing said novel esters as the active ingredient. The present invention also includes providing intermediates for the synthesis of the new pyrethroids and the process for the preparation of said intermediates.

专利号:WO-2016097345-A1
优先权日:2014-12-19
标题 :Labelled chromone derivatives
发明人：JACKSON ALEXANDER
权利人:GE HEALTHCARE LTD
摘要:The present invention relates to compounds having selective binding for MAO-B as compared with MAO-A. The invention also provides radioactive versions of these compounds, and precursor compounds for the synthesis of these radioactive compounds. The radioactive compounds of the invention are particularly useful for in vivo imaging applications.

专利号:US-2007275968-A1
优先权日:2004-09-07
标 题 :Substituted Biphenyl Derivative
发明人：KURATA HITOSHI; NISHIMATA TOYOKI; WATANABE YUKIKO; EBISAWA MASAYUKI; FUJIMOTO TEPPEI; KOBAYASHI HIDEKI
权利人:KURATA HITOSHI; NISHIMATA TOYOKI; WATANABE YUKIKO; EBISAWA MASAYUKI; FUJIMOTO TEPPEI; KOBAYASHI HIDEKI
摘要:The present invention relates to a biaryl derivative or a pharmacologically acceptable salt thereof having an excellent collagen-synthesis inhibition activity. A biaryl derivative having a structure represented by the following General Formula (I) or a pharmacologically acceptable salt thereof: n nwherein n R 1 represents a C 6 -C 10 aryl group which is substituted with one to three group(s) each independently selected from the group consisting of a group defined by formula R-L-, a di-(C 1 -C 6 alkyl)amino group, a di-(C 1 -C 6 alkyl)aminosulfonyl group, a hydroxyaminocarbonyl group, and a halogen atom, and so on; R represents a C 1 -C 6 alkyl group, and so on; L represents a sulfonyl group, an aminosulfonyl group, or a sulfonylamino group, and so on; R 2 represents a hydrogen atom, and so on; A represents a group defined by formula (II), (III), or (IV); R 3 represents a C 1 -C 6 alkyl group, and so on; and R 4 represents a C 1 -C 6 alkyl group, and so on.

专利号:CN-108689919-A
优先权日:2018-05-24
标 题:Continuous Synthesis Process of 2-Chloro-5-Chloromethylpyridine