专利号:US-7662401-B2 优先权日:2002-04-08 标 题 :Administration of extracts of nonfruiting nonphotosynthetic filamentous bacteria for increasing the endogenous synthesis of superoxide dismutase 发明人:MAHE YANN; MEYBECK ALAIN 权利人:OREAL 摘要:The present invention relates to the cosmetic or pharmaceutical use of an extract of a nonfruiting nonphotosynthetic filamentous bacterium in a composition containing a cosmetically or pharmaceutically acceptable medium, as an agent increasing the endogenous synthesis of superoxide dismutase, in particular for preventing and/or limiting the formation of free radicals and/or removing the free radicals present in cells; in addition, the invention relates to a composition comprising at least one extract of Vitreoscilla filiformis and lycopene.
专利号:US-2012003164-A1 优先权日:1998-12-30 标题 :Cosmetic or dermatological composition containing an active agent which stimulates synthesis of the protein hsp 32 in the skin 发明人:NIZARD CARINE; MOREAU MARIELLE; BONTE FREDERIC 权利人:NIZARD CARINE; MOREAU MARIELLE; BONTE FREDERIC; DIOR CHRISTIAN PARFUMS 摘要:A dermatological or cosmetological composition for an external topical administration, included together with pharmaceutically and/or cosmetologically acceptable excipients: at least one UVA-stabilizing and/or UVB-stabilizing screening agent, at least one compound capable of activating the endogenous synthesis of Heat Shock Protein (HSP) 32 or a functional peptide fragment of such a protein, and forskolin or any extract containing it.
专利号:US-9579267-B2 优先权日:2011-07-14 标 题:Cosmetic with enhanced collagen I synthesis 发明人:DOUCET OLIVIER; BERNINI DOROTHEE; ROBERT CECILE; PUJOS MURIEL 权利人:DOUCET OLIVIER; BERNINI DOROTHEE; ROBERT CECILE; PUJOS MURIEL; COTY GERMANY GMBH 摘要:A cosmetic including two different systems for procurement of actives in the human skin and enhancing the collagen I synthesis. The cosmetic with enhanced collagen I synthesis can include 0.001 to 2% by weight, related to the total weight of the cosmetic, of a first retinol-containing system including retinol encapsulated in a chitosan and carboxymethyl cellulose shell, 0.001 to 3.5% by weight, related to the total weight of the cosmetic, of a second retinol-containing system including cationic liposomes composed of phospholipids and with a quaternary fatty acid monoamine with C 21 -C 23 alkyl residue and the difference to 100% by weight of cosmetic subsidiaries. Very small amounts of retinol in combination with both transport systems show a remarkable effect on the synthesis of collagen I in comparison with one or more other known combinations of retinol derivatives or encapsulated systems.
专利号:US-10799441-B2 优先权日:2011-06-06 标题:Skin treatments containing pyrroloquinoline quinone (PQQ) esters and methods of preparation and use thereof 发明人:LEWIS II JOSEPH ABERNATHY; DINARDO JOSEPH C 权利人:LEWIS II JOSEPH ABERNATHY; DINARDO JOSEPH C; PCR TECH HOLDINGS LC 摘要:The present invention relates to cosmetic or dermatological compositions containing PQQ or its esters, methods of treating or promoting skin changes by topical application of these compositions, and methods of synthesis of PQQ esters. The PQQ ester-containing compositions of the present invention are unexpectedly effective in treating skin, particularly with respect to skin tolerance. When included in a topical composition, the PQQ esters of the present invention have an antioxidant effect that is useful in treating a skin change.
专利号:EP-1354593-B1 优先权日:2002-04-08 标题 :use of an extract of a non-photosynthetic filamentous bacterium as an agent for enhancing the endogenous synthesis of superoxide dismutase 发明人:MAHE YANN; MEYBECK ALAIN 权利人:OREAL 摘要:Promoting endogenous production of superoxide dismutase (SOD) comprises the use of an extract (I) of non-photosynthetic, non-fruiting filamentous bacteria in cosmetic, dermatological or pharmaceutical applications. Use of an extract (I) of non-photosynthetic, non-fruiting filamentous bacteria: (1) in a composition based on a cosmetic medium, as an agent for promoting endogenous production of superoxide dismutase (SOD); or (2) for production of a pharmaceutical or dermatological composition for promoting endogenous production of SOD. Independent claim are also included for: (1) a composition comprising a physiological medium containing Vitreoscilla filliformis extract (Ia) and lycopene (specifically at 0.000000001-0.1 wt. %) or a compound having catalase activity and/or a compound having peroxidase activity; and (2) cosmetic treatment methods for treating loss of firmness and/or elasticity of the skin or for treating skin exposed to sunlight, involving application of compositions containing (Ia).
专利号:US-9572768-B2 优先权日:2011-04-20 标 题:Cosmetic composition for use in increasing the collagen synthesis in skin cells 发明人:DOUCET OLIVIER; PUJOS MURIEL; ROBERT CÉCILE; BERNINI DOROTHÉE 权利人:DOUCET OLIVIER; PUJOS MURIEL; ROBERT CÉCILE; BERNINI DOROTHÉE; COTY GERMANY GMBH 摘要:The invention refers to a cosmetic composition for increasing collagen synthesis in skin cells comprising 0.001-0.5 wt % of a Phaeodactylum tricornutum extract, 0.00001-2.0 wt % of Dimer Tripeptide-43 or Hydrolyzed Rice Protein, and cosmetic auxiliaries. The cosmetic composition comprising the combination of both components has an synergistic effect on collagen I synthesis in skin cells and has a booster effect to other substances which are known to have an enhancing effect to collagen I synthesis.