CAS: 97232-97-8; Cefuroxime

上下游产品

Cefuroxime trans-cefuroxime axetil is°Cyanate de chlorosulfonyle (Z)-2-methoxyimino-2-(furyl-2-yl)acetic acid ammonium saltCefuroxime

头孢呋辛 以 甲醇,水 作为反应溶剂,化学反应生成 去乙基乙酸酯(E)-头孢呋辛酯
参考文献:头孢呋辛酯及相关化合物的光异构化动力学
标题:头孢呋辛酯及相关化合物的光异构化动力学
摘要:用HPLC研究了头孢呋辛酯水溶液在254 Nm下的光致异构化动力学.总体降解是烷氧基亚氨基基团的异构化与β-内酰胺环的光解之间竞争的结果.头孢呋辛酯以两种非对映异构体的混合物形式存在,并显示出不同的反应速率.这不仅适用于光异构化步骤,而且适用于碱性条件下的基态水解.头孢呋辛酯的抗异构体及其某些降解产物也观测到了烷氧基亚氨基的光异构化.所有这些光异构化的量子产率始终低于1%,这说明了光解步骤的相对重要性.头孢呋辛酯的固定顺式与反比为1,头孢呋辛为2.1.从这项研究和以前的研究来看,与其他带有烷氧基亚氨基的抗生素相比,头孢呋辛酯在254 Nm照射下最敏感.氨曲南最稳定,其次是头孢噻肟,头孢呋辛和头孢呋辛酯.
DOI:10.1002/jps.2600830422

专利信息

专利号:US-10925977-B2
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
发明人：YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S
权利人:YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S; CEIL POINT LLC; UNIV TEXAS
摘要:Novel methods of synthesis of chelator-targeting ligand conjugates, compositions comprising such conjugates, and therapeutic and diagnostic applications of such conjugates are disclosed. The compositions include chelator-targeting ligand conjugates optionally chelated to one or more metal ions. Methods of synthesizing these compositions in high purity are also presented. Also disclosed are methods of imaging, treating and diagnosing disease in a subject using these novel compositions, such as methods of imaging a tumor within a subject and methods of diagnosing myocardial ischemia.

专利号:US-2024197774-A1
优先权日:2021-04-16
标 题:Synthesis of Antimicrobial PVP-coated Bismuth Nanoparticles
发明人：LOPEZ-RIBOT JOSE; VAZQUEZ-MUNOZ ROBERTO
权利人:UNIV TEXAS
摘要:Described herein is a facile, fast, and economical method for the synthesis of BAL-mediated PVP-BiNPs, using basic laboratory instruments and reagents readily available in most laboratories.

专利号:US-6777553-B1
优先权日:2003-03-25
标题 :Process for synthesis of bis-(substituted-4-quinolyl) disulphides
发明人：MESHRAM HARSHADAS MITARAM; KOKKU PREMALATHA; AYYAGIRI VENKATA MADHAVI; BEGARI ESHWARAIAH; YADAV JHILLU SINGH
权利人:COUNCIL SCIENT IND RES
摘要:The present invention relates to a process for the synthesis of bis-(substituted-4-quinolyl) disulphides.

专利号:US-2005186197-A1
优先权日:2002-08-29
标 题:Peptide inhibitors of beta lactamases
发明人：PALZKILL TIMOTHY; HUANG WANZHI
摘要:Peptide inhibitors of β-lactamases have been identified by the synthesis of peptide arrays using synthesis SPOT technology. These peptide inhibitors of β-lactamase have activity against a broad spectrum of β-lactamases and are useful in a variety of applications.

专利号:US-8557979-B2
优先权日:2004-06-10
标题 :Carbapenem antibacterials with gram-negative activity and processes for their preparation
发明人：CHOI WOO-BAEG; KOWALIK EWA
权利人:CHOI WOO-BAEG; KOWALIK EWA; FOB SYNTHESIS INC
摘要:The present invention provides β-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment. The present invention is also in the field of synthetic organic chemistry and is specifically provides an improved method of synthesis of β-methyl carbapenems which are useful as antibacterial agents.

专利号:WO-0034289-A1
优先权日:1998-12-08
标 题:Process of preparing esters of penicillanic acid sulfoxide
发明人：GARDNER JOHN PAUL; ZHANG TONY YANTAO
权利人:LILLY CO ELI; GARDNER JOHN PAUL; ZHANG TONY YANTAO
摘要:A new synthesis of penicillanic sulfoxide acid ester is claimed. The synthesis starts with 6-amino penicillanic acid and proceeds through conversion to a bromide via diazotization, esterification, reduction of the bromide, and oxidation of the resulting penicillanic ester.