CAS: 933041-14-6; 6-Bromo-4,5-Dichloropyridazin-3(2H)-One
- 英文名称6-Bromo-4,5-Dichloropyridazin-3(2H)-One
- 中文名称6-溴-4,5-二氯哒嗪-3(2H)-酮
- IUPAC名称6-bromo-4,5-dichloropyridazin-3(2H)-one
- 其它别名6-溴-4,5-二氯-2,3-二氢哒嗪-3-酮; 6-Bromo-4,5-Dichloro-3(2H)-Pyridazinone
- CAS编号933041-14-6
- MFCD编号:MFCD11656268
- EINECS号:891-297-3
- 分子式:C4HBrCl2N2O分子量:243.88
- 产品CID: 1971334
- 产品分类有机原料→分子砌块→芳杂环类化合物→哒嗪类化合物
相似化合物
932-22-9 51355-94-3 1936342-70-9物理性质
MSDS等安全信息
欧盟法规
C&L通报上下游产品
4,5-dichloro-2H-pyridazin-3-one合成工艺路线路线简述
- 932-22-9 = 933041-14-6
反应条件:1.1 Reagents: Bromine Solvents: Water; 30 Min,Rt -> 180 °C
标题:Preparation Of Pyridazinones Derivatives As Herbicidal Compounds
参考文献:World Intellectual Property Organization]
932-22-9 = 933041-14-6
反应条件:1.1 Reagents: Bromine Solvents: Water; 30 Min,Rt -> 180 °C
标题:Preparation Of Substituted Pyrazinecarboxamides As Prmt5-Substrate Adaptor Interaction Inhibitors
参考文献:World Intellectual Property Organization]
932-22-9 = 933041-14-6
反应条件:1.1 Reagents: Bromine Solvents: Water; 30 Min,180 °C; Cooled
标题:Pyridazinone Derivatives As Herbicides And Their Preparation
参考文献:World Intellectual Property Organization]
932-22-9 = 933041-14-6
反应条件:1.1 Reagents: Bromine Solvents: Water; 30 Min,Rt -> 180 °C
标题:Preparation Of Pyridazinediones As Herbicidal Compounds
参考文献:United Kingdom]
932-22-9 = 933041-14-6
反应条件:1.1 Reagents: Bromine Solvents: Water; 30 Min,Rt -> 180 °C
标题:Preparation Of Pyridazinone Derivatives As Herbicides
参考文献:World Intellectual Property Organization]
932-22-9 = 933041-14-6
反应条件:1.1 Reagents: Bromine Solvents: Water; 2 D,90 °C
标题:Studies On Improved Synthesis Of 2'-Deoxyribonucleosides Of Pyridazine Derivatives
作者:Kazimierczuk,Zygmunt; Kaminski,Jaroslaw; Meggio,Flavio
参考文献:Collection Of Czechoslovak Chemical Communications 日期:2006 卷标:71(6) 页码:889-898]
932-22-9 = 933041-14-6
反应条件:1.1 Reagents: Lithium Hydroxide,Bromine Solvents: Methanol; Basified,70 °C
标题:Reductions In Log P Improved Protein Binding And Clearance Predictions Enabling The Prospective Design Of Cannabinoid Receptor (Cb1) Antagonists With Desired Pharmacokinetic Properties
作者:Ellsworth,Bruce A.; Sher,Philip M.; Wu,Ximao; Wu,Gang; Sulsky,Richard B.; Et Al
参考文献:Journal Of Medicinal Chemistry 日期:2013 卷标:56(23) 页码:9586-9600]
= 933041-14-6 [标题:Reaction Conditions
标题:Pyridazinone Herbicidal Compounds
参考文献:United States
📜4,5-二氯-3-羟基哒嗪置于溴体系中,用 水 作为反应溶剂,化学反应 48.0H,以57%的收率获得产物6-溴-4,5-氯-3(2H)-哒嗪
参考文献:Studies On Improved Synthesis Of 2'-Deoxyribonucleosides Of Pyridazine Derivatives
标题:Studies On Improved Synthesis Of 2'-Deoxyribonucleosides Of Pyridazine Derivatives
摘要:通过在丙酮中将相应的卤代哒嗪衍生物的钾盐或dbu盐进行糖基化,制备了一系列卤代哒嗪衍生的2'-脱氧核苷.反应主要产生β-异构体,可通过简单结晶或柱层析纯化.在研究的哒嗪和脱氧核苷中,只有4-溴-6-氯哒嗪-3-酮和6-氯-2-(2'-脱氧核糖呋喃糖基)哒嗪-3-酮显示出对ck2激酶的适度抑制作用.
DOI:10.1135/cccc20060889
