CAS: 13526-66-4; 3-Bromo-6-Chloroimidazo[1,2-B]Pyridazine

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6-氯咪唑并[1,2-B]哒嗪盐酸盐置于n-溴代丁二酰亚胺(Nbs)体系中,用 乙腈 用作溶剂,化学反应 2.0H,以82%的收率获得3-溴-6-氯咪唑并[1,2-B]哒嗪
参考文献: Aryl Amide Kinase Inhibitors[fr] Inhibiteurs De L'Arylamide Kinase
标题: Aryl Amide Kinase Inhibitors[fr] Inhibiteurs De L'Arylamide Kinase
摘要:本公开涉及一般可抑制aak1(适配器相关激酶1)的化合物,包括这些化合物的组合物,以及抑制aak1的方法.

专利信息

专利号:US-9370515-B2
优先权日:2013-03-07
标题 :Mixed lineage kinase inhibitors and method of treatments
发明人：GOODFELLOW VAL S; NGUYEN THONG X; RAVULA SATHEESH B; GELBARD HARRIS A
权利人:CALIFIA BIO INC; UNIV ROCHESTER
摘要:Provided herein are imidazopyridine compounds having an inhibitory effect on mixed lineage kinases (MLKs), methods of their synthesis, and methods of their therapeutic. Also provided are pharmaceutical compositions comprising the compounds and methods of using the compounds and pharmaceutical compositions.