CAS: 1672-50-0; 4,5-Diamino-6-Hydroxypyrimidine

相似化合物

1004-76-8 69785-94-0 52502-66-6

上下游产品

CAS号1004-76-8 2-巯基-4-羟基-5,6-二氨基嘧啶 | CAS号36746-26-6 6-amino-5-nitro... | CAS号4316-98-7 6-氯嘧啶-4,5-二胺 | CAS号2846-89-1 4,5-二氨基-6-巯基嘧啶 | CAS号69816-38-2 2-氨基-5-三氟甲基吡嗪 | CAS号64194-58-7 6-氨基-5-甲氨基-3H-嘧啶-4-酮 | CAS号13231-00-0 7H-嘌呤-6,8-二醇 | CAS号34244-80-9 7-Methyl-4(1H)-... | CAS号7598-41-6 [1,2,5]噻二唑并[3,4... | CAS号7698-94-4 [1,2,5]Selenadi... | CAS号50609-15-9 N-(6-amino-4-ox...

4,5-Diamino-6-Hydroxypyrimidine Sulphate置于polymer-Supported Carbonate体系中,用 N,N-二甲基甲酰胺,乙腈 用作溶剂,化学反应 24.0H,反应生成4,5-二氨基-6-羟基嘧啶
参考文献:Wo2007/71966
标题:Wo2007/71966

专利信息

专利号:US-7060818-B2
优先权日:2003-02-21
标题:Synthesis of macrocyclic tetraamido compounds and new metal insertion process
发明人：HORWITZ COLIN P; GHOSH ANINDYA
权利人:UNIV CARNEGIE MELLON
摘要:An improved method of synthesizing a macrocyclic tetraamido compound includes protecting the amino portion of an amino carboxylic acid to form a protected amino carboxylic acid; exposing the protected amino carboxylic acid to a first solvent, preferably a hydrocarbon solvent, such as toluene or 1,2-dichloroethane, dichloromethane, dibromomethane and 1,2-dibromoethane. The carboxylic acid portion of the protected amino carboxylic acid is then converted to an activated carboxylic acid by one of esterification or acid halide formation, to form a protected amino activated carboxylic acid derivative. The protected amino activated carboxylic acid derivative is reacted with a diamine in the presence of a second solvent, such as THF or ,2-dichloroethane, dichloromethane, dibromomethane and 1,2-dibromoethane, to form a protected diamide diamine intermediate. Following deprotection, the diamide diamine intermediate is reacted with an activated diacid, such as an activated malonate, oxalate or succinate derivative to form the macrocyclic tetraamido compound. The macrocyclic tetraamido compound may further be complexed with a transition metal.

专利号:US-6153615-A
优先权日:1991-12-26
标 题 :Blocking induction of tetrahydrobioterin to block induction of nitric oxide synthesis
发明人：GROSS STEVEN S
权利人:CORNELL RES FOUNDATION INC
摘要:Guanosine triphosphate pathway tetrahydrobiopterin synthesis antagonist and/or pterin salvage pathway tetrahydrobiopterin synthesis antagonists are administered to inhibit nitric oxide synthesis from arginine in vascular cells in a subject in need of such inhibition (e.g., for prophylactic or curative effect for endotoxin- or cytokine-induced hypotension or for restoration of vascular contractile sensitivity to pressor agents in the treatment of such hypotension). The tetrahydrobiopterin synthesis antagonist may be administered with α 1 -adrenergic agonist or with nitric oxide synthase inhibitor. The tetrahydrobiopterin synthesis antagonists are also administered to attenuate inflammation caused by induced nitric oxide production in immune cells. Unwanted counterproductive or side effects can be eliminated or ameliorated by administration additionally of levodopa with or without carbidopa and L-5-hydroxytryptophane.

专利号:US-6274581-B1
优先权日:1991-12-26
标 题 :Blocking induction of tetrahydrobiopterin to block induction of nitric oxide synthesis
发明人：GROSS STEVEN S
权利人:CORNELL RES FOUNDATION INC
摘要:Guanosine triphosphate pathway tetrahydrobiopterin synthesis antagonist and/or pterin salvage pathway tetrahydrobiopterin synthesis antagonist are administered to inhibit nitric oxide synthesis from arginine in vascular smooth muscle cells in a subject in need of such inhibition (e.g. for prophylactic or curative effect for cytokine-induced hypotension or for restoration of vascular contractile sensitivity to pressor agents in the treatment of such hypotension).

专利号:US-7888506-B2
优先权日:2007-01-26
标 题 :Composition, synthesis, and use of a new class of fluorophores
发明人：BASU PARTHA; SERLI MITASEV BARBARA
权利人:UNIV HOLY GHOST DUQUESNE
摘要:A new class of fluorophores is presented. The fluorophores include a conjugated ring system, such as a dithiolone, a pyran, and a pyrazine containing ring system. The structure is designed with the flexibility to have multiple substitution patterns. The fluorophores may be used in applications including, but not limited to, biomarker applications, pH sensors, metal sensors, and as components for molecular electronics.

专利号:WO-2004076425-A1
优先权日:2003-02-21
标题:Improved synthesis of macrocyclic tetraamido compounds and new metal insertion process

专利号:US-5877176-A
优先权日:1991-12-26
标题 :Blocking induction of tetrahydrobiopterin to block induction of nitric oxide synthesis