专利号:US-8252928-B2 优先权日:2008-09-16 标题:Processes for the synthesis of five and six membered heterocyclic rings 发明人:WANG PETER X; JIANG TAO; BERBERICH DAVID W 权利人:WANG PETER X; JIANG TAO; BERBERICH DAVID W; MALLINCKRODT LLC 摘要:The present invention provides processes for the synthesis of five and six membered rings. In particular, the present invention provides processes for the synthesis of five and six membered rings in alkaloids.
专利号:US-6455680-B1 优先权日:2000-12-21 标 题 :Methods utilizing aryl thioimines in synthesis of erythromycin derivatives 发明人:LUKIN KIRILL A 权利人:ABBOTT LAB 摘要:An efficient deoximation technique for use in synthesis of erythromycin derivatives, involving aryl thioimine intermediates is disclosed. The aryl thioimine intermediates can be utilized in a method for protecting a ketone of a ketone-containing erythromycin derivative as a thioimine; a method for deoximating an oxime-containing erythromycin derivative, or a method for preparing a 6-O-alkyl erythromycin derivative. Presently preferred erythromycin derivatives have a C-9 oxime or a C-9 ketone.
专利号:JP-2003524567-A 优先权日:1997-08-15 标题:Electrical synthesis of hydroxylammonium salt and hydroxylamine using mediator, catalyst film, method for preparing catalyst film, and electrical synthesis of compound using catalyst film
专利号:ES-2664252-T3 优先权日:2008-09-16 标 题:Processes for the synthesis of five- and six-membered heterocyclic rings
专利号:CA-2737159-C 优先权日:2008-09-16 标 题:Processes for the synthesis of five and six membered heterocyclic rings
专利号:CN-101402567-B 优先权日:2008-11-14 标题 :Method for synthesis of mixed dibasic acid dimethyl ester with sodium bisulfate catalysis
参考文献:10.1016/j.bmcl.2010.01.081 摘要:Innocenti A, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors. Inhibition of transmembrane isoforms IX, XII, and XIV with less investigated anions including trithiocarbonate and dithiocarbamate. Bioorganic & Medicinal Chemistry Letters. 2010 Mar;20(5):1548–50. doi: 10.1016/j.bmcl.2010.01.081.